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Results for “Stage IVA Adenocarcinoma of the Gastroesophageal Junction”

20 trials

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Showing 20 of 20 results

Testing effectiveness (Phase 2)Study completedNCT03918499
What this trial is testing

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage IV Gastric Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastric Cancer AJCC v8+15 more
City of Hope Medical Center 9
Early research (Phase 1)Active Not RecruitingNCT04220827
What this trial is testing

Paclitaxel for the Treatment of Gastric or Gastroesophageal Cancer

Who this might be right for
Clinical Stage IV Gastric Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastric Cancer AJCC v8+14 more
M.D. Anderson Cancer Center 27
Not applicableLooking for participantsNCT04221893
What this trial is testing

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

Who this might be right for
Stage IV Esophageal AdenocarcinomaStage IV Esophageal Squamous Cell CarcinomaStage IV Gastric Cancer+41 more
University of California, San Francisco 28
Large-scale testing (Phase 3)Looking for participantsNCT03801876
What this trial is testing

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Who this might be right for
Clinical Stage I Esophageal Adenocarcinoma AJCC v8Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8+10 more
NRG Oncology 300
Early research (Phase 1)Looking for participantsNCT04511039
What this trial is testing

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Gastroesophageal Junction AdenocarcinomaClinical Stage IV Gastroesophageal Junction Adenocarcinoma+26 more
Roswell Park Cancer Institute 45
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+127 more
Mayo Clinic 36
Very early researchStudy completedNCT03395847
What this trial is testing

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+22 more
M.D. Anderson Cancer Center 9
Large-scale testing (Phase 3)Temporarily pausedNCT03604991
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8+5 more
National Cancer Institute (NCI) 278
Early research (Phase 1)Active Not RecruitingNCT04460937
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Who this might be right for
Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+56 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT04097028
What this trial is testing

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8+13 more
Roswell Park Cancer Institute 22
Testing effectiveness (Phase 2)Looking for participantsNCT04660760
What this trial is testing

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+28 more
Academic and Community Cancer Research United
Testing effectiveness (Phase 2)Looking for participantsNCT04771520
What this trial is testing

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT03337087
What this trial is testing

Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CarcinomaMetastatic Colorectal CarcinomaMetastatic Gastroesophageal Junction Adenocarcinoma+6 more
Academic and Community Cancer Research United 18
Early research (Phase 1)WithdrawnNCT05296005
What this trial is testing

Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage II Gastric Cancer AJCC v8Clinical Stage IIA Gastric Cancer AJCC v8+22 more
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT05836584
What this trial is testing

Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Gastric Cancer AJCC v8+7 more
National Cancer Institute (NCI) 240
Testing effectiveness (Phase 2)Active Not RecruitingNCT03776487
What this trial is testing

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Who this might be right for
Clinical Stage 0 Gastric Cancer AJCC v8Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage I Gastric Cancer AJCC v8+25 more
M.D. Anderson Cancer Center 32
Not applicableStudy completedNCT03707574
What this trial is testing

Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study

Who this might be right for
Advanced Malignant NeoplasmAdvanced MelanomaAdvanced Renal Cell Carcinoma+51 more
National Cancer Institute (NCI) 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT04929392
What this trial is testing

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8+16 more
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT04522336
What this trial is testing

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Who this might be right for
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+16 more
M.D. Anderson Cancer Center
Very early researchLooking for participantsNCT05041153
What this trial is testing

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastric AdenocarcinomaAdvanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Gastric Cancer AJCC v8+30 more
M.D. Anderson Cancer Center 15
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