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Results for “Stage IV Lip and Oral Cavity Cancer AJCC v8”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)UnknownNCT00003327
What this trial is testing

Paclitaxel in Treating Patients With Recurrent or Refractory Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
Theradex 60
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Active Not RecruitingNCT05721755
What this trial is testing

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+8 more
ECOG-ACRIN Cancer Research Group
Testing effectiveness (Phase 2)Active Not RecruitingNCT05172258
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Who this might be right for
Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+12 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT06868433
What this trial is testing

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
Emory University
Testing effectiveness (Phase 2)WithdrawnNCT06084845
What this trial is testing

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell Carcinoma+12 more
ECOG-ACRIN Cancer Research Group
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552
What this trial is testing

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00036790
What this trial is testing

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersColorectal Cancer+9 more
University of Wisconsin, Madison
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Looking for participantsNCT06997068
What this trial is testing

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

Who this might be right for
Metastatic Oral Cavity CarcinomaRecurrent Oral Cavity CarcinomaStage IVC Lip and Oral Cavity Cancer AJCC v8+15 more
Mayo Clinic 25
Testing effectiveness (Phase 2)Ended earlyNCT00003777
What this trial is testing

Surgery, Radiation Therapy, and Combination Chemotherapy in Treating Patients With Recurrent Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
Abramson Cancer Center at Penn Medicine 35
Early research (Phase 1)UnknownNCT00004097
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced and/or Recurrent Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Looking for participantsNCT06589804
What this trial is testing

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell CarcinomaMetastatic Laryngeal Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI) 158
Testing effectiveness (Phase 2)Active Not RecruitingNCT04862650
What this trial is testing

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+22 more
Marcelo Bonomi
Large-scale testing (Phase 3)Study completedNCT00008398
What this trial is testing

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Who this might be right for
Head and Neck CancerOral ComplicationsRadiation Toxicity
Radiation Therapy Oncology Group
Testing effectiveness (Phase 2)Looking for participantsNCT06980038
What this trial is testing

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell Carcinoma+19 more
National Cancer Institute (NCI) 44
Not applicableLooking for participantsNCT06662058
What this trial is testing

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Cutaneous Squamous Cell Carcinoma of the Head and NeckHead and Neck Carcinoma of Unknown Primary+30 more
Emory University 118
Early research (Phase 1)Looking for participantsNCT07156227
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Hypopharyngeal Squamous Cell Carcinoma+27 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)UnknownNCT00003251
What this trial is testing

Amifostine Plus Chemotherapy and Radiation Therapy in Treating Patients With Advanced, Unresectable Head and Neck Cancer

Who this might be right for
Drug/Agent Toxicity by Tissue/OrganHead and Neck CancerRadiation Toxicity
University of Illinois at Chicago 46
Not applicableWithdrawnNCT05512767
What this trial is testing

A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation

Who this might be right for
Clinical Stage II HPV-Mediated (p16-pos) Oropharyngeal CarcinomaClinical Stage III HPV-Mediated (p16-pos) Oropharyngeal CarcinomaClinical Stage IV HPV-Mediated (p16-pos)Oropharyngeal Carcinoma+13 more
Mayo Clinic
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