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Results for “Stage III Intrahepatic Cholangiocarcinoma”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Study completedNCT03579771
What this trial is testing

Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer

Who this might be right for
Resectable CholangiocarcinomaStage IB Intrahepatic Cholangiocarcinoma AJCC v8Stage II Intrahepatic Cholangiocarcinoma AJCC v8+3 more
Emory University 30
Early research (Phase 1)Study completedNCT01825603
What this trial is testing

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Who this might be right for
Ampulla of Vater AdenocarcinomaGallbladder AdenocarcinomaMetastatic Pancreatic Adenocarcinoma+17 more
University of Nebraska 17
Large-scale testing (Phase 3)Looking for participantsNCT05342194
What this trial is testing

Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shanghai Junshi Bioscience Co., Ltd. 480
Large-scale testing (Phase 3)Not Yet RecruitingNCT07328919
What this trial is testing

Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations

Who this might be right for
Intrahepatic Cholangiocarcinoma (Icc)Advanced Cholangiocarcinoma
TransThera Sciences (Nanjing), Inc. 138
Early research (Phase 1)Looking for participantsNCT06058663
What this trial is testing

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaOligometastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Mayo Clinic 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT05564403
What this trial is testing

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Gallbladder CarcinomaAdvanced Intrahepatic Cholangiocarcinoma+14 more
National Cancer Institute (NCI) 66
Early research (Phase 1)Active Not RecruitingNCT04491942
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical Carcinoma+31 more
National Cancer Institute (NCI) 74
Large-scale testing (Phase 3)WithdrawnNCT03081039
What this trial is testing

Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Patients With Resected or Ablation Intra-Hepatic Cholangiocarcinoma

Who this might be right for
Intrahepatic Cholangiocarcinoma
University of Louisville
Large-scale testing (Phase 3)Ended earlyNCT02200042
What this trial is testing

Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer

Who this might be right for
Stage III Intrahepatic CholangiocarcinomaStage IVA Intrahepatic Cholangiocarcinoma
NRG Oncology 1
Testing effectiveness (Phase 2)Study completedNCT03201458
What this trial is testing

Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer

Who this might be right for
Gallbladder CarcinomaMetastatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Study completedNCT04264260
What this trial is testing

Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment

Who this might be right for
Hepatocellular Carcinoma Stage IIIBCholangiocarcinoma, IntrahepaticCholangiocarcinoma; With Hepatocellular Carcinoma+1 more
Kaohsiung Medical University Chung-Ho Memorial Hospital 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT06178588
What this trial is testing

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

Who this might be right for
Locally Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRecurrent Cholangiocarcinoma+4 more
University of Kansas Medical Center 15
Testing effectiveness (Phase 2)Ended earlyNCT04251715
What this trial is testing

MFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Who this might be right for
Liver and Intrahepatic Bile Duct CarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8+3 more
OHSU Knight Cancer Institute 5
Large-scale testing (Phase 3)Not Yet RecruitingNCT07765433
What this trial is testing

Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer

Who this might be right for
Locally Advanced Biliary Tract AdenocarcinomaLocally Advanced Extrahepatic CholangiocarcinomaLocally Advanced Intrahepatic Cholangiocarcinoma+12 more
ECOG-ACRIN Cancer Research Group
Testing effectiveness (Phase 2)Looking for participantsNCT07780838
What this trial is testing

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

Who this might be right for
Locally Advanced Ampulla of Vater CarcinomaLocally Advanced Biliary Tract CarcinomaLocally Advanced Extrahepatic Cholangiocarcinoma+20 more
Ohio State University Comprehensive Cancer Center 29
Early research (Phase 1)WithdrawnNCT03117855
What this trial is testing

Capecitabine and Y-90 Radioembolization in Treating Patients With Advanced Bile Duct Cancer in the Liver That Cannot Be Removed by Surgery

Who this might be right for
Bile Duct AdenocarcinomaStage III Intrahepatic CholangiocarcinomaStage IVA Intrahepatic Cholangiocarcinoma+1 more
City of Hope Medical Center
Large-scale testing (Phase 3)Active Not RecruitingNCT06109779
What this trial is testing

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

Who this might be right for
Biliary Tract Cancer
AstraZeneca 760
Large-scale testing (Phase 3)Ended earlyNCT04163900
What this trial is testing

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
NuCana plc 773
Testing effectiveness (Phase 2)Study completedNCT04072445
What this trial is testing

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Gallbladder CarcinomaRefractory Bile Duct Carcinoma+15 more
Mayo Clinic 28
Testing effectiveness (Phase 2)Study completedNCT02392637
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

Who this might be right for
Stage III Intrahepatic Cholangiocarcinoma AJCC v7Stage IIIA Gallbladder Cancer AJCC v7Stage IIIB Gallbladder Cancer AJCC v7+6 more
M.D. Anderson Cancer Center 62
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