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Results for “Symptomatic Obstructive Hypertrophic Cardiomyopathy”

36 trials

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Showing 20 of 36 results

Not applicableActive Not RecruitingNCT06947590
What this trial is testing

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
HCM - Hypertrophic CardiomyopathyMavacamten
Xu Liu 78
Not applicableUnknownNCT05771987
What this trial is testing

Permanent Pacing for Drug-refractory Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy.

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Istituto Auxologico Italiano 10
Large-scale testing (Phase 3)Study completedNCT05414175
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Bristol-Myers Squibb 38
Large-scale testing (Phase 3)Looking for participantsNCT06481891
What this trial is testing

Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Cardiomyopathy, HypertrophicNon-obstructive Hypertrophic Cardiomyopathy
Lexicon Pharmaceuticals 500
Testing effectiveness (Phase 2)Looking for participantsNCT07023614
What this trial is testing

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc. 165
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Post-approval studies (Phase 4)Active Not RecruitingNCT07004972
What this trial is testing

Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Who this might be right for
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 50
Large-scale testing (Phase 3)Looking for participantsNCT06412666
What this trial is testing

Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Who this might be right for
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 55
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Post-approval studies (Phase 4)Looking for participantsNCT05569382
What this trial is testing

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Non-obstructive Hypertrophic Cardiomyopathy
Morten Steen Kvistholm Jensen 100
Not applicableNot Yet RecruitingNCT06856265
What this trial is testing

Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic CardiomyopathyMavacamtenRadiofrequency Ablation
Shanghai Chest Hospital 40
Large-scale testing (Phase 3)Study completedNCT03470545
What this trial is testing

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
MyoKardia, Inc. 251
Large-scale testing (Phase 3)Active Not RecruitingNCT06081894
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

Who this might be right for
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Cytokinetics 500
Testing effectiveness (Phase 2)Study completedNCT00001960
What this trial is testing

Studying the Effectiveness of Pacemaker Therapy in Children Who Have Thickened Heart Muscle

Who this might be right for
Hypertrophic Cardiomyopathy
National Heart, Lung, and Blood Institute (NHLBI) 50
Large-scale testing (Phase 3)Study completedNCT05174416
What this trial is testing

Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
LianBio LLC 81
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 331
Large-scale testing (Phase 3)Study completedNCT05582395
What this trial is testing

Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 580
Large-scale testing (Phase 3)Study completedNCT05767346
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 175
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