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Results for “Somatic Mutation”

82 trials

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Showing 20 of 82 results

Not applicableLooking for participantsNCT05364294
What this trial is testing

Molecular Diagnosis of Systemic Autoinflammatory Diseases

Who this might be right for
Inflammatory DiseaseGenetic DiseaseSomatic Mutation+2 more
Institut National de la Santé Et de la Recherche Médicale, France 300
Not applicableStudy completedNCT02827357
What this trial is testing

Responses to Chemotherapy of Patients With Non-small Cell Lung Cancer Harboring a Known Somatic Activating HER2 Mutation

Who this might be right for
Lung Cancer
University Hospital, Toulouse 101
Not applicableStudy completedNCT01556399
What this trial is testing

Endoscopic Characteristics of Duodenal and Ampullary Lesions

Who this might be right for
Duodenal Diseases
Professor Michael Bourke 350
Testing effectiveness (Phase 2)Ended earlyNCT02595840
What this trial is testing

Biomarker Study Accompanying the AIO-TRK-0114 Study (MARBLE)

Who this might be right for
Non-small-cell Lung Cancer With Somatic EGFR Mutations
Universität Duisburg-Essen 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04579380
What this trial is testing

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Who this might be right for
Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more
Seagen, a wholly owned subsidiary of Pfizer 217
Testing effectiveness (Phase 2)Ended earlyNCT04171700
What this trial is testing

Evaluate Rucaparib in Participants With Solid Tumors and With Deleterious Mutations in HRR Genes

Who this might be right for
Solid Tumor
pharmaand GmbH 83
Not applicableWithdrawnNCT01372696
What this trial is testing

Endoscopic Characteristics of Colonic Tumours

Who this might be right for
Colonic PolypColon Cancer
Professor Michael Bourke
Not applicableNot Yet RecruitingNCT06895681
What this trial is testing

UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

Who this might be right for
Solid TumorSolid Tumor, AdultSomatic Mutation+2 more
University of California, San Francisco 50,000
Testing effectiveness (Phase 2)Ended earlyNCT01953926
What this trial is testing

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

Who this might be right for
Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Puma Biotechnology, Inc. 582
Not applicableLooking for participantsNCT06494358
What this trial is testing

Liquid Biopsies for the Detection of Somatic Mutations in bAVMs

Who this might be right for
Brain Arterial Disease
Assistance Publique - Hôpitaux de Paris 50
Testing effectiveness (Phase 2)Ended earlyNCT04390243
What this trial is testing

Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation

Who this might be right for
Locally Advanced Pancreatic CarcinomaMetastatic Pancreatic CarcinomaRecurrent Pancreatic Carcinoma+2 more
Academic and Community Cancer Research United 6
Testing effectiveness (Phase 2)Study completedNCT02789332
What this trial is testing

Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency

Who this might be right for
Breast CancerTriple Negative Breast NeoplasmsHRpos Breast Neoplasms+1 more
GBG Forschungs GmbH 107
Not applicableStudy completedNCT02075307
What this trial is testing

Effect of Blueberry Consumption on Metabolic Syndrome & DNA Damage

Who this might be right for
Metabolic SyndromeInsulin ResistanceDNA Damage
UCSF Benioff Children's Hospital Oakland 7
Not applicableLooking for participantsNCT01994057
What this trial is testing

A Retrospective Study of EGFR-TKIs,Gefitinib, Erlotinib and Osimertinib in NSCLC Patients Treatment

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)EGFR-TKI Resistant MutationEGFR-TKI Sensitizing Mutation+2 more
Sun Yat-sen University 1,000
Early research (Phase 1)Looking for participantsNCT04890613
What this trial is testing

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Who this might be right for
Advanced Solid Tumor
Senhwa Biosciences, Inc. 52
Testing effectiveness (Phase 2)UnknownNCT04940637
What this trial is testing

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC

Who this might be right for
Lung CancerMesothelioma
University of Turin, Italy 70
Not applicableLooking for participantsNCT06194669
What this trial is testing

Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells

Who this might be right for
Carcinoma, Renal CellVon Hippel-Lindau Disease
IRCCS San Raffaele 50
Not applicableEnrolling By InvitationNCT06656767
What this trial is testing

Somatic Mutation in Chronic Liver Disease

Who this might be right for
Chronic Liver DiseaseSomatic Mutation
The Wellcome Sanger Institute 250
Testing effectiveness (Phase 2)Ended earlyNCT03140670
What this trial is testing

Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy

Who this might be right for
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine 46
Not applicableUnknownNCT06425146
What this trial is testing

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)

Who this might be right for
Oral Squamous Cell Carcinomas
Centre Leon Berard 30
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