Early research (Phase 1)Study completedNCT00004178What this trial is testingGene Therapy in Treating Patients With CancerWho this might be right forCancer Roger Williams Medical Center
Testing effectiveness (Phase 2)Looking for participantsNCT05576974What this trial is testingA Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)Who this might be right forHead and Neck CancerUnknown Primary CancerHead and Neck Squamous Cell Carcinoma University of Texas Southwestern Medical Center 120
Early research (Phase 1)Study completedNCT00014456What this trial is testingCombination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid TumorsWho this might be right forBladder CancerBreast CancerCarcinoma of Unknown Primary+9 more Dartmouth-Hitchcock Medical Center 35
Not applicableEnded earlyNCT01077869What this trial is testingA Feasibility Study on the Use of F-18-FDG-PET and Optical Imaging in Evaluation of Radiation-induced Oral MucositisWho this might be right forSquamous Cell Carcinoma of the Oral CavityOropharynx MetastasesLymph Metastases University Hospital, Ghent 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876What this trial is testingEfficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing TumorsWho this might be right forMSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more SOLTI Breast Cancer Research Group 184
Early research (Phase 1)Looking for participantsNCT04754321What this trial is testingCombining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck CancerWho this might be right forHead and Neck Carcinoma of Unknown PrimaryLocally Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell Carcinoma+3 more Ohio State University Comprehensive Cancer Center 45
Not applicableStudy completedNCT03281499What this trial is testingTransoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck CancerWho this might be right forHead and Neck Squamous Cell Carcinoma University Health Network, Toronto 22
Testing effectiveness (Phase 2)Looking for participantsNCT05544136What this trial is testingDecreasing Radiation Therapy and Chemotherapy in People With Head and Neck CancerWho this might be right forHead and Neck CancerHead and Neck CarcinomaHead and Neck Neoplasms+1 more Memorial Sloan Kettering Cancer Center 12
Not applicableStudy completedNCT02628379What this trial is testingOutcomes of FoundationOne Directed Therapy in Cancer of Unknown PrimaryWho this might be right forNeoplasms, Unknown PrimaryCUPMetastatic Disease+3 more Foundation Medicine 125
Testing effectiveness (Phase 2)Study completedNCT00006361What this trial is testingSU5416 in Treating Patients With Advanced or Recurrent Cancer of the Head and NeckWho this might be right forCarcinoma of Unknown PrimaryHead and Neck CancerNon-melanomatous Skin Cancer Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Looking for participantsNCT07217028What this trial is testingStudy Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell CarcinomaWho this might be right forSCC - Squamous Cell CarcinomaRadiotracerHead and Neck Squamous Cell Carcinoma+1 more Vanderbilt-Ingram Cancer Center 25
Not applicableUnknownNCT03896958What this trial is testingThe PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)Who this might be right forCancer, All TypesCancer of LiverCancer of Stomach+42 more SpeciCare 1,000
Very early researchActive Not RecruitingNCT05245682What this trial is testingTolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck CancerWho this might be right forHead and Neck Carcinoma of Unknown PrimaryLocally Advanced Head and Neck Squamous Cell CarcinomaLocally Advanced Hypopharyngeal Squamous Cell Carcinoma+3 more Emory University 10
Not applicableStudy completedNCT00530283What this trial is testingPET-CT for Squamous Cell Carcinoma (SCC) of the Neck Nodes Unknown Primary MalignancyWho this might be right forSquamous Cell Cancer AHS Cancer Control Alberta 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02978625What this trial is testingTalimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin CancersWho this might be right forAnaplastic Large Cell Lymphoma, ALK-NegativeAnaplastic Large Cell Lymphoma, ALK-PositiveApocrine Carcinoma+36 more National Cancer Institute (NCI) 68
Not applicableStudy completedNCT06112535What this trial is testingProspective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic SurgeryWho this might be right forSquamous Cell Carcinoma of the OropharynxSquamous Cell Carcinoma, Unknown Primary CMR Surgical Ltd 60
Not applicableStudy completedNCT05841966What this trial is testingSurgeon-performed Intraoperative Transoral Ultrasound for Cancer of Unknown PrimaryWho this might be right forCancer of Unknown Primary SiteUnknown Primary CancerUnknown Primary, Squamous Cell Carcinoma Rigshospitalet, Denmark 30
Testing effectiveness (Phase 2)Study completedNCT00003657What this trial is testingHigh-dose ICE With AmifostineWho this might be right forBladder CancerBrain and Central Nervous System TumorsCarcinoma of Unknown Primary+8 more Dana-Farber Cancer Institute 24
Large-scale testing (Phase 3)Study completedNCT00002507What this trial is testingRadiation Therapy and Chemotherapy in Treating Patients With Head and Neck CancerWho this might be right forCarcinoma of Unknown PrimaryHead and Neck Cancer Yale University
Testing effectiveness (Phase 2)Ended earlyNCT05110781What this trial is testingAtezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary SiteWho this might be right forLocally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckResectable Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 University of California, Davis 1