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Results for “Stage IV Hepatocellular Carcinoma AJCC V8”

35 trials

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Showing 20 of 35 results

Early research (Phase 1)Active Not RecruitingNCT03655002
What this trial is testing

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Who this might be right for
Recurrent Hepatocellular CarcinomaRefractory Liver CarcinomaStage IV Hepatocellular Carcinoma AJCC v8+2 more
City of Hope Medical Center 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT04175912
What this trial is testing

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Who this might be right for
Metastatic CholangiocarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+12 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Looking for participantsNCT04430452
What this trial is testing

Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+4 more
Mary Feng, MD 21
Testing effectiveness (Phase 2)Study completedNCT03439891
What this trial is testing

Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v7+4 more
Robin Kate Kelley 16
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07042919
What this trial is testing

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaCirrhosisStage III Hepatocellular Carcinoma AJCC v8+1 more
Northwestern University 53
Early research (Phase 1)Temporarily pausedNCT06968195
What this trial is testing

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaRecurrent Hepatocellular Carcinoma+3 more
Roswell Park Cancer Institute 24
Not applicableActive Not RecruitingNCT03896646
What this trial is testing

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 42
Early research (Phase 1)Active Not RecruitingNCT04605731
What this trial is testing

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLocally Advanced Hepatocellular Carcinoma+7 more
City of Hope Medical Center 25
Testing effectiveness (Phase 2)Ended earlyNCT05199285
What this trial is testing

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLocally Advanced Hepatocellular Carcinoma+8 more
Academic and Community Cancer Research United 15
Testing effectiveness (Phase 2)Looking for participantsNCT06811116
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI) 92
Testing effectiveness (Phase 2)Active Not RecruitingNCT04941287
What this trial is testing

Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer

Who this might be right for
Metastatic Distal Bile Duct AdenocarcinomaMetastatic Gallbladder CarcinomaMetastatic Intrahepatic Cholangiocarcinoma+7 more
National Cancer Institute (NCI) 57
Not applicableLooking for participantsNCT04221893
What this trial is testing

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Who this might be right for
Stage IV Esophageal AdenocarcinomaStage IV Esophageal Squamous Cell CarcinomaStage IV Gastric Cancer+41 more
University of California, San Francisco 28
Not applicableLooking for participantsNCT06349642
What this trial is testing

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

Who this might be right for
Early Stage Triple-Negative Breast CarcinomaMetastatic Bladder Urothelial CarcinomaMetastatic Cervical Carcinoma+24 more
Mayo Clinic 324
Testing effectiveness (Phase 2)Ended earlyNCT03695250
What this trial is testing

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Who this might be right for
Metastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+5 more
Edward Kim 8
Testing effectiveness (Phase 2)Looking for participantsNCT04380545
What this trial is testing

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 15
Early research (Phase 1)Looking for participantsNCT05791448
What this trial is testing

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Who this might be right for
Advanced CholangiocarcinomaAdvanced Hepatocellular CarcinomaAdvanced Malignant Solid Neoplasm+4 more
University of Southern California 36
Testing effectiveness (Phase 2)Looking for participantsNCT05103904
What this trial is testing

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

Who this might be right for
Recurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC V8Stage IIIA Hepatocellular Carcinoma AJCC V8+5 more
Emory University 19
Early research (Phase 1)Active Not RecruitingNCT04514484
What this trial is testing

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Who this might be right for
Advanced Differentiated Thyroid Gland CarcinomaAdvanced Head and Neck CarcinomaAdvanced Hepatocellular Carcinoma+60 more
National Cancer Institute (NCI) 8
Testing effectiveness (Phase 2)Looking for participantsNCT05168163
What this trial is testing

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Who this might be right for
Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+6 more
Academic and Community Cancer Research United 122
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