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Results for “Stage III Intrahepatic Cholangiocarcinoma AJCC v7”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06178588
What this trial is testing

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

Who this might be right for
Locally Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRecurrent Cholangiocarcinoma+4 more
University of Kansas Medical Center 15
Testing effectiveness (Phase 2)Study completedNCT03201458
What this trial is testing

Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer

Who this might be right for
Gallbladder CarcinomaMetastatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
National Cancer Institute (NCI) 86
Large-scale testing (Phase 3)Not Yet RecruitingNCT07765433
What this trial is testing

Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer

Who this might be right for
Locally Advanced Biliary Tract AdenocarcinomaLocally Advanced Extrahepatic CholangiocarcinomaLocally Advanced Intrahepatic Cholangiocarcinoma+12 more
ECOG-ACRIN Cancer Research Group
Early research (Phase 1)Active Not RecruitingNCT04708067
What this trial is testing

Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaMetastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+3 more
M.D. Anderson Cancer Center 2
Testing effectiveness (Phase 2)Looking for participantsNCT07780838
What this trial is testing

Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma

Who this might be right for
Locally Advanced Ampulla of Vater CarcinomaLocally Advanced Biliary Tract CarcinomaLocally Advanced Extrahepatic Cholangiocarcinoma+20 more
Ohio State University Comprehensive Cancer Center 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT04175912
What this trial is testing

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Who this might be right for
Metastatic CholangiocarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+12 more
National Cancer Institute (NCI) 40
Large-scale testing (Phase 3)Study completedNCT03768414
What this trial is testing

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Who this might be right for
Stage III Distal Bile Duct Cancer AJCC v8Stage III Gallbladder Cancer AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8+14 more
SWOG Cancer Research Network 452
Early research (Phase 1)WithdrawnNCT03117855
What this trial is testing

Capecitabine and Y-90 Radioembolization in Treating Patients With Advanced Bile Duct Cancer in the Liver That Cannot Be Removed by Surgery

Who this might be right for
Bile Duct AdenocarcinomaStage III Intrahepatic CholangiocarcinomaStage IVA Intrahepatic Cholangiocarcinoma+1 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Ended earlyNCT04251715
What this trial is testing

MFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Who this might be right for
Liver and Intrahepatic Bile Duct CarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8+3 more
OHSU Knight Cancer Institute 5
Testing effectiveness (Phase 2)Study completedNCT03579771
What this trial is testing

Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer

Who this might be right for
Resectable CholangiocarcinomaStage IB Intrahepatic Cholangiocarcinoma AJCC v8Stage II Intrahepatic Cholangiocarcinoma AJCC v8+3 more
Emory University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05564403
What this trial is testing

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Gallbladder CarcinomaAdvanced Intrahepatic Cholangiocarcinoma+14 more
National Cancer Institute (NCI) 66
Early research (Phase 1)Active Not RecruitingNCT03257761
What this trial is testing

Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer

Who this might be right for
Extrahepatic Bile Duct Adenocarcinoma, Biliary TypeGallbladder Adenocarcinoma, Biliary TypeMetastatic Pancreatic Adenocarcinoma+25 more
University of Southern California 55
Large-scale testing (Phase 3)Ended earlyNCT02200042
What this trial is testing

Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer

Who this might be right for
Stage III Intrahepatic CholangiocarcinomaStage IVA Intrahepatic Cholangiocarcinoma
NRG Oncology 1
Testing effectiveness (Phase 2)Looking for participantsNCT03942328
What this trial is testing

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+3 more
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT02520141
What this trial is testing

Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

Who this might be right for
CholangiocarcinomaLiver and Intrahepatic Bile Duct CarcinomaStage III Gallbladder Cancer AJCC v7+9 more
M.D. Anderson Cancer Center 61
Testing effectiveness (Phase 2)Study completedNCT02392637
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

Who this might be right for
Stage III Intrahepatic Cholangiocarcinoma AJCC v7Stage IIIA Gallbladder Cancer AJCC v7Stage IIIB Gallbladder Cancer AJCC v7+6 more
M.D. Anderson Cancer Center 62
Early research (Phase 1)WithdrawnNCT02856568
What this trial is testing

Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma

Who this might be right for
Non-Resectable CholangiocarcinomaRecurrent CholangiocarcinomaStage III Extrahepatic Bile Duct Cancer+10 more
Mayo Clinic
Testing effectiveness (Phase 2)WithdrawnNCT05514912
What this trial is testing

Preoperative Nab-paclitaxel, Cisplatin, and Gemcitabine Chemotherapy With or Without Infigratinib Targeted Therapy for the Treatment of Resectable Intrahepatic Cholangiocarcinoma, The OPTIC Trial

Who this might be right for
Resectable Intrahepatic CholangiocarcinomaStage 0 Intrahepatic Cholangiocarcinoma AJCC v8Stage I Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Emory University
Early research (Phase 1)Study completedNCT01825603
What this trial is testing

ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer

Who this might be right for
Ampulla of Vater AdenocarcinomaGallbladder AdenocarcinomaMetastatic Pancreatic Adenocarcinoma+17 more
University of Nebraska 17
Early research (Phase 1)Looking for participantsNCT06058663
What this trial is testing

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Who this might be right for
Locally Advanced Intrahepatic CholangiocarcinomaOligometastatic Intrahepatic CholangiocarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8+2 more
Mayo Clinic 16
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