Early research (Phase 1)Study completedNCT02712346What this trial is testingThe Role of Endothelin-1 in Sickle Cell DiseaseWho this might be right forSickle Cell Anemia Augusta University 26
Testing effectiveness (Phase 2)WithdrawnNCT01419704What this trial is testingPhase I/II Pilot Study of Mixed Chimerism to Treat HemoglobinopathiesWho this might be right forAnemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more Talaris Therapeutics Inc.
Not applicableUnknownNCT04090268What this trial is testingPrecision Exercise in Children With Malignant HemopathiesWho this might be right forLeukemia, Myeloid, AcuteLeukemia, B-cellLeukemia, T Cell+5 more University of Milano Bicocca 380
Not applicableStudy completedNCT04691323What this trial is testingThe Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.Who this might be right forSickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more Ann & Robert H Lurie Children's Hospital of Chicago 68
Not applicableStudy completedNCT02197845What this trial is testingEnhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient NavigatorsWho this might be right forSickle Cell Disease Virginia Commonwealth University 353
Not applicableLooking for participantsNCT03937817What this trial is testingCollection of Human Biospecimens for Basic and Clinical Research Into Globin VariantsWho this might be right forAlpha and Beta ThalassemiaSickle Cell DiseaseMalaria+1 more National Institute of Allergy and Infectious Diseases (NIAID) 300
Not applicableStudy completedNCT04688411What this trial is testingAn mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Beta Zero ThalassemiaSickle B+ Thalassemia+1 more Ann & Robert H Lurie Children's Hospital of Chicago 36
Early research (Phase 1)Looking for participantsNCT01245179What this trial is testingStudy of Panobinostat (LBH589) in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Abdullah Kutlar 18
Early research (Phase 1)Study completedNCT00005783What this trial is testingA Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling DisordersWho this might be right forHemoglobin SC DiseaseSickle Cell Anemia National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50
Testing effectiveness (Phase 2)Study completedNCT02435901What this trial is testingHSCT For Patients With High Risk Hemoglobinopathies Using Reduced IntensityWho this might be right forSickle Cell DiseaseBeta Thalassemia-Major Northwell Health 29
Not applicableStudy completedNCT02258997What this trial is testingHepcidin Levels in Sickle Cell Disease (SCD)Who this might be right forSickle Cell AnemiaSickle - Beta Thalassemia Kenneth Ataga, MD 42
Not applicableStudy completedNCT01715480What this trial is testingEffect of Broccoli Sprouts Homogenate on SS RBCWho this might be right forSickle Red Blood CellFetal HemoglobinOxidative Stress Duke University 21
Early research (Phase 1)Active Not RecruitingNCT03282656What this trial is testingGene Transfer for Sickle Cell DiseaseWho this might be right forSickle Cell Disease David Williams 10
Not applicableLooking for participantsNCT04416178What this trial is testingSickle Cell Disease and the Genomic and Gene Therapy Needs of StakeholdersWho this might be right forSickle Cell Disease St. Jude Children's Research Hospital 352
Not applicableNot Yet RecruitingNCT05883254What this trial is testingPumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia IntermediaWho this might be right forSickle Cell Disease, Beta Thalassemia Intermedia Assiut University 80
Large-scale testing (Phase 3)Looking for participantsNCT05477563What this trial is testingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseWho this might be right forBeta-ThalassemiaThalassemiaHematologic Diseases+4 more Vertex Pharmaceuticals Incorporated 26
Early research (Phase 1)Study completedNCT01522547What this trial is testingStudy to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell DiseaseWho this might be right forAnemia, Sickle Cell Celgene 12
Not applicableTemporarily Not AvailableNCT07640815What this trial is testingExpanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell DiseaseWho this might be right forSickle Cell Disease David Williams
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623What this trial is testingThe BENeFiTS Trial in Beta Thalassemia IntermediaWho this might be right forBeta Thalassemia IntermediaSickle Cell Disease Phoenicia BioScience 36
Testing effectiveness (Phase 2)Study completedNCT00029380What this trial is testingCord Blood Transplantation for Sickle Cell Anemia and ThalassemiaWho this might be right forHematologic DiseasesAnemia, Sickle CellBeta-Thalassemia+1 more National Heart, Lung, and Blood Institute (NHLBI) 30