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Results for “Sickle Cell-thalassemia Disease”

176 trials

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Showing 20 of 176 results

Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Testing effectiveness (Phase 2)Ended earlyNCT02504619
What this trial is testing

Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseThalassemia
Gamida Cell ltd 1
Not applicableStudy completedNCT00456443
What this trial is testing

Invasive Infections in Children With Hemoglobinopathies

Who this might be right for
ThalassemiaSickle Cell Anemia
HaEmek Medical Center, Israel 200
Large-scale testing (Phase 3)Study completedNCT00235391
What this trial is testing

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Who this might be right for
ThalassemiaSickle Cell DiseaseDiamond Blackfan Anemia+1 more
Novartis Pharmaceuticals 1,683
Not applicableUnknownNCT00596999
What this trial is testing

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

Who this might be right for
Hematologic Malignancies
Celgene Corporation 6
Early research (Phase 1)Study completedNCT06813924
What this trial is testing

A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants

Who this might be right for
Healthy Volunteers Sickle Cell Disease, Thalassemia
Novo Nordisk A/S 37
Not applicableLooking for participantsNCT05414045
What this trial is testing

Autologous Testicular Tissue Transplantation

Who this might be right for
CancerSickle Cell ThalassemiaHematologic Diseases
Universitair Ziekenhuis Brussel 5
Not applicableUnknownNCT01905787
What this trial is testing

Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study

Who this might be right for
Sickle Cell AnemiaSickle Cell β+ or β0 Thalassemia
HaEmek Medical Center, Israel 300
Testing effectiveness (Phase 2)Looking for participantsNCT05736419
What this trial is testing

Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Who this might be right for
Sickle Cell DiseaseThalassemia, BetaThalassemia
Memorial Sloan Kettering Cancer Center 24
Testing effectiveness (Phase 2)UnknownNCT00061568
What this trial is testing

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

Who this might be right for
Congenital Hemolytic AnemiaSickle Cell Disease
National Heart, Lung, and Blood Institute (NHLBI) 130
Post-approval studies (Phase 4)Study completedNCT00749515
What this trial is testing

Pilot Study for Patients With Poor Response to Deferasirox

Who this might be right for
Transfusion-dependent HemachromatosisThalassemia MajorSickle Cell Disease
Boston Children's Hospital 15
Large-scale testing (Phase 3)UnknownNCT01511848
What this trial is testing

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Who this might be right for
Beta-thalassemia MajorSickle Cell DiseaseIron Hemosiderosis
Ain Shams University 60
Testing effectiveness (Phase 2)Ended earlyNCT06078696
What this trial is testing

Siplizumab for Sickle Cell Disease Transplant

Who this might be right for
Anemia, Sickle Cell
Columbia University 1
Large-scale testing (Phase 3)Study completedNCT00171821
What this trial is testing

A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload

Who this might be right for
Transfusion-dependent Iron Overload
Novartis Pharmaceuticals 1,784
Not applicableStudy completedNCT00736060
What this trial is testing

Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever

Who this might be right for
Sickle Cell AnemiaSickle Cell Thalassemia
HaEmek Medical Center, Israel 60
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623
What this trial is testing

The BENeFiTS Trial in Beta Thalassemia Intermedia

Who this might be right for
Beta Thalassemia IntermediaSickle Cell Disease
Phoenicia BioScience 36
Not applicableStudy completedNCT00971698
What this trial is testing

The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia

Who this might be right for
Sickle Cell AnemiaThalassemia
HaEmek Medical Center, Israel 50
Not applicableStudy completedNCT07180836
What this trial is testing

Prevalence and Hematological Characteristics of Hemoglobinopathies

Who this might be right for
Hemoglobinopathies
Bacha Khan Medical College 839
Early research (Phase 1)Study completedNCT02165007
What this trial is testing

Haploidentical Hematopoietic Stem Cell Transplantation

Who this might be right for
Sickle Cell-thalassemia DiseaseThalassemia
Catherine Bollard 7
Testing effectiveness (Phase 2)Ended earlyNCT02065869
What this trial is testing

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Who this might be right for
Acute Lymphoblastic LeukemiaLeukemia, Acute Myeloid (AML), ChildLymphoma, Non-Hodgkin+10 more
Bellicum Pharmaceuticals 187
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