Early research (Phase 1)Study completedNCT02712346What this trial is testingThe Role of Endothelin-1 in Sickle Cell DiseaseWho this might be right forSickle Cell Anemia Augusta University 26
Testing effectiveness (Phase 2)Study completedNCT01732718What this trial is testingEffect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell Nephropathy University of North Carolina, Chapel Hill 13
Not applicableLooking for participantsNCT06147414What this trial is testingDevelopment of Non-Invasive Prenatal Diagnosis for Single Gene DisordersWho this might be right forInvasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more Assistance Publique - Hôpitaux de Paris 550
Not applicableEnded earlyNCT00001850What this trial is testingEvaluation of Women With Endocrine and Reproductive-Related ConditionsWho this might be right forEndocrine DiseaseInfertilityLeiomyoma+2 more Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 833
Not applicableEnded earlyNCT01096121What this trial is testingAngiotensin-converting Enzyme Inhibitors and Early Sickle Cell Renal Disease in ChildrenWho this might be right forSickle Cell Disease Assistance Publique - Hôpitaux de Paris 5
Early research (Phase 1)Ended earlyNCT01894594What this trial is testingEfficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell DiseaseWho this might be right forSickle Cell AnemiaChronic Kidney DiseaseMetabolic Acidosis University Hospitals Cleveland Medical Center 7
Not applicableEnded earlyNCT05315908What this trial is testingCOVID-19 Testing in Underserved and Vulnerable PopulationsWho this might be right forHeart FailureCoronary Artery DiseaseCancer+5 more Jesse Nodora 9,120
Not applicableStudy completedNCT01758042What this trial is testingBone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood DisordersWho this might be right forChronic Kidney DiseaseAcute Myeloid Leukemia (AML)Acute Lymphoblastic Leukemia (ALL)+14 more Massachusetts General Hospital 10
Testing effectiveness (Phase 2)WithdrawnNCT06286046What this trial is testingMitapivat in Participants With Sickle Cell Disease and NephropathyWho this might be right forSickle Cell DiseaseNephropathy Agios Pharmaceuticals, Inc.
Not applicableLooking for participantsNCT07561957What this trial is testingA Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) GuidelinesWho this might be right forChronic Kidney DiseaseProteinuriaBlood Pressure Control+5 more St. James's Hospital, Ireland 80
Not applicableLooking for participantsNCT07064174What this trial is testingSickle Cell Kidney BiorepositoryWho this might be right forSickle Cell TraitSickle Cell Disease (SCD)Chronic Kidney Disease University of Texas Southwestern Medical Center 800
Not applicableStudy completedNCT07554547What this trial is testingCrizanlizumab Pregnancy Outcomes Intensive MonitoringWho this might be right forSickle Cell Disease Novartis Pharmaceuticals 13
Testing effectiveness (Phase 2)Study completedNCT03806452What this trial is testingSIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)Who this might be right forSickle Cell Disease Theravia 86
Not applicableStudy completedNCT03938324What this trial is testingPeer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic ConditionsWho this might be right forSickle Cell DiseaseChronic Kidney DiseasesSystemic Lupus Erythematosus+6 more Duke University 222
Not applicableLooking for participantsNCT07488091What this trial is testingMulti Disciplinary Sickle Cell Disease Obstetrics Care Program in GhanaWho this might be right forSickle Cell Disease and Pregnancy University of Ghana Medical School 198
Testing effectiveness (Phase 2)Looking for participantsNCT07175051What this trial is testingTargeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, EmpagliflozinWho this might be right forSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Albuminuria University of Illinois at Chicago 20
Not applicableLooking for participantsNCT05153967What this trial is testingCooperative Assessment of Late Effects for SCD Curative TherapiesWho this might be right forSickle Cell DiseasePulmonary DiseaseRenal Disease+1 more Vanderbilt University Medical Center 750
Not applicableStudy completedNCT04057521What this trial is testingCoordinated HEalthcare for Complex KidsWho this might be right forAsthmaDiabetes MellitusSickle Cell Disease+1 more University of Illinois at Chicago 6,259
Testing effectiveness (Phase 2)Ended earlyNCT02373241What this trial is testingPreventing Sickle Cell Kidney DiseaseWho this might be right forAnemia, Sickle CellSickle Cell DiseaseKidney Disease+2 more University of Alabama at Birmingham 1
Not applicableStudy completedNCT04574050What this trial is testingSELF-BREATHE RCT for Chronic BreathlessnessWho this might be right forCancerCOPDAsthma+9 more King's College Hospital NHS Trust 52