Large-scale testing (Phase 3)Ended earlyNCT04218084What this trial is testingStudy to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Pfizer 236
Large-scale testing (Phase 3)UnknownNCT01511848What this trial is testingStudy Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron OverloadWho this might be right forBeta-thalassemia MajorSickle Cell DiseaseIron Hemosiderosis Ain Shams University 60
Testing effectiveness (Phase 2)Study completedNCT02151526What this trial is testingA Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell DiseaseWho this might be right forBeta-Thalassemia MajorSickle Cell Disease Genetix Biotherapeutics Inc. 7
Not applicableStudy completedNCT00386048What this trial is testingPain Management Protocol for Pediatric Sickle Cell DiseaseWho this might be right forSickle Cell Disease University of South Carolina 50
Not applicableStudy completedNCT02143076What this trial is testingMedication Adherence in Youth With Sickle Cell Disease (SCD)Who this might be right forSickle Cell Disease St. Jude Children's Research Hospital 36
Not applicableUnknownNCT01242878What this trial is testingMACS Study - Microparticles and Coagulation in Sickle Cell DiseaseWho this might be right forSickle Cell Disease University College, London 360
Testing effectiveness (Phase 2)Ended earlyNCT01601340What this trial is testingEffects of HQK-1001 in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell AnemiaSickle Cell Disorders+2 more HemaQuest Pharmaceuticals Inc. 77
Early research (Phase 1)Study completedNCT01848925What this trial is testingStudy of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) PatientsWho this might be right forSickle Cell Disease Prolong Pharmaceuticals 24
Early research (Phase 1)Ended earlyNCT02678143What this trial is testingNonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell DiseaseWho this might be right forSickle Cell Disease Washington University School of Medicine 1
Not applicableStudy completedNCT00456443What this trial is testingInvasive Infections in Children With HemoglobinopathiesWho this might be right forThalassemiaSickle Cell Anemia HaEmek Medical Center, Israel 200
Not applicableUnknownNCT01905787What this trial is testingSickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter StudyWho this might be right forSickle Cell AnemiaSickle Cell β+ or β0 Thalassemia HaEmek Medical Center, Israel 300
Early research (Phase 1)Ended earlyNCT07431398What this trial is testingSingle-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Fulcrum Therapeutics 13
Not applicableStudy completedNCT01602809What this trial is testingMicrovessels and Heart Problems in Sickle Cell DiseaseWho this might be right forSickle Cell Disease National Heart, Lung, and Blood Institute (NHLBI) 65
Testing effectiveness (Phase 2)Study completedNCT02482298What this trial is testingAssess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease AstraZeneca 87
Early research (Phase 1)Study completedNCT05718687What this trial is testingA GBT021601 ADME Microtracer Study in Healthy VolunteersWho this might be right forSickle Cell Disease Pfizer 9
Large-scale testing (Phase 3)Looking for participantsNCT05378555What this trial is testingOral Ketamine for Treatment of Vaso-Occlusive PainWho this might be right forVaso-occlusive Crisis Boston Children's Hospital 10
Not applicableLooking for participantsNCT07392216What this trial is testingFunctional Ovarian Reserve in Sickle Cell DiseaseWho this might be right forSickle Cell Disease St. Jude Children's Research Hospital 440
Testing effectiveness (Phase 2)Ended earlyNCT01000155What this trial is testingEfficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell Anemia Dana-Farber Cancer Institute 5
Very early researchStudy completedNCT04156906What this trial is testingRHD Genotype Matched Red Cells for Anti-DWho this might be right forSickle Cell DiseaseAnti-D Antibodies Children's Hospital of Philadelphia 5
Not applicableLooking for participantsNCT05810181What this trial is testingGene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)Who this might be right forSickle Cell Disease St. Jude Children's Research Hospital 145