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Results for “Stage IV Squamous Cell Lung Carcinoma AJCC v7”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Ended earlyNCT02452463
What this trial is testing

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

Who this might be right for
Lung Non-Squamous Non-Small Cell CarcinomaRadiation-Induced PneumonitisStage II Lung Non-Small Cell Cancer AJCC v7+6 more
Roswell Park Cancer Institute 8
Early research (Phase 1)Study completedNCT03299088
What this trial is testing

Pembrolizumab and Trametinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer and KRAS Gene Mutations

Who this might be right for
KRAS Gene MutationMetastatic Non-Squamous Non-Small Cell Lung CarcinomaRecurrent Non-Squamous Non-Small Cell Lung Carcinoma+1 more
Jonathan Riess 15
Testing effectiveness (Phase 2)Study completedNCT02417701
What this trial is testing

Sapanisertib in Treating Patients With Stage IV or Recurrent Lung Cancer

Who this might be right for
Recurrent Lung Squamous Cell CarcinomaStage IV Lung Squamous Cell Carcinoma AJCC v7
National Cancer Institute (NCI) 34
Large-scale testing (Phase 3)Ended earlyNCT02926638
What this trial is testing

Lung-MAP: Rilotumumab and Erlotinib Hydrochloride or Erlotinib Hydrochloride Alone as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches

Who this might be right for
MET PositiveRecurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 9
Large-scale testing (Phase 3)Study completedNCT02785939
What this trial is testing

Lung-MAP: Palbociclib as Second-Line Therapy in Treating Cell Cycle Gene Alteration Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
CCND1 Gene AmplificationCCND2 Gene AmplificationCCND3 Gene Amplification+3 more
SWOG Cancer Research Network 53
Testing effectiveness (Phase 2)Study completedNCT03574753
What this trial is testing

Lung-MAP S1400K: c-MET Positive

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC V7
SWOG Cancer Research Network 28
Early research (Phase 1)Study completedNCT03590054
What this trial is testing

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Stage III Cutaneous MelanomaStage IV Cutaneous MelanomaLocally Advanced Melanoma+18 more
Rahul Aggarwal 35
Early research (Phase 1)Study completedNCT02520778
What this trial is testing

Osimertinib and Navitoclax in Treating Patients With EGFR-Positive Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Advanced Lung Non-Squamous Non-Small Cell CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Non-Small Cell Cancer AJCC v7+3 more
National Cancer Institute (NCI) 27
Large-scale testing (Phase 3)Study completedNCT02965378
What this trial is testing

Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
FGFR1 Gene AmplificationFGFR1 Gene MutationFGFR2 Gene Amplification+5 more
SWOG Cancer Research Network 43
Early research (Phase 1)Study completedNCT01727076
What this trial is testing

Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck CarcinomaRecurrent Non-Small Cell Lung Carcinoma+11 more
National Cancer Institute (NCI) 20
Large-scale testing (Phase 3)Study completedNCT02766335
What this trial is testing

Lung-MAP: Durvalumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 116
Testing effectiveness (Phase 2)Study completedNCT03377556
What this trial is testing

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
ATM Gene MutationATR Gene MutationBARD1 Gene Mutation+18 more
SWOG Cancer Research Network 51
Large-scale testing (Phase 3)Active Not RecruitingNCT02785952
What this trial is testing

Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 275
Testing effectiveness (Phase 2)Study completedNCT01532089
What this trial is testing

Erlotinib Hydrochloride With or Without Bevacizumab in Treating Patients With Stage IV Non-small Cell Lung Cancer With Epidermal Growth Factor Receptor Mutations

Who this might be right for
EGFR Exon 19 Deletion MutationEGFR NP_005219.2:p.L858RLung Non-Squamous Non-Small Cell Carcinoma+1 more
Academic and Community Cancer Research United 88
Early research (Phase 1)Study completedNCT02535325
What this trial is testing

Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer

Who this might be right for
Locally Advanced Lung Non-Squamous Non-Small Cell CarcinomaStage III Lung Adenocarcinoma AJCC v7Stage III Lung Large Cell Carcinoma AJCC v7+10 more
National Cancer Institute (NCI) 17
Testing effectiveness (Phase 2)Ended earlyNCT04925986
What this trial is testing

Sitravatinib Plus Pembrolizumab in Patients With Advanced Treatment-Naïve PD-L1+ Non-Squamous NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungLung DiseasesLung Neoplasms+6 more
Sarah Goldberg 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT03074513
What this trial is testing

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Who this might be right for
Appendix AdenocarcinomaHuman Papillomavirus-Related Anal Squamous Cell CarcinomaHuman Papillomavirus-Related Cervical Squamous Cell Carcinoma+18 more
M.D. Anderson Cancer Center 133
Not applicableStudy completedNCT02154490
What this trial is testing

Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 1,864
Testing effectiveness (Phase 2)Study completedNCT03373760
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer

Who this might be right for
Recurrent Squamous Cell Lung CarcinomaStage IV Squamous Cell Lung Carcinoma AJCC v7
SWOG Cancer Research Network 67
Early research (Phase 1)Study completedNCT03229278
What this trial is testing

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmMetastatic Melanoma+26 more
Rutgers, The State University of New Jersey 14
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