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Results for “Sickle Cell-beta-thalassemia”

84 trials

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Showing 20 of 84 results

Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableStudy completedNCT02326597
What this trial is testing

Decision Aid for Therapeutic Options In Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseSickle Cell AnemiaHemoglobin SS+2 more
Emory University 134
Testing effectiveness (Phase 2)Study completedNCT01186419
What this trial is testing

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-thalassemia
Shire 51
Testing effectiveness (Phase 2)Active Not RecruitingNCT05353647
What this trial is testing

A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)

Who this might be right for
Sickle Cell Disease
David Williams 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT05357482
What this trial is testing

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Who this might be right for
Sickle Cell AnemiaBeta Thalassemia
National Heart, Lung, and Blood Institute (NHLBI) 40
Testing effectiveness (Phase 2)Looking for participantsNCT03653338
What this trial is testing

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Who this might be right for
Sickle Cell AnemiaBeta-thalassemia MajorDiamond-blackfan Anemia
Paul Szabolcs 5
Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Testing effectiveness (Phase 2)Looking for participantsNCT04008368
What this trial is testing

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Who this might be right for
Myeloid Chimerism
National Heart, Lung, and Blood Institute (NHLBI) 32
Not applicableStudy completedNCT02258997
What this trial is testing

Hepcidin Levels in Sickle Cell Disease (SCD)

Who this might be right for
Sickle Cell AnemiaSickle - Beta Thalassemia
Kenneth Ataga, MD 42
Testing effectiveness (Phase 2)Ended earlyNCT01363908
What this trial is testing

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Who this might be right for
Transfusional Iron OverloadBeta-Thalassemia
Shire 30
Early research (Phase 1)Study completedNCT00005783
What this trial is testing

A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders

Who this might be right for
Hemoglobin SC DiseaseSickle Cell Anemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50
Large-scale testing (Phase 3)UnknownNCT04191213
What this trial is testing

Gum Arabic as Anti-oxidant, Anti-inflammatory and Fetal Hemoglobin Inducing Agent in Sickle Cell Anemia Patients

Who this might be right for
Sickle Cell Anemia in Children
Al-Neelain University 100
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Large-scale testing (Phase 3)UnknownNCT01511848
What this trial is testing

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Who this might be right for
Beta-thalassemia MajorSickle Cell DiseaseIron Hemosiderosis
Ain Shams University 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
Not applicableActive Not RecruitingNCT05675436
What this trial is testing

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

Who this might be right for
Sickle Cell AnemiaSickle Cell ThalassemiaSickle Cell Pain+5 more
National Heart, Lung, and Blood Institute (NHLBI) 6
Not applicableEnrolling By InvitationNCT06363760
What this trial is testing

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Who this might be right for
Sickle Cell DiseaseTransfusion-dependent Beta-ThalassemiaHemoglobinopathies
Editas Medicine, Inc. 54
Not applicableActive Not RecruitingNCT04691323
What this trial is testing

The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.

Who this might be right for
Sickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 68
Not applicableStudy completedNCT00005893
What this trial is testing

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Who this might be right for
NeutropeniaSickle Cell AnemiaThalassemia Major+1 more
Fairview University Medical Center
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