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Results for “Symptomatic Hypertrophic Cardiomyopathy (HCM)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06412666
What this trial is testing

Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Who this might be right for
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 65
Testing effectiveness (Phase 2)Looking for participantsNCT07023614
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc. 165
Large-scale testing (Phase 3)Study completedNCT05174416
What this trial is testing

Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
LianBio LLC 81
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Testing effectiveness (Phase 2)Ended earlyNCT05556343
What this trial is testing

Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 18
Large-scale testing (Phase 3)Active Not RecruitingNCT06081894
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 500
Large-scale testing (Phase 3)Enrolling By InvitationNCT04848506
What this trial is testing

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

Who this might be right for
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 900
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Large-scale testing (Phase 3)Active Not RecruitingNCT06481891
What this trial is testing

Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Cardiomyopathy, HypertrophicNon-obstructive Hypertrophic Cardiomyopathy
Lexicon Pharmaceuticals 500
Not applicableStudy completedNCT02994615
What this trial is testing

Evaluating Microvascular Dysfunction in Symptomatic Patients With HypertroPhic CaRdiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 19
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Not applicableUnknownNCT05771987
What this trial is testing

Permanent Pacing for Drug-refractory Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Istituto Auxologico Italiano 10
Testing effectiveness (Phase 2)Study completedNCT00011076
What this trial is testing

Pirfenidone to Treat Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy
National Heart, Lung, and Blood Institute (NHLBI) 50
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 331
Large-scale testing (Phase 3)Study completedNCT04349072
What this trial is testing

Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

Who this might be right for
HOCM, Hypertrophic Obstructive Cardiomyopathy
Bristol-Myers Squibb 112
Not applicableLooking for participantsNCT05489705
What this trial is testing

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 1,700
Large-scale testing (Phase 3)Active Not RecruitingNCT07023341
What this trial is testing

Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bayer 36
Large-scale testing (Phase 3)Study completedNCT05767346
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 175
Not applicableLooking for participantsNCT07150299
What this trial is testing

Myocardial Perfusion Changes Following Optimal Medical Treatment in Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Obstructive Cardiomyopathy \(HOCM\)
Medical University of Vienna 20
Large-scale testing (Phase 3)Ended earlyNCT02291237
What this trial is testing

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy
Gilead Sciences 172
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