Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Single-gene Disorders”

407 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 407 results

Not applicableStudy completedNCT07613879
What this trial is testing

Mulligan Mobilization and Stabilization Exercises for Sensorimotor Function in Women With Text Neck Syndrome

Who this might be right for
Neck PainText Neck SyndromeCumulative Trauma Disorders+1 more
Pamukkale University 38
Early research (Phase 1)Looking for participantsNCT07246941
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington's Disease

Who this might be right for
Huntington's Disease
Hoffmann-La Roche 40
Testing effectiveness (Phase 2)Study completedNCT01671072
What this trial is testing

Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis

Who this might be right for
Degenerative Arthritis
Kolon Life Science 54
Early research (Phase 1)Study completedNCT05398029
What this trial is testing

VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaAtherosclerotic Cardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT03374657
What this trial is testing

A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa

Who this might be right for
Retinitis Pigmentosa
Novartis Pharmaceuticals 12
Not applicableUnknownNCT00549029
What this trial is testing

The Association of Genetic Polymorphisms With Statin-Induced Myopathy.

Who this might be right for
RhabdomyolysisMyopathy
National Taiwan University Hospital 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT06100276
What this trial is testing

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

Who this might be right for
Amyotrophic Lateral Sclerosis
UniQure Biopharma B.V. 20
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Testing effectiveness (Phase 2)Looking for participantsNCT07226206
What this trial is testing

A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

Who this might be right for
Hemophilia A
Hoffmann-La Roche 5
Not applicableLooking for participantsNCT05033691
What this trial is testing

Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases

Who this might be right for
NSCLCEGFR Gene MutationEGF-R Positive Non-Small Cell Lung Cancer+2 more
Hadassah Medical Organization 162
Testing effectiveness (Phase 2)Ended earlyNCT03652259
What this trial is testing

Gene Delivery Clinical Trial of SRP-9003 (Bidridistrogene Xeboparvovec) for Participants With Limb-Girdle Muscular Dystrophy, Type 2E (LGMD2E) (Beta-Sarcoglycan Deficiency)

Who this might be right for
Limb-Girdle Muscular Dystrophy, Type 2E
Sarepta Therapeutics, Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT06980948
What this trial is testing

Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

Who this might be right for
Chronic Neuropathic Pain
Sangamo Therapeutics 27
Large-scale testing (Phase 3)Study completedNCT04323098
What this trial is testing

Study to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec, With Prophylactic Steroids in Hemophilia A

Who this might be right for
Hemophilia A
BioMarin Pharmaceutical 22
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07150416
What this trial is testing

Nebulized Inhalation of Recombinant Human p53 Adenovirus Injection for Treatment of Multiple Ground-Glass Lung Nodules: A Single-Arm Clinical Study

Who this might be right for
Multiple Pulmonary Ground-Glass NodulesLung NeoplasmsPrecancerous Conditions
The First Affiliated Hospital of Guangzhou Medical University 38
Very early researchUnknownNCT05180851
What this trial is testing

Safety and Efficacy of Recombinant Oncolytic Adenovirus L-IFN Injection in Relapsed/Refractory Solid Tumors Clinical Study

Who this might be right for
Head and Neck CancerMelanomaBreast Cancer+4 more
Shanghai Fengxian District Central Hospital 28
Testing effectiveness (Phase 2)UnknownNCT04592666
What this trial is testing

Almonertinib/Pemetrexed/Carboplatin in EGFR T790M+ Advanced Lung Cancer

Who this might be right for
Lung Cancer, Non-small CellEGFR T790MEGFR Gene Mutation
Fudan University 226
Testing effectiveness (Phase 2)Looking for participantsNCT06378892
What this trial is testing

Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib

Who this might be right for
Non Small Cell Lung Cancer MetastaticALK Gene Mutation
Centro di Riferimento Oncologico - Aviano 45
Early research (Phase 1)UnknownNCT02727764
What this trial is testing

A Single Dose Clinical Trial to Study the Safety of ART-I02 in Patients With Arthritis

Who this might be right for
Arthritis, RheumatoidOsteo Arthritis
Arthrogen 12
Testing effectiveness (Phase 2)Looking for participantsNCT06421831
What this trial is testing

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Who this might be right for
Spinal Muscular Atrophy Type 3
GeneCradle Inc 21
Testing effectiveness (Phase 2)Looking for participantsNCT05747261
What this trial is testing

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL)

Who this might be right for
Spinal Muscular Atrophy (SMA)
Biocad 40
Load More Results