Testing effectiveness (Phase 2)WithdrawnNCT04474626What this trial is testingIsoquercetin in Sickle Cell AnemiaWho this might be right forSickle Cell DiseaseSickle Cell-Beta0-Thalassemia Jeffrey Zwicker, MD
Not applicableUnknownNCT04090268What this trial is testingPrecision Exercise in Children With Malignant HemopathiesWho this might be right forLeukemia, Myeloid, AcuteLeukemia, B-cellLeukemia, T Cell+5 more University of Milano Bicocca 380
Testing effectiveness (Phase 2)Active Not RecruitingNCT00061568What this trial is testingImproving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasWho this might be right forCongenital Hemolytic AnemiaSickle Cell Disease National Heart, Lung, and Blood Institute (NHLBI) 130
Not applicableStudy completedNCT01241357What this trial is testingHigh-Tc Susceptometer to Monitor Transfusional Iron OverloadWho this might be right forTransfusional Iron OverloadThalassemia MajorSickle Cell Disease+2 more Columbia University 99
Large-scale testing (Phase 3)Study completedNCT01179217What this trial is testingA Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemiaWho this might be right forSickle Cell AnemiaSickle ß0-Thalassemia Emmaus Medical, Inc. 230
Testing effectiveness (Phase 2)Study completedNCT04987489What this trial is testingEtavopivat in Patients With Thalassemia or Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseThalassemia Forma Therapeutics, Inc. 53
Early research (Phase 1)Study completedNCT00005783What this trial is testingA Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling DisordersWho this might be right forHemoglobin SC DiseaseSickle Cell Anemia National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 50
Not applicableStudy completedNCT03715972What this trial is testingCerebrovascular Reserve and White Matter Disease in Patients with Chronic AnemiaWho this might be right forThalassemiaSickle Cell DiseaseHealthy Controls Children's Hospital Los Angeles 165
Testing effectiveness (Phase 2)Study completedNCT02435901What this trial is testingHSCT For Patients With High Risk Hemoglobinopathies Using Reduced IntensityWho this might be right forSickle Cell DiseaseBeta Thalassemia-Major Northwell Health 29
Post-approval studies (Phase 4)Enrolling By InvitationNCT05777993What this trial is testingProvide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat StudyWho this might be right forPyruvate Kinase DeficiencyAnemia, HemolyticSickle Cell Disease+1 more Agios Pharmaceuticals, Inc. 59
Testing effectiveness (Phase 2)WithdrawnNCT01419704What this trial is testingPhase I/II Pilot Study of Mixed Chimerism to Treat HemoglobinopathiesWho this might be right forAnemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more Talaris Therapeutics Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT04053803What this trial is testingAn Extension Study of IMR-687 in Adult Patients With Sickle Cell AnemiaWho this might be right forSickle Cell Disease Imara, Inc. 30
Not applicableLooking for participantsNCT06250595What this trial is testingEuropean Rare Blood Disorders Platform (ENROL)Who this might be right forAnemiaBone Marrow FailureBleeding Disorder+9 more Hospital Universitari Vall d'Hebron Research Institute 37,090
Testing effectiveness (Phase 2)Study completedNCT03763656What this trial is testingPharmacokinetics of Oral Hydroxyurea SolutionWho this might be right forSickle Cell DiseaseSickle-Cell; Hemoglobin Disease, ThalassemiaSickle Cell-beta-thalassemia+1 more Nova Laboratories Limited 33
Testing effectiveness (Phase 2)Study completedNCT00125788What this trial is testingL-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 ThalassemiaWho this might be right forSickle Cell AnemiaThalassemia Emmaus Medical, Inc. 70
Not applicableStudy completedNCT07305181What this trial is testingPrevalence of Abnormal Haemoglobin Variants in Metropolitan Chattogram, BangladeshWho this might be right forHbE TraitHemoglobinopathies Bangladesh Bioscience Research Group 8,400
Post-approval studies (Phase 4)Study completedNCT03176849What this trial is testingPhase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCTWho this might be right forVitamin D DeficiencyStem Cell Transplant ComplicationsPediatric Cancer+7 more Phoenix Children's Hospital 49
Not applicableEnded earlyNCT01534676What this trial is testingEffects of Transfusion of Older Stored Red CellsWho this might be right forSickle Cell DiseaseThalassemia Columbia University 3
Testing effectiveness (Phase 2)UnknownNCT02061800What this trial is testingCD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell TransplantWho this might be right forChronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more Diane George 14
Not applicableLooking for participantsNCT04528355What this trial is testingData Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RICWho this might be right forPrimary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more Paul Szabolcs 50