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Results for “Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST)”

3 trials

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Showing 3 of 3 results

Testing effectiveness (Phase 2)Study completedNCT03556384
What this trial is testing

Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

Who this might be right for
Gastrointestinal Stromal TumorsSdhGIST+1 more
Adam Burgoyne, MD, PhD 23
Testing effectiveness (Phase 2)Ended earlyNCT03165721
What this trial is testing

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Who this might be right for
ParagangliomaGastrointestinal Stromal TumorsCarcinoma, Renal Cell+2 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT02071862
What this trial is testing

Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

Who this might be right for
Solid TumorsTriple-Negative Breast CancerNon Small Cell Lung Cancer+7 more
Calithera Biosciences, Inc 210