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Results for “Stage IVB Lung Cancer AJCC v8”

88 trials

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Showing 20 of 88 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04625647
What this trial is testing

Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Who this might be right for
Lung AdenocarcinomaLung Non-Small Cell CarcinomaRecurrent Lung Non-Squamous Non-Small Cell Carcinoma+3 more
SWOG Cancer Research Network 116
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)WithdrawnNCT05161533
What this trial is testing

Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial

Who this might be right for
Extensive Stage Lung Small Cell CarcinomaStage IV Lung Cancer AJCC v8Stage IVA Lung Cancer AJCC v8+1 more
University of Washington
Testing effectiveness (Phase 2)Active Not RecruitingNCT04516070
What this trial is testing

Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis

Who this might be right for
Metastatic Lung Small Cell CarcinomaMetastatic Malignant Neoplasm in the BrainStage IV Lung Cancer AJCC v8+2 more
M.D. Anderson Cancer Center 55
Early research (Phase 1)WithdrawnNCT06982222
What this trial is testing

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+4 more
National Cancer Institute (NCI)
Not applicableActive Not RecruitingNCT05215769
What this trial is testing

A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Carcinoma+5 more
Ohio State University Comprehensive Cancer Center 243
Early research (Phase 1)Looking for participantsNCT05234307
What this trial is testing

PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8+2 more
Dwight Owen 30
Early research (Phase 1)Active Not RecruitingNCT04250545
What this trial is testing

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

Who this might be right for
Leptomeningeal NeoplasmMetastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the Brain+4 more
National Cancer Institute (NCI) 22
Very early researchLooking for participantsNCT05493566
What this trial is testing

Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer

Who this might be right for
Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8Stage IVA Lung Cancer AJCC v8+1 more
Emory University 15
Not applicableStudy completedNCT05213078
What this trial is testing

Family Caregivers in Underserved Populations Providing Complex Cancer Care

Who this might be right for
Malignant Female Reproductive System NeoplasmStage 0 Lung Cancer AJCC v8Stage I Lung Cancer AJCC v8+14 more
City of Hope Medical Center 48
Not applicableStudy completedNCT04229381
What this trial is testing

Resiliency Among Older Adults Receiving Lung Cancer Treatment

Who this might be right for
Advanced Lung CarcinomaExtensive Stage Lung Small Cell CarcinomaStage IIIA Lung Cancer AJCC v8+6 more
Ohio State University Comprehensive Cancer Center 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03965689
What this trial is testing

Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

Who this might be right for
Metastatic Lung Non-Small Cell Squamous CarcinomaMetastatic Lung Non-Squamous Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8+5 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT04662645
What this trial is testing

Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers

Who this might be right for
CaregiverMalignant Pleural NeoplasmMetastatic Thymic Carcinoma+9 more
Ohio State University Comprehensive Cancer Center 68
Not applicableStudy completedNCT05342571
What this trial is testing

A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer

Who this might be right for
Advanced Lung CarcinomaMetastatic Lung CarcinomaStage IV Lung Cancer AJCC v8+2 more
Ohio State University Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04285671
What this trial is testing

Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRefractory Lung Non-Small Cell CarcinomaStage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8+2 more
Jonsson Comprehensive Cancer Center
Not applicableStudy completedNCT00862680
What this trial is testing

4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis

Who this might be right for
Metastatic Malignant Neoplasm in the LiverMetastatic Malignant Neoplasm in the LungStage IV Colorectal Cancer AJCC v8+6 more
M.D. Anderson Cancer Center 75
Testing effectiveness (Phase 2)Study completedNCT03749460
What this trial is testing

Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

Who this might be right for
Metastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the LungSalivary Gland Carcinoma+4 more
University of Washington 20
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Study completedNCT03845296
What this trial is testing

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationLoss of Heterozygosity+8 more
SWOG Cancer Research Network 64
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