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Results for “Somatic Mutation”

81 trials

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Showing 20 of 81 results

Not applicableStudy completedNCT02827357
What this trial is testing

Responses to Chemotherapy of Patients With Non-small Cell Lung Cancer Harboring a Known Somatic Activating HER2 Mutation

Who this might be right for
Lung Cancer
University Hospital, Toulouse 101
Testing effectiveness (Phase 2)Study completedNCT02789332
What this trial is testing

Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency

Who this might be right for
Breast CancerTriple Negative Breast NeoplasmsHRpos Breast Neoplasms+1 more
GBG Forschungs GmbH 107
Not applicableLooking for participantsNCT02288676
What this trial is testing

DOvEEgene/WISE Genomics: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsEndometrial Cancer+6 more
McGill University 1,200
Testing effectiveness (Phase 2)Ended earlyNCT02595840
What this trial is testing

Biomarker Study Accompanying the AIO-TRK-0114 Study (MARBLE)

Who this might be right for
Non-small-cell Lung Cancer With Somatic EGFR Mutations
Universität Duisburg-Essen 4
Not applicableEnrolling By InvitationNCT03901521
What this trial is testing

Autosomal Dominant Polycystic Kidney Disease Somatic Mutation Biorepository

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Weill Medical College of Cornell University 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT03344965
What this trial is testing

Olaparib In Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerInvasive Breast CancerSomatic Mutation Breast Cancer (BRCA1)+7 more
Beth Israel Deaconess Medical Center 114
Not applicableLooking for participantsNCT06425146
What this trial is testing

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)

Who this might be right for
Oral Squamous Cell Carcinomas
Centre Leon Berard 30
Not applicableStudy completedNCT04314245
What this trial is testing

Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for the Detection of Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaBladder Cancer
AnchorDx Medical Co., Ltd. 1,170
Testing effectiveness (Phase 2)WithdrawnNCT05512182
What this trial is testing

Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Family (EGFR, HER2, HER3, HER4) Mutations or HER2 Amplification/Overexpression

Who this might be right for
Recurrent/Advanced Gastric Cancer
Yonsei University
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Not applicableLooking for participantsNCT05512169
What this trial is testing

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia

Who this might be right for
ALL, ChildhoodPediatric CancerToxicity, Drug+5 more
University of Geneva, Switzerland 556
Not applicableStudy completedNCT06861647
What this trial is testing

ISITE: Investigation of Somatic Alterations in Tumours of the Eye

Who this might be right for
Somatic MutationOcular Melanoma
The Wellcome Sanger Institute 58
Not applicableUnknownNCT03301961
What this trial is testing

Multiplex Analysis of Circulating Tumor DNA

Who this might be right for
CarcinomaNon-small-cell Lung CancerLung Neoplasm
Peking University People's Hospital 400
Not applicableStudy completedNCT04253106
What this trial is testing

Liquid Biopsies for the Personalized Management of Patients with Hereditary Diffuse Gastric Cancer

Who this might be right for
Hereditary Diffuse Gastric Cancer
Assistance Publique - Hôpitaux de Paris 16
Not applicableStudy completedNCT02626039
What this trial is testing

Characterization & Comparison of Drugable Mutations in Primary and Metastatic Tumors, CTCs and cfDNA in MBCpatients

Who this might be right for
Metastatic Breast Cancer
Hospital General Universitario Gregorio Marañon 40
Testing effectiveness (Phase 2)Study completedNCT04493060
What this trial is testing

Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
Mayo Clinic 22
Post-approval studies (Phase 4)Study completedNCT02476968
What this trial is testing

To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer

Who this might be right for
BRCA or HRR+ Mutated Ovarian Cancer Patients
AstraZeneca 181
Not applicableLooking for participantsNCT06357845
What this trial is testing

Linking Somatic Mutation Rate With Baseline Exposure in East Palestine

Who this might be right for
Somatic Mutation
Case Comprehensive Cancer Center 500
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+21 more
Masonic Cancer Center, University of Minnesota 70
Not applicableWithdrawnNCT01372696
What this trial is testing

Endoscopic Characteristics of Colonic Tumours

Who this might be right for
Colonic PolypColon Cancer
Professor Michael Bourke
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