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Results for “Stage III (Unresectable) or Stage IV Advanced Melanoma”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Ended earlyNCT00104884
What this trial is testing

FR901228 in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma

Who this might be right for
Malignant MelanomaMelanoma
ECOG-ACRIN Cancer Research Group 4
Large-scale testing (Phase 3)Study completedNCT00110019
What this trial is testing

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Mucosal MelanomaRecurrent MelanomaStage IIIA Skin Melanoma+3 more
National Cancer Institute (NCI) 823
Testing effectiveness (Phase 2)Study completedNCT00003989
What this trial is testing

ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma

Who this might be right for
Lung CancerMelanoma (Skin)
European Organisation for Research and Treatment of Cancer - EORTC 50
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT01433991
What this trial is testing

E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Participants With Recurrent Glioblastoma or Unresectable Stage III or Stage IV Melanoma After Prior Systemic Therapy (Expansion Cohort and Phase 2)

Who this might be right for
Advanced Solid Tumors
Eisai Inc. 30
Not applicableNo Longer AvailableNCT02142218
What this trial is testing

Expanded Access Program With Nivolumab to Treat Melanoma

Who this might be right for
Stage III (Unresectable) or Stage IV Advanced Melanoma
Bristol-Myers Squibb
Large-scale testing (Phase 3)Active Not RecruitingNCT04657991
What this trial is testing

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Pfizer 257
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Large-scale testing (Phase 3)Active Not RecruitingNCT02224781
What this trial is testing

Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Melanoma+2 more
National Cancer Institute (NCI) 267
Not applicableNo Longer AvailableNCT02416232
What this trial is testing

Access Study of Trametinib for Subjects With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma

Who this might be right for
Melanoma
GlaxoSmithKline
Large-scale testing (Phase 3)Active Not RecruitingNCT05352672
What this trial is testing

Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Regeneron Pharmaceuticals 1,546
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Large-scale testing (Phase 3)Active Not RecruitingNCT02339571
What this trial is testing

A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

Who this might be right for
Stage III Cutaneous Melanoma AJCC v7Stage IV Cutaneous Melanoma AJCC v6 and v7
National Cancer Institute (NCI) 600
Testing effectiveness (Phase 2)Looking for participantsNCT05655312
What this trial is testing

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

Who this might be right for
Recurrent Melanoma (Skin)Metastatic MelanomaMelanoma Stage IV+1 more
Perspective Therapeutics 300
Testing effectiveness (Phase 2)WithdrawnNCT02452281
What this trial is testing

Pilot Study to Evaluate the Effects of a Vaccine (HSPPC-96) Combined With Ipilimumab in Patients With Advanced Melanoma

Who this might be right for
Melanoma
Rabih Said
Large-scale testing (Phase 3)Study completedNCT02599402
What this trial is testing

Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma

Who this might be right for
Melanoma
Bristol-Myers Squibb 533
Testing effectiveness (Phase 2)Ended earlyNCT02410863
What this trial is testing

Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanoma

Who this might be right for
Malignant Melanoma
Prof. Dr. med. Dirk Schadendorf 10
Testing effectiveness (Phase 2)Study completedNCT00072345
What this trial is testing

Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma

Who this might be right for
Intraocular MelanomaMelanoma (Skin)
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Ended earlyNCT02419495
What this trial is testing

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+26 more
M.D. Anderson Cancer Center 221
Testing effectiveness (Phase 2)Ended earlyNCT06984328
What this trial is testing

Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)

Who this might be right for
Cutaneous MelanomaRelapsed/Refractory, Locally Advanced Unresectable Melanoma (Stage IIIB, IIIC, or IIID)Metastatic Cutaneous Melanoma (Stage IV)
Genmab 1
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