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Results for “Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8”

160 trials

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Showing 20 of 160 results

Large-scale testing (Phase 3)Looking for participantsNCT06096844
What this trial is testing

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Who this might be right for
Advanced Lung Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IIIC Lung Cancer AJCC v8+1 more
National Cancer Institute (NCI) 304
Testing effectiveness (Phase 2)Active Not RecruitingNCT03225664
What this trial is testing

Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+7 more
M.D. Anderson Cancer Center 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT04625647
What this trial is testing

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Who this might be right for
Lung AdenocarcinomaLung Non-Small Cell CarcinomaRecurrent Lung Non-Squamous Non-Small Cell Carcinoma+3 more
SWOG Cancer Research Network 116
Not applicableLooking for participantsNCT04151940
What this trial is testing

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8
University of Washington 80
Not applicableEnded earlyNCT05407038
What this trial is testing

Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue

Who this might be right for
Advanced Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8Stage IIIA Lung Cancer AJCC v8+5 more
Mayo Clinic 7
Not applicableStudy completedNCT04229381
What this trial is testing

Resiliency Among Older Adults Receiving Lung Cancer Treatment

Who this might be right for
Advanced Lung CarcinomaExtensive Stage Lung Small Cell CarcinomaStage IIIA Lung Cancer AJCC v8+6 more
Ohio State University Comprehensive Cancer Center 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03600701
What this trial is testing

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaRefractory Lung Non-Small Cell Carcinoma+1 more
National Cancer Institute (NCI) 51
Large-scale testing (Phase 3)Active Not RecruitingNCT03793179
What this trial is testing

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Who this might be right for
Lung Non-Squamous Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IIIC Lung Cancer AJCC v8+1 more
National Cancer Institute (NCI) 600
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Not applicableWithdrawnNCT05412875
What this trial is testing

Pilot Trial of E Cigarettes in Pts Diagnosed With Cancer of the Head, Neck, and Lung

Who this might be right for
Head and Neck Squamous Cell CarcinomaLung Non-Small Cell CarcinomaStage I Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8+15 more
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Large-scale testing (Phase 3)Looking for participantsNCT04181060
What this trial is testing

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Who this might be right for
Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaRecurrent Lung Non-Squamous Non-Small Cell Carcinoma+2 more
National Cancer Institute (NCI) 300
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT05017025
What this trial is testing

Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer

Who this might be right for
Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+6 more
M.D. Anderson Cancer Center 32
Early research (Phase 1)Looking for participantsNCT05098210
What this trial is testing

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more
Fred Hutchinson Cancer Center 25
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT07288034
What this trial is testing

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Who this might be right for
Lung Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IV Lung Cancer AJCC v8
City of Hope Medical Center 535
Not applicableActive Not RecruitingNCT04946279
What this trial is testing

Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer

Who this might be right for
Lung Non-Small Cell CarcinomaStage I Lung Cancer AJCC v8Stage II Lung Cancer AJCC v8+2 more
OHSU Knight Cancer Institute 98
Early research (Phase 1)Active Not RecruitingNCT02595931
What this trial is testing

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Lung Small Cell CarcinomaMetastatic Malignant Solid Neoplasm+15 more
National Cancer Institute (NCI) 66
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