Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Stage IV Esophageal Squamous Cell Carcinoma”

141 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 141 results

Testing effectiveness (Phase 2)Ended earlyNCT03320629
What this trial is testing

Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Refractory or Metastatic Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 7
Testing effectiveness (Phase 2)Looking for participantsNCT06769113
What this trial is testing

A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy

Who this might be right for
Esophageal Cancer
Shanghai Henlius Biotech 72
Large-scale testing (Phase 3)Study completedNCT04540211
What this trial is testing

Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma

Who this might be right for
Esophageal Cancer
Hoffmann-La Roche 461
Testing effectiveness (Phase 2)Study completedNCT00002984
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center 26
Not applicableStudy completedNCT03000816
What this trial is testing

SBRT for OligoMetastatic ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma Metastatic
Fudan University 34
Testing effectiveness (Phase 2)Active Not RecruitingNCT01142388
What this trial is testing

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Who this might be right for
Metastatic Esophageal AdenocarcinomaMetastatic Esophageal Squamous Cell CarcinomaMetastatic Gastroesophageal Junction Adenocarcinoma+5 more
National Cancer Institute (NCI) 94
Testing effectiveness (Phase 2)Study completedNCT00045526
What this trial is testing

Erlotinib Hydrochloride in Treating Patients With Advanced Esophageal Cancer or Stomach Cancer

Who this might be right for
Adenocarcinoma of the EsophagusAdenocarcinoma of the Gastroesophageal JunctionRecurrent Esophageal Cancer+3 more
National Cancer Institute (NCI) 48
Large-scale testing (Phase 3)Not Yet RecruitingNCT07251062
What this trial is testing

SYS6010, Enlonstobart, and Chemotherapy for First-Line Treatment of Esophageal Squamous Cell Carcinoma.

Who this might be right for
Esophageal Squamous Cell Carcinoma
CSPC Megalith Biopharmaceutical Co.,Ltd. 737
Testing effectiveness (Phase 2)Study completedNCT04785820
What this trial is testing

Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus

Who this might be right for
Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Hoffmann-La Roche 206
Testing effectiveness (Phase 2)Study completedNCT00268346
What this trial is testing

Gefitinib in Treating Patients With Recurrent or Metastatic Esophageal or Gastroesophageal Junction Cancer

Who this might be right for
Esophageal Cancer
Case Comprehensive Cancer Center 58
Not applicableLooking for participantsNCT04221893
What this trial is testing

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Who this might be right for
Stage IV Esophageal AdenocarcinomaStage IV Esophageal Squamous Cell CarcinomaStage IV Gastric Cancer+41 more
University of California, San Francisco 28
Not applicableStudy completedNCT05142709
What this trial is testing

Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.

Who this might be right for
Metastatic Esophageal Squamous Cell Carcinoma
Fudan University 1,197
Testing effectiveness (Phase 2)UnknownNCT03126708
What this trial is testing

Cetuximab in Combination With Paclitaxel Plus Cisplatin Versus Paclitaxel Plus Cisplatin Alone for the First-line Treatment of Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Cancer, Squamous CellCetuximab EffectChemotherapy Effect
Peking University 150
Large-scale testing (Phase 3)Study completedNCT03748134
What this trial is testing

Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )

Who this might be right for
Esophageal Squamous Cell Carcinoma
Innovent Biologics (Suzhou) Co. Ltd. 746
Not applicableLooking for participantsNCT05760391
What this trial is testing

IO Plus Radiotherapy in Patients With Advanced ESCC.

Who this might be right for
Metastatic Esophageal Squamous Cell Carcinoma
Fudan University 100
Testing effectiveness (Phase 2)Study completedNCT02976896
What this trial is testing

Apatinib for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment

Who this might be right for
Esophageal Squamous Cell Carcinoma
Yuhong Li 43
Not applicableLooking for participantsNCT06504615
What this trial is testing

Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France

Who this might be right for
Gastric AdenocarcinomaGastro-esophageal Junction AdenocarcinomaEsophageal Adenocarcinoma (EAC)+1 more
Bristol-Myers Squibb 500
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Testing effectiveness (Phase 2)Study completedNCT00524121
What this trial is testing

Erlotinib and Radiation Therapy in Treating Older Patients With Stage I, Stage II, Stage III, or Stage IV Esophageal Cancer

Who this might be right for
Esophageal Cancer
Roswell Park Cancer Institute 22
Very early researchStudy completedNCT00757549
What this trial is testing

3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx

Who this might be right for
Head and Neck Cancer
Mayo Clinic 30
Load More Results