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Results for “Solid Tumor Leptomeningeal Metastasis”

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Showing 19 of 0 results

Testing effectiveness (Phase 2)WithdrawnNCT04315246
What this trial is testing

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

Who this might be right for
Leptomeningeal MetastasisSolid Tumor, Adult
Y-mAbs Therapeutics
Testing effectiveness (Phase 2)Study completedNCT05865990
What this trial is testing

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease

Who this might be right for
Metastatic Breast CancerAdvanced Non-Small Cell Squamous Lung CancerSolid Tumor, Adult
MedSIR 63
Not applicableEnded earlyNCT00964743
What this trial is testing

Depocyt® With Sorafenib in Neoplastic Meningitis

Who this might be right for
Neoplastic Meningitis
H. Lee Moffitt Cancer Center and Research Institute 2
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Early research (Phase 1)Study completedNCT03520504
What this trial is testing

Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 24
Early research (Phase 1)WithdrawnNCT07199413
What this trial is testing

Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Medical College of Wisconsin
Early research (Phase 1)Active Not RecruitingNCT04192981
What this trial is testing

GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Memorial Sloan Kettering Cancer Center 21
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Ended earlyNCT00005812
What this trial is testing

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

Who this might be right for
Brain TumorsCentral Nervous System TumorsLeptomeningeal Metastases
Dartmouth-Hitchcock Medical Center 12
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Not applicableStudy completedNCT06592092
What this trial is testing

Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3+ Solid Tumors

Who this might be right for
Solid TumorMeningeal Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07751744
What this trial is testing

Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma

Who this might be right for
Brain Metastases From Solid TumorsLeptomeningeal DiseaseHigh Grade Glioma (HGG)+1 more
Jubilant Therapeutics Inc. 113
Testing effectiveness (Phase 2)Active Not RecruitingNCT06809530
What this trial is testing

Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisPemetrexedPD-1 Inhibitor+2 more
Guangzhou Medical University 34
Early research (Phase 1)Looking for participantsNCT05477927
What this trial is testing

Dual-targeting VEGFR1 and PD-L1 CAR-T for Pleural, Peritoneal, or Leptomeningeal Metastases

Who this might be right for
Malignant Peritoneal EffusionMalignant AscitesSerous Cavity Metastatises+1 more
Sichuan University 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07789912
What this trial is testing

BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies

Who this might be right for
Leptomeningeal MetastasisBreast CancerLung Cancer (NSCLC)
University of Miami 40
Testing effectiveness (Phase 2)Study completedNCT06376292
What this trial is testing

A Prospective Single Arm Phase II Exploratory Study on the Combination of Whole Brain Radiotherapy, Thiotepa Intrathecal Injection and Systemic Treatment of Primary Diseases in the Treatment of Solid Tumor Leptomeningeal Metastasis

Who this might be right for
Solid Tumor Leptomeningeal Metastasis
Second Affiliated Hospital, Zhejiang University, School of Medicine 58
Testing effectiveness (Phase 2)Ended earlyNCT04729348
What this trial is testing

Pembrolizumab And Lenvatinib In Leptomeningeal Metastases

Who this might be right for
Solid TumorSolid Tumor, AdultLeptomeningeal Metastasis
Massachusetts General Hospital 10
Testing effectiveness (Phase 2)Study completedNCT03507244
What this trial is testing

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 34
Not applicableLooking for participantsNCT07476781
What this trial is testing

Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study

Who this might be right for
Solid Tumor MalignanciesBrain MetastasasesLeptomeningeal Disease (LMD)+1 more
Sunnybrook Health Sciences Centre 60