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Results for “Stage IV Hepatocellular Carcinoma AJCC v7”

37 trials

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Showing 20 of 37 results

Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Ended earlyNCT05103904
What this trial is testing

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

Who this might be right for
Recurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+5 more
Emory University 3
Early research (Phase 1)Study completedNCT02143401
What this trial is testing

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
CirrhosisHepatitis B InfectionHepatitis C Infection+6 more
National Cancer Institute (NCI) 29
Post-approval studies (Phase 4)Looking for participantsNCT07405086
What this trial is testing

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Hepatocellular Carcinoma+18 more
OHSU Knight Cancer Institute 160
Testing effectiveness (Phase 2)Study completedNCT02940496
What this trial is testing

Pembrolizumab (MK-3475) in Hepatocellular Carcinoma

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaHepatitis C Infection+8 more
M.D. Anderson Cancer Center 15
Not applicableActive Not RecruitingNCT05038254
What this trial is testing

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

Who this might be right for
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+42 more
M.D. Anderson Cancer Center 750
Testing effectiveness (Phase 2)Looking for participantsNCT06811116
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI) 92
Testing effectiveness (Phase 2)Ended earlyNCT03695250
What this trial is testing

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Who this might be right for
Metastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+5 more
Edward Kim 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511504
What this trial is testing

Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma

Who this might be right for
Locally Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+1 more
OHSU Knight Cancer Institute 40
Early research (Phase 1)Active Not RecruitingNCT04514484
What this trial is testing

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Who this might be right for
Advanced Differentiated Thyroid Gland CarcinomaAdvanced Head and Neck CarcinomaAdvanced Hepatocellular Carcinoma+60 more
National Cancer Institute (NCI) 8
Testing effectiveness (Phase 2)Looking for participantsNCT07042919
What this trial is testing

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaCirrhosisStage III Hepatocellular Carcinoma AJCC v8+1 more
Devalingam Mahalingam 59
Testing effectiveness (Phase 2)Study completedNCT01900002
What this trial is testing

Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Who this might be right for
Advanced Adult Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaRecurrent Adult Hepatocellular Carcinoma+8 more
M.D. Anderson Cancer Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04175912
What this trial is testing

Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver

Who this might be right for
Metastatic CholangiocarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+12 more
National Cancer Institute (NCI) 40
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT05168163
What this trial is testing

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Who this might be right for
Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+6 more
Academic and Community Cancer Research United 122
Testing effectiveness (Phase 2)Looking for participantsNCT04380545
What this trial is testing

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 15
Early research (Phase 1)Temporarily pausedNCT05791448
What this trial is testing

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Who this might be right for
Advanced CholangiocarcinomaAdvanced Hepatocellular CarcinomaAdvanced Malignant Solid Neoplasm+4 more
University of Southern California 36
Early research (Phase 1)Active Not RecruitingNCT04605731
What this trial is testing

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLocally Advanced Hepatocellular Carcinoma+7 more
City of Hope Medical Center 25
Testing effectiveness (Phase 2)Looking for participantsNCT04430452
What this trial is testing

Durvalumab With/Without Tremelimumab After Palliative Hypofractionated Radiotherapy for Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+4 more
Mary Feng, MD 21
Large-scale testing (Phase 3)Study completedNCT01015833
What this trial is testing

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Advanced Adult Hepatocellular CarcinomaRecurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v7+7 more
National Cancer Institute (NCI) 356
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