Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Symptomatic Obstructive Hypertrophic Cardiomyopathy”

39 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 39 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06081894
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 500
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Not applicableEnded earlyNCT06775886
What this trial is testing

Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic CardiomyopathyHypertrophic Cardiomyopathy
Montefiore Medical Center 1
Not applicableUnknownNCT05771987
What this trial is testing

Permanent Pacing for Drug-refractory Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Istituto Auxologico Italiano 10
Not applicableActive Not RecruitingNCT06947590
What this trial is testing

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
HCM - Hypertrophic CardiomyopathyMavacamten
Xu Liu 78
Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Large-scale testing (Phase 3)Ended earlyNCT02291237
What this trial is testing

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy
Gilead Sciences 172
Early research (Phase 1)Study completedNCT03767855
What this trial is testing

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Who this might be right for
Symptomatic Obstructive Hypertrophic CardiomyopathyHealthy Subjects
Cytokinetics 114
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Large-scale testing (Phase 3)Study completedNCT05174416
What this trial is testing

Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
LianBio LLC 81
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07675668
What this trial is testing

Aom0304 in Adult Patients With Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Obstructive HCM (oHCM)Non-obstructive HCM (nHCM)
Amckaus PTY LTD. 56
Large-scale testing (Phase 3)Study completedNCT05767346
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 175
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Not applicableLooking for participantsNCT07150299
What this trial is testing

Myocardial Perfusion Changes Following Optimal Medical Treatment in Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Obstructive Cardiomyopathy \(HOCM\)
Medical University of Vienna 20
Testing effectiveness (Phase 2)Study completedNCT03442764
What this trial is testing

Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 59
Testing effectiveness (Phase 2)Looking for participantsNCT07023614
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc. 165
Large-scale testing (Phase 3)Enrolling By InvitationNCT04848506
What this trial is testing

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

Who this might be right for
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 900
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Large-scale testing (Phase 3)Ended earlyNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580
Large-scale testing (Phase 3)Active Not RecruitingNCT07023341
What this trial is testing

Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bayer 36
Next Page