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Results for “Sitravatinib”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04734262
What this trial is testing

A Phase II Study to Explore the Safety, Tolerability, and Preliminary Antitumor Activity of Sitravatinib Plus Tislelizumab or Combination With Nab-paclitaxel in Patients With Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Metastatic Breast Cancer
Fudan University 98
Early research (Phase 1)Study completedNCT05255276
What this trial is testing

PK Study to Assess Drug-drug Interaction Between Sitravatinib and a P-gp Inducer and an Inhibitor.

Who this might be right for
Healthy Adults
Mirati Therapeutics Inc. 36
Early research (Phase 1)Study completedNCT04887194
What this trial is testing

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Who this might be right for
Advanced Solid Tumor
Mirati Therapeutics Inc. 40
Very early researchStudy completedNCT03575598
What this trial is testing

Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study

Who this might be right for
Squamous Cell Carcinoma, Head And NeckSquamous Cell Carcinoma MouthSquamous Cell Carcinoma of the Oral Cavity
University Health Network, Toronto 10
Testing effectiveness (Phase 2)Study completedNCT05542342
What this trial is testing

Sitravatinib and Tislelizumab in Patients With Metastatic Uveal Melanoma With Liver Metastases.

Who this might be right for
Uveal Melanoma With Liver Metastases
Grupo Español Multidisciplinar de Melanoma 16
Testing effectiveness (Phase 2)WithdrawnNCT05614453
What this trial is testing

Tislelizumab in Combination With Sitravatinib for Recurrent/Metastatic Cervical Cancer After Platinum-Based Chemotherapy

Who this might be right for
Metastatic Cervical Cancer
Australia New Zealand Gynaecological Oncology Group
Testing effectiveness (Phase 2)Ended earlyNCT05176925
What this trial is testing

Tislelizumab Combined With Sitravatinib as Consolidation Treatment Following Concurrent Chemoradiation in Patients With Locally Advanced, Unresectable NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Fudan University 5
Testing effectiveness (Phase 2)Ended earlyNCT03606174
What this trial is testing

Sitravatinib in Combination With PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaUrothelial Carcinoma BladderUrothelial Carcinoma Ureter+2 more
Mirati Therapeutics Inc. 260
Testing effectiveness (Phase 2)Ended earlyNCT05461794
What this trial is testing

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 96
Testing effectiveness (Phase 2)WithdrawnNCT05419817
What this trial is testing

Pembrolizumab With Sitravatinib in Recurrent Endometrial Cancer and Other Solid Tumors With Deficient Mismatch Repair System

Who this might be right for
Recurrent Endometrial CancerSolid Tumors
Haider Mahdi
Large-scale testing (Phase 3)Study completedNCT03906071
What this trial is testing

Phase 3 Study of Sitravatinib Plus Nivolumab vs Docetaxel in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Non-Squamous Non-Small Cell Lung Cancer
Mirati Therapeutics Inc. 577
Early research (Phase 1)Study completedNCT04472650
What this trial is testing

Relative Bioavailability of Two Different Capsule Formulations of Sitravatinib in Healthy Adults

Who this might be right for
Tumor
BeiGene 26
Early research (Phase 1)Study completedNCT04518046
What this trial is testing

Study of Sitravatinib, Nivolumab and Ipilimumab in Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies

Who this might be right for
Clear-Cell Renal Cell Carcinoma
Mirati Therapeutics Inc. 22
Testing effectiveness (Phase 2)UnknownNCT05407519
What this trial is testing

Evaluate Tislelizumab Combined With Sitravatinib as Adjuvant Therapy in Participants With HCC at High Risk of Recurrence After Curative Resection

Who this might be right for
Hepatocellular Carcinoma
Anhui Provincial Hospital 40
Early research (Phase 1)Study completedNCT04772612
What this trial is testing

Evaluate the Effect of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Sitravatinib

Who this might be right for
Hepatic Impairment
Mirati Therapeutics Inc. 30
Testing effectiveness (Phase 2)Ended earlyNCT04904302
What this trial is testing

Sitravatinib and Nivolumab for the Treatment of Metastatic or Advanced Clear Cell Renal Cell Cancer

Who this might be right for
Advanced Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v8
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)UnknownNCT05228496
What this trial is testing

Investigate the Efficacy and Safety of Tislelizumab Combined With Sitravatinib as Maintenance Therapy for ES-SCLC

Who this might be right for
Lung Cancer, Small Cell
Zhejiang Cancer Hospital 21
Testing effectiveness (Phase 2)Study completedNCT03015740
What this trial is testing

Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney Cancer

Who this might be right for
Clear Cell Renal Cell CarcinomaMetastatic Kidney CarcinomaStage III Renal Cell Cancer AJCC v7+1 more
M.D. Anderson Cancer Center 42
Testing effectiveness (Phase 2)Ended earlyNCT04123704
What this trial is testing

Sitravatinib in Metastatic Breast Cancer

Who this might be right for
Breast Cancer Stage IVTriple Negative Breast CancerBreast Neoplasms+1 more
Xiang Zhang 3
Early research (Phase 1)Study completedNCT03666143
What this trial is testing

A Phase 1b Study to Assess Sitravatinib in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
BeiGene 216
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