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Results for “Stage IV Hepatocellular Carcinoma AJCC v8”

34 trials

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Showing 20 of 34 results

Large-scale testing (Phase 3)Looking for participantsNCT07166406
What this trial is testing

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8
NRG Oncology 252
Early research (Phase 1)Temporarily pausedNCT06968195
What this trial is testing

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaRecurrent Hepatocellular Carcinoma+3 more
Roswell Park Cancer Institute 24
Not applicableActive Not RecruitingNCT03896646
What this trial is testing

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07405086
What this trial is testing

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Hepatocellular Carcinoma+18 more
OHSU Knight Cancer Institute 160
Early research (Phase 1)Active Not RecruitingNCT04514484
What this trial is testing

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Who this might be right for
Advanced Differentiated Thyroid Gland CarcinomaAdvanced Head and Neck CarcinomaAdvanced Hepatocellular Carcinoma+60 more
National Cancer Institute (NCI) 8
Not applicableLooking for participantsNCT04221893
What this trial is testing

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Who this might be right for
Stage IV Esophageal AdenocarcinomaStage IV Esophageal Squamous Cell CarcinomaStage IV Gastric Cancer+41 more
University of California, San Francisco 28
Not applicableLooking for participantsNCT03823144
What this trial is testing

Intravital Microscopy in Human Solid Tumors

Who this might be right for
Solid Tumor, AdultClinical Stage IV Gastric Cancer AJCC v8Malignant Solid Neoplasm+20 more
Mayo Clinic 85
Testing effectiveness (Phase 2)Study completedNCT05176223
What this trial is testing

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+1 more
Mayo Clinic 29
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+127 more
Mayo Clinic 36
Not applicableActive Not RecruitingNCT05038254
What this trial is testing

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

Who this might be right for
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+42 more
M.D. Anderson Cancer Center 750
Testing effectiveness (Phase 2)Ended earlyNCT05199285
What this trial is testing

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLocally Advanced Hepatocellular Carcinoma+8 more
Academic and Community Cancer Research United 15
Not applicableStudy completedNCT01176604
What this trial is testing

Yttrium Y 90 Glass Microspheres in Treating Patients With Unresectable Hepatocellular Carcinoma

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 299
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Looking for participantsNCT05103904
What this trial is testing

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

Who this might be right for
Recurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC V8Stage IIIA Hepatocellular Carcinoma AJCC V8+5 more
Emory University 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT04251715
What this trial is testing

MFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

Who this might be right for
Liver and Intrahepatic Bile Duct CarcinomaStage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8+3 more
OHSU Knight Cancer Institute 5
Testing effectiveness (Phase 2)Ended earlyNCT03695250
What this trial is testing

BMS-986205 and Nivolumab as First or Second Line Therapy in Treating Patients With Liver Cancer

Who this might be right for
Metastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8+5 more
Edward Kim 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT04941287
What this trial is testing

Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer

Who this might be right for
Metastatic Distal Bile Duct AdenocarcinomaMetastatic Gallbladder CarcinomaMetastatic Intrahepatic Cholangiocarcinoma+7 more
National Cancer Institute (NCI) 57
Testing effectiveness (Phase 2)Looking for participantsNCT06811116
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI) 92
Early research (Phase 1)Active Not RecruitingNCT04605731
What this trial is testing

Durvalumab and Tremelimumab After Radioembolization for the Treatment of Unresectable, Locally Advanced Liver Cancer

Who this might be right for
BCLC Stage B Hepatocellular CarcinomaBCLC Stage C Hepatocellular CarcinomaLocally Advanced Hepatocellular Carcinoma+7 more
City of Hope Medical Center 25
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