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Results for “Spastic Paraplegia”

75 trials

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Showing 20 of 75 results

Early research (Phase 1)Active Not RecruitingNCT06069687
What this trial is testing

Administration of MELPIDA to Determine the Safety and Efficacy for Patients With Spastic Paraplegia Type 50

Who this might be right for
Spastic Paraplegia Type 50
The Hospital for Sick Children 1
Not applicableStudy completedNCT00015444
What this trial is testing

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

Who this might be right for
Primary Lateral Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS) 189
Not applicableActive Not RecruitingNCT02327845
What this trial is testing

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal DementiaPrimary Lateral Sclerosis+3 more
University of Miami 708
Not applicableStudy completedNCT05613114
What this trial is testing

Effect of Dalfampridine in Patients With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
European University of Lefke 8
Not applicableStudy completedNCT00677768
What this trial is testing

Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)

Who this might be right for
Amyotrophic Lateral SclerosisLou Gehrig's DiseasePrimary Lateral Sclerosis+2 more
Massachusetts General Hospital 475
Large-scale testing (Phase 3)Study completedNCT02604186
What this trial is testing

Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic Paraplegia
University of Campinas, Brazil 55
Testing effectiveness (Phase 2)Ended earlyNCT05394064
What this trial is testing

Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)

Who this might be right for
AMNAMN Gene MutationX-ALD
SwanBio Therapeutics, Inc. 9
Not applicableStudy completedNCT07706517
What this trial is testing

Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood

Who this might be right for
Spina BifidaCerebral PalsySpinal Cord Injury+2 more
Centre Hospitalier Universitaire de Saint Etienne 128
Not applicableLooking for participantsNCT04712812
What this trial is testing

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

Who this might be right for
Hereditary Spastic ParaplegiaSPG47SPG50+8 more
Boston Children's Hospital 700
Not applicableLooking for participantsNCT06156813
What this trial is testing

Turkish Lower-Extremity Motor Activity Log (LE-MAL)

Who this might be right for
StrokeSpastic Paraplegia
Gaziantep Islam Science and Technology University 80
Testing effectiveness (Phase 2)Study completedNCT02188277
What this trial is testing

Treatment With Xeomin Versus Botox in Children With Spastic Equine and Equinovarus Foot Deformation in Pediatric Cerebral Palsy

Who this might be right for
Cerebral PalsySpastic Paraplegia and HemiparesisEquine and Equinovarus Foot Deformation
Merz Pharmaceuticals GmbH 64
Not applicableStudy completedNCT00136630
What this trial is testing

Natural History, Genetic Bases and Phenotype-genotype Correlations in Autosomal Dominant Spinocerebellar Degenerations

Who this might be right for
Spinocerebellar AtaxiasSpastic Paraplegias
Institut National de la Santé Et de la Recherche Médicale, France 175
Not applicableLooking for participantsNCT06261424
What this trial is testing

Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

Who this might be right for
Autosomal Recessive Spastic Ataxia of Charlevoix-SaguenaySpastic Paraplegia 7
Laval University 84
Not applicableStudy completedNCT00140829
What this trial is testing

SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias

Who this might be right for
Cerebellar AtaxiasSpastic Paraplegias
Institut National de la Santé Et de la Recherche Médicale, France 6,000
Testing effectiveness (Phase 2)Study completedNCT01349478
What this trial is testing

The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI)

Who this might be right for
Motor Complete Spinal Cord Injury
Dr. Gabriel Zeilig 11
Not applicableStudy completedNCT00001156
What this trial is testing

Assessment of Patients With Multiple Sclerosis (MS)

Who this might be right for
Herpesviridae InfectionHTLV-I InfectionMultiple Sclerosis+2 more
National Institute of Neurological Disorders and Stroke (NINDS) 1,388
Not applicableStudy completedNCT03104088
What this trial is testing

Studying Cognition in SPG4

Who this might be right for
Cognitive ImpairmentHereditary Spastic Paraplegia
University Hospital Tuebingen 50
Not applicableLooking for participantsNCT07136844
What this trial is testing

Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology

Who this might be right for
Neuromuscular DiseasesObesity (Disorder)Myotonic Dystrophy 1+9 more
Centre Hospitalier Universitaire de Liege 300
Not applicableStudy completedNCT01815814
What this trial is testing

Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy

Who this might be right for
Spastic Cerebral Palsy
Stanford University 38
Testing effectiveness (Phase 2)Looking for participantsNCT05518188
What this trial is testing

Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Who this might be right for
Spasticity, MuscleMicrocephalyIntellectual Deficiency+3 more
Elpida Therapeutics SPC 4
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