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Results for “Stage III Intrahepatic Cholangiocarcinoma”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)WithdrawnNCT02856568
What this trial is testing

Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma

Who this might be right for
Non-Resectable CholangiocarcinomaRecurrent CholangiocarcinomaStage III Extrahepatic Bile Duct Cancer+10 more
Mayo Clinic
Large-scale testing (Phase 3)Study completedNCT01313377
What this trial is testing

Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
UNICANCER 190
Early research (Phase 1)Study completedNCT01825603
What this trial is testing

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Who this might be right for
Ampulla of Vater AdenocarcinomaGallbladder AdenocarcinomaMetastatic Pancreatic Adenocarcinoma+17 more
University of Nebraska 17
Testing effectiveness (Phase 2)WithdrawnNCT05514912
What this trial is testing

Preoperative Nab-paclitaxel, Cisplatin, and Gemcitabine Chemotherapy With or Without Infigratinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, The OPTIC Trial

Who this might be right for
Resectable Intrahepatic CholangiocarcinomaStage 0 Intrahepatic Cholangiocarcinoma AJCC v8Stage I Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Emory University
Large-scale testing (Phase 3)Ended earlyNCT04163900
What this trial is testing

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
NuCana plc 773
Large-scale testing (Phase 3)WithdrawnNCT03081039
What this trial is testing

Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Patients With Resected or Ablation Intra-Hepatic Cholangiocarcinoma

Who this might be right for
Intrahepatic Cholangiocarcinoma
University of Louisville
Testing effectiveness (Phase 2)Study completedNCT04072445
What this trial is testing

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Gallbladder CarcinomaRefractory Bile Duct Carcinoma+15 more
Mayo Clinic 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT05564403
What this trial is testing

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Gallbladder CarcinomaAdvanced Intrahepatic Cholangiocarcinoma+14 more
National Cancer Institute (NCI) 66
Large-scale testing (Phase 3)Study completedNCT03768414
What this trial is testing

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Who this might be right for
Stage III Distal Bile Duct Cancer AJCC v8Stage III Gallbladder Cancer AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8+14 more
SWOG Cancer Research Network 452
Testing effectiveness (Phase 2)Active Not RecruitingNCT04251715
What this trial is testing

MFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Who this might be right for
Liver and Intrahepatic Bile Duct CarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8+3 more
OHSU Knight Cancer Institute 5
Testing effectiveness (Phase 2)Study completedNCT03201458
What this trial is testing

Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer

Who this might be right for
Gallbladder CarcinomaMetastatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
National Cancer Institute (NCI) 86
Early research (Phase 1)Ended earlyNCT06420349
What this trial is testing

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Who this might be right for
Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRefractory Cholangiocarcinoma+4 more
Mayo Clinic 7
Early research (Phase 1)Active Not RecruitingNCT04491942
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical Carcinoma+31 more
National Cancer Institute (NCI) 74
Large-scale testing (Phase 3)Ended earlyNCT00658593
What this trial is testing

Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
NCIC Clinical Trials Group 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT04175912
What this trial is testing

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Who this might be right for
Metastatic CholangiocarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+12 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Study completedNCT02520141
What this trial is testing

Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

Who this might be right for
CholangiocarcinomaLiver and Intrahepatic Bile Duct CarcinomaStage III Gallbladder Cancer AJCC v7+9 more
M.D. Anderson Cancer Center 61
Testing effectiveness (Phase 2)Looking for participantsNCT03942328
What this trial is testing

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+3 more
Mayo Clinic
Early research (Phase 1)Looking for participantsNCT06058663
What this trial is testing

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaOligometastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Mayo Clinic 16
Large-scale testing (Phase 3)Looking for participantsNCT05342194
What this trial is testing

Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shanghai Junshi Bioscience Co., Ltd. 480
Testing effectiveness (Phase 2)Study completedNCT03579771
What this trial is testing

Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer

Who this might be right for
Resectable CholangiocarcinomaStage IB Intrahepatic Cholangiocarcinoma AJCC v8Stage II Intrahepatic Cholangiocarcinoma AJCC v8+3 more
Emory University 30
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