Post-approval studies (Phase 4)Study completedNCT02729714What this trial is testingA Pilot Study of Suvorexant for Insomnia in Parkinson DiseaseWho this might be right forInsomnia Burdick, Daniel, M.D. 21
Post-approval studies (Phase 4)Study completedNCT04092894What this trial is testingSuvorexant and Sleep/Delirium in ICU PatientsWho this might be right forInsomniaSleep FragmentationSleep Initiation and Maintenance Disorders+1 more Beth Israel Deaconess Medical Center 100
Very early researchStudy completedNCT03937986What this trial is testingSuvorexant and CocaineWho this might be right forCocaine Use Disorder William Stoops 8
Early research (Phase 1)Study completedNCT05106153What this trial is testingDetermine the Abuse Potential of Seltorexant Compared to Suvorexant and ZolpidemWho this might be right forHealthy Non-dependent, Recreational Sedative UsersAbuse Potential Janssen Research & Development, LLC 127
Testing effectiveness (Phase 2)Study completedNCT04229095What this trial is testingMedication Development in Alcoholism: Suvorexant Versus PlaceboWho this might be right forAlcohol Use Disorder (AUD) The Scripps Research Institute 26
Testing effectiveness (Phase 2)Study completedNCT05145764What this trial is testingSuvorexant as an Adjunct to Buprenorphine in Persons Who Use FentanylWho this might be right forSuvorexantPlaceboOpioid Use Disorder Johns Hopkins University 76
Post-approval studies (Phase 4)Study completedNCT05823844What this trial is testingEfficacy of Suvorexant on Post-operative Sleep DisturbanceWho this might be right forPostoperative InsomniaPostoperative Delirium Columbia University 100
Testing effectiveness (Phase 2)Ended earlyNCT03897062What this trial is testingSuvorexant in the Management Comorbid Sleep Disorder and Alcohol DependenceWho this might be right forInsomniaAlcohol Use Disorder The Florey Institute of Neuroscience and Mental Health 22
Post-approval studies (Phase 4)Study completedNCT02704754What this trial is testingSuvorexant and Trauma Related InsomniaWho this might be right forInsomniaPosttraumatic Stress Disorder Howard University 41
Testing effectiveness (Phase 2)Looking for participantsNCT06854224What this trial is testingOrexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical TrialWho this might be right forSuicide RiskMajor Depressive Disorder (MDD) Marianne Goodman 30
Post-approval studies (Phase 4)Study completedNCT03312517What this trial is testingStudy to Compare the Awakening Threshold Effects of Belsomra 10 mg and 20 mg to Placebo in Non-elderly InsomniacsWho this might be right forInsomnia Henry Ford Health System 12
Large-scale testing (Phase 3)Study completedNCT02750306What this trial is testingSafety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061)Who this might be right forSleep Initiation and Maintenance DisordersAlzheimer Disease Merck Sharp & Dohme LLC 285
Testing effectiveness (Phase 2)Study completedNCT05733286What this trial is testingREPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With SuvorexantWho this might be right forDelirium in Old Age Duke University 142
Post-approval studies (Phase 4)Study completedNCT02527564What this trial is testingEfficacy of Suvorexant to Treat Insomnia Related to Bipolar DisorderWho this might be right forInsomniaBipolar Disorder Stanford University 61
Early research (Phase 1)Study completedNCT01059851What this trial is testingPharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)Who this might be right forInsomnia Merck Sharp & Dohme LLC 16
Testing effectiveness (Phase 2)Study completedNCT04234997What this trial is testingSuvorexant to Reduce Symptoms of Nicotine UseWho this might be right forSmoking Cessation The University of Texas Health Science Center, Houston 14
Post-approval studies (Phase 4)Ended earlyNCT02684136What this trial is testingSuvorexant in Insomnia Co-morbid With FibromyalgiaWho this might be right forInsomniaFibromyalgia Henry Ford Health System 10
Testing effectiveness (Phase 2)Ended earlyNCT05711862What this trial is testingThe Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use DisorderWho this might be right forMethamphetamine Use Disorder The University of Texas Health Science Center, Houston 7
Post-approval studies (Phase 4)Study completedNCT04706091What this trial is testingEfficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic InsomniaWho this might be right forRestless Legs SyndromeInsomniaSleep Disorder Massachusetts General Hospital 46
Post-approval studies (Phase 4)Looking for participantsNCT03642028What this trial is testingSuvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic StressWho this might be right forSleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic VA Office of Research and Development 190