Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Squamous Cell Carcinoma of Unknown Primary”

58 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 58 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04862650
What this trial is testing

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+22 more
Marcelo Bonomi 46
Not applicableStudy completedNCT00900302
What this trial is testing

OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer

Who this might be right for
Cancer
OHSU Knight Cancer Institute 98
Testing effectiveness (Phase 2)Study completedNCT00003582
What this trial is testing

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

Who this might be right for
Carcinoma of Unknown PrimaryHead and Neck Cancer
University of Miami 36
Not applicableStudy completedNCT02112344
What this trial is testing

Intensity-modulated Radiotherapy in Patients With Squamous Cell Carcinoma of Unknown Primary (SCCUP) of the Head and Neck

Who this might be right for
Head and Neck Cancer
Royal Marsden NHS Foundation Trust 19
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Not applicableStudy completedNCT00656760
What this trial is testing

PET/CT: Role in Detecting Unknown Primary Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
University of Calgary 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT05075980
What this trial is testing

Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study

Who this might be right for
Head and Neck CarcinomaHead and Neck Carcinoma of Unknown PrimaryHypopharyngeal Carcinoma+9 more
Mayo Clinic 174
Not applicableActive Not RecruitingNCT05904327
What this trial is testing

Circulating Biomarkers in Oropharyngeal Cancers

Who this might be right for
Oropharynx Squamous Cell CarcinomaOropharynx CancerTonsillar Cancer+1 more
Region Örebro County 130
Large-scale testing (Phase 3)Looking for participantsNCT06589804
What this trial is testing

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell CarcinomaMetastatic Laryngeal Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI) 158
Large-scale testing (Phase 3)Study completedNCT03258554
What this trial is testing

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI) 196
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT06995508
What this trial is testing

Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO Trial

Who this might be right for
Cancer-Associated AnorexiaHead and Neck Squamous Cell CarcinomaNeck Squamous Cell Carcinoma of Unknown Primary
Roswell Park Cancer Institute 66
Large-scale testing (Phase 3)UnknownNCT00022178
What this trial is testing

Combination Chemotherapy in Treating Patients With Metastatic Cancer of an Unknown Site of Origin

Who this might be right for
Carcinoma of Unknown Primary
The Christie NHS Foundation Trust
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06578871
What this trial is testing

Surgery and Reducing Ionizing Radiation of the Unknown Primary

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 90
Not applicableActive Not RecruitingNCT04151134
What this trial is testing

Evaluation of Tongue Base MucOsectomy & Step sErial Sectioning

Who this might be right for
Squamous Cell Carcinoma of the Oropharynx
Royal Marsden NHS Foundation Trust 100
Testing effectiveness (Phase 2)Study completedNCT03422536
What this trial is testing

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Basaloid CarcinomaRecurrent Head and Neck Squamous Cell CarcinomaRecurrent Oropharyngeal Squamous Cell Carcinoma+21 more
University of Arizona 78
Testing effectiveness (Phase 2)Active Not RecruitingNCT02721732
What this trial is testing

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Who this might be right for
Advanced Malignant Solid NeoplasmCarcinoma of Unknown PrimaryMetastatic Adrenal Gland Pheochromocytoma+16 more
M.D. Anderson Cancer Center 157
Testing effectiveness (Phase 2)Looking for participantsNCT06636734
What this trial is testing

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more
Emory University
Early research (Phase 1)Looking for participantsNCT05172245
What this trial is testing

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Carcinoma of Unknown Primary+24 more
National Cancer Institute (NCI)
Not applicableActive Not RecruitingNCT04584008
What this trial is testing

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics

Who this might be right for
Biliary Tract NeoplasmsGastric CancerEsophageal Squamous Cell Carcinoma+6 more
Peking University 600
Next Page
40
28
46