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Results for “Stage III Bladder Cancer American Joint Committee on Cancer ( AJCC) v8”

32 trials

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Showing 20 of 32 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT03375307
What this trial is testing

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

Who this might be right for
Advanced Bladder CarcinomaAdvanced Genitourinary System CarcinomaMetastatic Bladder Carcinoma+3 more
National Cancer Institute (NCI) 60
Testing effectiveness (Phase 2)Looking for participantsNCT06263153
What this trial is testing

Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy

Who this might be right for
Bladder Urothelial CarcinomaMuscle Invasive Bladder CarcinomaStage II Bladder Cancer AJCC v8+1 more
Yuanquan Yang 24
Early research (Phase 1)Study completedNCT04164069
What this trial is testing

Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab

Who this might be right for
Advanced Colorectal CarcinomaMetastatic Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8+13 more
Anne Noonan 9
Not applicableLooking for participantsNCT06350734
What this trial is testing

Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study

Who this might be right for
Stage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8Stage I Bladder Cancer AJCC v8+2 more
Mayo Clinic 704
Post-approval studies (Phase 4)Looking for participantsNCT06764095
What this trial is testing

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis and Ureter Urothelial CarcinomaMetastatic Bladder Urothelial Carcinoma+4 more
Mayo Clinic 75
Large-scale testing (Phase 3)Looking for participantsNCT07097142
What this trial is testing

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

Who this might be right for
Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
NRG Oncology 486
Not applicableLooking for participantsNCT06414317
What this trial is testing

An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers

Who this might be right for
Locally Advanced Bladder CarcinomaMetastatic Bladder CarcinomaStage III Bladder Cancer AJCC v8+2 more
Roswell Park Cancer Institute 160
Testing effectiveness (Phase 2)WithdrawnNCT05564416
What this trial is testing

Testing Anti-Cancer Drugs Erdafitinib With or Without Atezolizumab in Patients With Localized Bladder Cancer Not Able to Receive Cisplatin Chemotherapy, NERA Trial

Who this might be right for
Bladder CarcinomaBladder Urothelial CarcinomaMuscle Invasive Bladder Carcinoma+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT04216290
What this trial is testing

Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Who this might be right for
Bladder Urothelial CarcinomaStage III Bladder Cancer AJCC v8
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07332351
What this trial is testing

Neoadjuvant Intravesical Nadofaragene Firadenovec With Gemcitabine, Cisplatin and Durvalumab for the Treatment of Muscle Invasive Bladder Cancer, TRIFECTA Trial

Who this might be right for
Muscle Invasive Bladder Urothelial CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
University of Washington 33
Testing effectiveness (Phase 2)Study completedNCT03513952
What this trial is testing

Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma

Who this might be right for
Advanced Bladder Urothelial CarcinomaAdvanced Ureter Urothelial CarcinomaMetastatic Bladder Urothelial Carcinoma+21 more
National Cancer Institute (NCI) 47
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT04953104
What this trial is testing

ARID1A and/or KDM6A Mutation and CXCL13 Expression

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+29 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT05581589
What this trial is testing

Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer

Who this might be right for
Muscle Invasive Bladder CarcinomaStage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8
University of Washington 18
Early research (Phase 1)Active Not RecruitingNCT04963153
What this trial is testing

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+17 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Active Not RecruitingNCT03582475
What this trial is testing

Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate

Who this might be right for
Bladder Small Cell Neuroendocrine CarcinomaCastration-Resistant Prostate CarcinomaMetastatic Bladder Urothelial Carcinoma+14 more
Jonsson Comprehensive Cancer Center 15
Testing effectiveness (Phase 2)Study completedNCT03617913
What this trial is testing

Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer

Who this might be right for
Bladder Carcinoma Infiltrating the Muscle of the Bladder WallStage II Bladder Cancer AJCC v8Stage II Renal Pelvis Cancer AJCC v8+9 more
Mayo Clinic 2
Testing effectiveness (Phase 2)Looking for participantsNCT05756569
What this trial is testing

Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology

Who this might be right for
Bladder Squamous Cell CarcinomaLocally Advanced Bladder CarcinomaMalignant Renal Pelvis Neoplasm+8 more
Emory University 25
Testing effectiveness (Phase 2)Study completedNCT04383743
What this trial is testing

Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer

Who this might be right for
Stage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8Muscle Invasive Bladder Carcinoma
University of Washington 17
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