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Results for “Sinonasal Tract Tumor”

24 trials

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Showing 20 of 24 results

Testing effectiveness (Phase 2)WithdrawnNCT05879484
What this trial is testing

Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS

Who this might be right for
Sinonasal CancerSquamous Non-small Cell Lung CancerLung Cancer+3 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT06636734
What this trial is testing

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more
Emory University
Not applicableNot Yet RecruitingNCT07512466
What this trial is testing

Evaluation of Endoscopic Management of Sinonasal Tumors In Difficult Anatomical Locations

Who this might be right for
Nasal Cavity and Paranasal Sinus Cancer
Assiut University 25
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT06940180
What this trial is testing

Toripalimab With Chemotherapy for Sinus Cancer

Who this might be right for
Sinonasal CancerParanasal Sinus NeoplasmsSquamous Cell Carcinoma+2 more
Dana-Farber Cancer Institute 20
Not applicableNo Longer AvailableNCT03874455
What this trial is testing

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Who this might be right for
Epithelioid Sarcoma (Ex-US Only)Spindle Cell SarcomaSinonasal Carcinoma+17 more
Epizyme, Inc.
Testing effectiveness (Phase 2)Study completedNCT03274414
What this trial is testing

A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages

Who this might be right for
Paranasal Sinus CancerNasal Cavity TumorNasal Cavity Adenocarcinoma
Memorial Sloan Kettering Cancer Center 3
Early research (Phase 1)Active Not RecruitingNCT04576091
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma+29 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT05172245
What this trial is testing

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown Primary+24 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT05114707
What this trial is testing

Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses

Who this might be right for
Nasal Cavity CancerParanasal Sinus CancerCamrelizumab+3 more
Sun Yat-sen University 57
Not applicableStudy completedNCT04788264
What this trial is testing

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Who this might be right for
Head and Neck CarcinomaHypopharyngeal CarcinomaLaryngeal Carcinoma+13 more
Thomas Jefferson University 12
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552
What this trial is testing

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
National Cancer Institute (NCI)
Not applicableLooking for participantsNCT05607888
What this trial is testing

Prospective Study of Sinonasal and Skull-base Tumours Management

Who this might be right for
Nasal NeoplasmNasal Neoplasm BenignSkull Base Neoplasms+3 more
University Medical Centre Ljubljana 120
Testing effectiveness (Phase 2)Looking for participantsNCT07209189
What this trial is testing

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Who this might be right for
Head and Neck CancerSquamous Cell CarcinomaOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 75
Not applicableLooking for participantsNCT06662058
What this trial is testing

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Cutaneous Squamous Cell Carcinoma of the Head and NeckHead and Neck Carcinoma of Unknown Primary+30 more
Emory University 118
Not applicableUnknownNCT03942380
What this trial is testing

Cell-free Tumor DNA in Head and Neck Cancer Patients

Who this might be right for
Head and Neck CancerHead and Neck NeoplasmsHead and Neck Squamous Cell Carcinoma+24 more
Christian von Buchwald 500
Early research (Phase 1)Looking for participantsNCT07156227
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Hypopharyngeal Squamous Cell Carcinoma+27 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT01827423
What this trial is testing

Squamous Cell Carcinoma Antigen Analysis at the University Hospital Ostrava

Who this might be right for
Nasal PolypsNasal DiseasesPapilloma
University Hospital Ostrava 20
Testing effectiveness (Phase 2)Looking for participantsNCT06814496
What this trial is testing

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Who this might be right for
MelanomaMedullary Thyroid CancerSinonasal Undifferentiated Carcinoma+8 more
University of Arizona 30
Large-scale testing (Phase 3)Study completedNCT00117572
What this trial is testing

Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE)

Who this might be right for
Cancer of the PharynxCancer of the LarynxCancer of the Nasal Cavity+2 more
University of Chicago 285
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