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Results for “Solid Tumors With IDH1 Mutation”

12 trials

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Showing 12 of 12 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Early research (Phase 1)Ended earlyNCT05814536
What this trial is testing

IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor

Who this might be right for
Cholangiocarcinoma With IDH1 MutationSolid Tumors With IDH1 Mutation
AnHeart Therapeutics Inc. 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT03212274
What this trial is testing

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
Advanced Malignant Solid NeoplasmGlioblastomaRecurrent Cholangiocarcinoma+4 more
National Cancer Institute (NCI) 89
Early research (Phase 1)Study completedNCT02073994
What this trial is testing

Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation

Who this might be right for
CholangiocarcinomaChondrosarcomaGlioma+1 more
Institut de Recherches Internationales Servier 174
Early research (Phase 1)Ended earlyNCT02576665
What this trial is testing

Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)

Who this might be right for
Colorectal CancerTriple Negative Breast CancerPancreatic Cancer+9 more
Tocagen Inc. 21
Early research (Phase 1)Active Not RecruitingNCT04521686
What this trial is testing

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
CholangiocarcinomaChondrosarcomaGlioma+1 more
Eli Lilly and Company 200
Early research (Phase 1)Active Not RecruitingNCT02381886
What this trial is testing

IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Who this might be right for
Advanced Malignancies That Harbor IDHR132 Mutations
Novartis Pharmaceuticals 166
Early research (Phase 1)Study completedNCT02071862
What this trial is testing

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Who this might be right for
Solid TumorsTriple-Negative Breast CancerNon Small Cell Lung Cancer+7 more
Calithera Biosciences, Inc 210
Testing effectiveness (Phase 2)Study completedNCT04056910
What this trial is testing

Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors

Who this might be right for
Advanced Solid TumorIDH1 MutationGlioma
Jason J. Luke, MD 15
Testing effectiveness (Phase 2)Study completedNCT03684811
What this trial is testing

FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Who this might be right for
Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme)Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas)Cohort 3a and 3b: Chondrosarcoma+2 more
Forma Therapeutics, Inc.
Early research (Phase 1)Study completedNCT02481154
What this trial is testing

Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

Who this might be right for
Glioma
Institut de Recherches Internationales Servier 95
Testing effectiveness (Phase 2)Study completedNCT02496741
What this trial is testing

Metformin And Chloroquine in IDH1/2-mutated Solid Tumors

Who this might be right for
GliomaCholangiocarcinomaChondrosarcoma
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15
93