Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Symptomatic Obstructive Hypertrophic Cardiomyopathy”

36 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 36 results

Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Post-approval studies (Phase 4)Looking for participantsNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
Large-scale testing (Phase 3)Study completedNCT04349072
What this trial is testing

Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

Who this might be right for
HOCM, Hypertrophic Obstructive Cardiomyopathy
Bristol-Myers Squibb 112
Not applicableUnknownNCT05771987
What this trial is testing

Permanent Pacing for Drug-refractory Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Istituto Auxologico Italiano 10
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Testing effectiveness (Phase 2)Study completedNCT03442764
What this trial is testing

Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 59
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 500
Large-scale testing (Phase 3)Looking for participantsNCT06481891
What this trial is testing

Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Cardiomyopathy, HypertrophicNon-obstructive Hypertrophic Cardiomyopathy
Lexicon Pharmaceuticals 500
Large-scale testing (Phase 3)Active Not RecruitingNCT06081894
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

Who this might be right for
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 500
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Testing effectiveness (Phase 2)Study completedNCT00001960
What this trial is testing

Studying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart Muscle

Who this might be right for
Hypertrophic Cardiomyopathy
National Heart, Lung, and Blood Institute (NHLBI) 50
Testing effectiveness (Phase 2)Study completedNCT03496168
What this trial is testing

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

Who this might be right for
Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 13
Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Large-scale testing (Phase 3)Looking for participantsNCT07023341
What this trial is testing

Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bayer 34
Large-scale testing (Phase 3)Study completedNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Not applicableEnded earlyNCT06775886
What this trial is testing

Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic CardiomyopathyHypertrophic Cardiomyopathy
Montefiore Medical Center 1
Not applicableLooking for participantsNCT07150299
What this trial is testing

Myocardial Perfusion Changes Following Optimal Medical Treatment in Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Obstructive Cardiomyopathy \(HOCM\)
Medical University of Vienna 20
Large-scale testing (Phase 3)Looking for participantsNCT06412666
What this trial is testing

Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Who this might be right for
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 55
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Load More Results