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Results for “Stage IVA Pharyngeal Cancer”

44 trials

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Showing 20 of 44 results

Large-scale testing (Phase 3)Ended earlyNCT04458909
What this trial is testing

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

Who this might be right for
Metastatic Nasopharyngeal CarcinomaMetastatic Nasopharyngeal Keratinizing Squamous Cell CarcinomaMetastatic Nasopharyngeal Nonkeratinizing Carcinoma+8 more
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)Study completedNCT02159703
What this trial is testing

A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Cancer
Abramson Cancer Center at Penn Medicine 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Not applicableLooking for participantsNCT01365169
What this trial is testing

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Who this might be right for
Malignant Head and Neck NeoplasmMalignant NeoplasmMetastatic Malignant Neoplasm in the Neck+45 more
M.D. Anderson Cancer Center 590
Early research (Phase 1)Ended earlyNCT00004261
What this trial is testing

EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or High Grade Soft Tissue Sarcoma

Who this might be right for
Breast CancerCervical CancerHead and Neck Cancer+2 more
University Health Network, Toronto
Testing effectiveness (Phase 2)WithdrawnNCT04231864
What this trial is testing

Durvalumab and Epacadostat for Treatment of Unresectable, Recurrent, or Metastatic Epstein-Barr Virus Positive Nasopharyngeal Cancer

Who this might be right for
Epstein-Barr Virus PositiveMetastatic Nasopharyngeal CarcinomaRecurrent Nasopharyngeal Carcinoma+4 more
Alain Algazi
Large-scale testing (Phase 3)Not Yet RecruitingNCT06095167
What this trial is testing

Induction Chemotherapy and Immunotherapy Combined Radiotherapy With or Without Concurrent Chemotherapy for Stage III-IVa NPC

Who this might be right for
Nasopharyngeal Carcinoma
Fujian Cancer Hospital 476
Testing effectiveness (Phase 2)Looking for participantsNCT02734537
What this trial is testing

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Who this might be right for
Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell Carcinoma+13 more
ECOG-ACRIN Cancer Research Group 189
Large-scale testing (Phase 3)Study completedNCT02940925
What this trial is testing

TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Sun Yat-sen University 241
Testing effectiveness (Phase 2)Study completedNCT03422536
What this trial is testing

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Basaloid CarcinomaRecurrent Head and Neck Squamous Cell CarcinomaRecurrent Oropharyngeal Squamous Cell Carcinoma+21 more
University of Arizona 78
Testing effectiveness (Phase 2)Active Not RecruitingNCT03074513
What this trial is testing

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Who this might be right for
Appendix AdenocarcinomaHuman Papillomavirus-Related Anal Squamous Cell CarcinomaHuman Papillomavirus-Related Cervical Squamous Cell Carcinoma+18 more
M.D. Anderson Cancer Center 133
Testing effectiveness (Phase 2)Active Not RecruitingNCT04862650
What this trial is testing

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+22 more
Marcelo Bonomi
Testing effectiveness (Phase 2)Study completedNCT01806675
What this trial is testing

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Who this might be right for
Adult Giant Cell GlioblastomaAdult GlioblastomaAdult Gliosarcoma+41 more
Sanjiv Sam Gambhir 25
Early research (Phase 1)Active Not RecruitingNCT01552434
What this trial is testing

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Who this might be right for
Advanced Malignant NeoplasmCastleman DiseaseDigestive System Carcinoma+36 more
M.D. Anderson Cancer Center 155
Early research (Phase 1)Looking for participantsNCT06611150
What this trial is testing

Concurrent Nab-paclitaxel with Intensity-modulated Radiation Therapy in Patients with Stage III-IVa Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma (NPC)
Sun Yat-sen University 24
Large-scale testing (Phase 3)Study completedNCT03258554
What this trial is testing

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI) 196
Not applicableWithdrawnNCT04140513
What this trial is testing

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Oropharyngeal Squamous Cell Carcinoma+5 more
Ohio State University Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02339558
What this trial is testing

Nivolumab in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Cancer

Who this might be right for
Nasopharyngeal Nonkeratinizing CarcinomaRecurrent Nasopharynx CarcinomaStage III Nasopharyngeal Carcinoma AJCC v7+4 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02538510
What this trial is testing

Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery

Who this might be right for
Head and Neck Squamous Cell CarcinomaRecurrent Nasal Cavity and Paranasal Sinus Squamous Cell CarcinomaRecurrent Nasopharynx Carcinoma+12 more
University of Washington 50
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