Not applicableStudy completedNCT01158794What this trial is testingGenes Influencing Iron Overload StateWho this might be right forSickle Cell DiseaseThalassemiaMarrow Aplasia St. Jude Children's Research Hospital 50
Testing effectiveness (Phase 2)Ended earlyNCT00586209What this trial is testingL-Glutamine Therapy for Sickle Cell AnemiaWho this might be right forSickle Cell AnemiaThalassemia Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 15
Testing effectiveness (Phase 2)Ended earlyNCT02504619What this trial is testingAllogeneic SCT of CordIn™, in Patients With HemoglobinopathiesWho this might be right forSickle Cell DiseaseThalassemia Gamida Cell ltd 1
Not applicableStudy completedNCT03609814What this trial is testingStudy of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)Who this might be right forHematologic MalignanciesNonmalignant DiseasesImmunodeficiencies+5 more University of California, San Francisco 30
Testing effectiveness (Phase 2)Study completedNCT03763656What this trial is testingPharmacokinetics of Oral Hydroxyurea SolutionWho this might be right forSickle Cell DiseaseSickle-Cell; Hemoglobin Disease, ThalassemiaSickle Cell-beta-thalassemia+1 more Nova Laboratories Limited 33
Early research (Phase 1)Active Not RecruitingNCT03282656What this trial is testingGene Transfer for Sickle Cell DiseaseWho this might be right forSickle Cell Disease David Williams 10
Early research (Phase 1)Study completedNCT06433661What this trial is testingA Research Study of the Effect of Food on Etavopivat in Healthy ParticipantsWho this might be right forHealthy Volunteers Sickle Cell Disease, Thalassemia Novo Nordisk A/S 16
Testing effectiveness (Phase 2)Study completedNCT04987489What this trial is testingEtavopivat in Patients With Thalassemia or Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseThalassemia Forma Therapeutics, Inc. 53
Testing effectiveness (Phase 2)Looking for participantsNCT05736419What this trial is testingImmune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)Who this might be right forSickle Cell DiseaseThalassemia, BetaThalassemia Memorial Sloan Kettering Cancer Center 24
Early research (Phase 1)Study completedNCT01039636What this trial is testingSafety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron OverloadWho this might be right forTransfusional Iron OverloadBeta-thalassemia FerroKin BioSciences, Inc. 20
Testing effectiveness (Phase 2)Looking for participantsNCT04008368What this trial is testingRepeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism LevelsWho this might be right forMyeloid Chimerism National Heart, Lung, and Blood Institute (NHLBI) 32
Testing effectiveness (Phase 2)Active Not RecruitingNCT00061568What this trial is testingImproving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasWho this might be right forCongenital Hemolytic AnemiaSickle Cell Disease National Heart, Lung, and Blood Institute (NHLBI) 130
Not applicableEnrolling By InvitationNCT06363760What this trial is testingA Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301Who this might be right forSickle Cell DiseaseTransfusion-dependent Beta-ThalassemiaHemoglobinopathies Editas Medicine, Inc. 54
Not applicableLooking for participantsNCT01758042What this trial is testingBone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood DisordersWho this might be right forChronic Kidney DiseaseAcute Myeloid Leukemia (AML)Acute Lymphoblastic Leukemia (ALL)+14 more Massachusetts General Hospital 10
Not applicableActive Not RecruitingNCT03376893What this trial is testingEpidemiology of Silent and Overt Strokes in Sickle Cell DiseaseWho this might be right forAnemia, Sickle CellSickle Cell DiseaseStroke+2 more Vanderbilt University Medical Center 102
Testing effectiveness (Phase 2)Ended earlyNCT01000155What this trial is testingEfficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell Anemia Dana-Farber Cancer Institute 5
Not applicableActive Not RecruitingNCT04523376What this trial is testingPilot Study PBSCT with TCRab Depletion for HemoglobinopathiesWho this might be right forSickle Cell DiseaseThalassemia Major Timothy Olson 9
Not applicableEnrolling By InvitationNCT06664541What this trial is testingDecision-Making and Quality of Life Surrounding Hematologic Disease and Gene TherapyWho this might be right forTransfusion Dependent Beta ThalassemiaSickle Cell Disease Georgetown University 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT02105766What this trial is testingNonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant FailureWho this might be right forSickle Cell DiseaseThalassemiaStem Cell Transplantation+1 more National Heart, Lung, and Blood Institute (NHLBI) 56
Large-scale testing (Phase 3)Looking for participantsNCT05477563What this trial is testingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseWho this might be right forBeta-ThalassemiaThalassemiaHematologic Diseases+4 more Vertex Pharmaceuticals Incorporated 26