Testing effectiveness (Phase 2)Ended earlyNCT01386372What this trial is testingTolvaptan for In-hospital HyponatremiaWho this might be right forHyponatremia Mario Negri Institute for Pharmacological Research 3
Not applicableWithdrawnNCT01425125What this trial is testingFractional Urate Excretion in Nonedematous HyponatremiaWho this might be right forCerebral HyponatremiaSIADHCerebral Salt-wasting Syndrome+1 more NYU Langone Health
Not applicableStudy completedNCT00390962What this trial is testingThe "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)Who this might be right forStrokeTransient Ischemic Attack University Hospital, Basel, Switzerland 469
Post-approval studies (Phase 4)WithdrawnNCT00298753What this trial is testingUrinary Aquaporine 2 in Patients With Syndrome of Inappropriate ADH-secretion Caused by Treatment With Antiepileptic MedicineWho this might be right forSyndrome of Inappropriate ADH-secretion Regional Hospital Holstebro
Post-approval studies (Phase 4)Study completedNCT04447911What this trial is testingEffects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic HyponatremiaWho this might be right forHyponatremiaSIADHLiver Failure+1 more University Hospital, Basel, Switzerland 113
Not applicableActive Not RecruitingNCT04790175What this trial is testingSamsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADHWho this might be right forAntidiuretic Hormone, Inappropriate Secretion Otsuka Pharmaceutical Co., Ltd. 300
Not applicableStudy completedNCT02548845What this trial is testingAn Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in SpainWho this might be right forHyponatremiaSyndrome of Inappropriate ADH (SIADH) Secretion Otsuka Pharmaceutical Europe Ltd 70
Not applicableUnknownNCT01228682What this trial is testingPost-Authorisation Safety Study of Samsca (Tolvaptan) Used in Routine Medical PracticeWho this might be right forSIADHNon-SIADH HyponatremiaNon-Hyponatremia Otsuka Frankfurt Research Institute GmbH 200
Large-scale testing (Phase 3)Study completedNCT00264927What this trial is testingEfficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone SecretionWho this might be right forInappropriate ADH SyndromeHyponatremia Sanofi 77
Large-scale testing (Phase 3)Study completedNCT02729766What this trial is testingEffects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE StudyWho this might be right forInappropriate ADH Syndrome University Hospital, Basel, Switzerland 15
Large-scale testing (Phase 3)Study completedNCT00264914What this trial is testingSafety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone SecretionWho this might be right forInappropriate ADH SyndromeHyponatremia Sanofi 57
Not applicableStudy completedNCT01056848What this trial is testingInternational, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430Who this might be right forHyponatremia With Normal Extracellular Fluid VolumeHyponatremia With Excess Extracellular Fluid Volume CardioKine Inc. 135
Not applicableStudy completedNCT02573077What this trial is testingAn Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in ItalyWho this might be right forHyponatremiaSyndrome of Inappropriate ADH (SIADH) SecretionCancer Otsuka Pharmaceutical Europe Ltd 69
Large-scale testing (Phase 3)Study completedNCT00072683What this trial is testing"SALT Trial" Study of Ascending Levels of Tolvaptan in HyponatremiaWho this might be right forHyponatremiasWater IntoxicationInappropriate ADH Syndrome+1 more Otsuka Pharmaceutical Development & Commercialization, Inc. 205
Not applicableEnded earlyNCT02545114What this trial is testingTolvaptan for Patients With Acute Neurological InjuriesWho this might be right forHyponatremiaSIADH Polderman, Kees, H., MD, PhD 25
Not applicableStudy completedNCT01465672What this trial is testingCopeptin as a Diagnostic Marker in the Management of Neurosurgical Patients With Disturbance of Water HomeostasisWho this might be right forPituitary Adenoma University Hospital, Basel, Switzerland 125
Large-scale testing (Phase 3)Ended earlyNCT00728091What this trial is testingA Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional HyponatremiaWho this might be right forHyponatremiaInappropriate ADH Syndrome Sanofi 2
Testing effectiveness (Phase 2)Study completedNCT00032734What this trial is testingEfficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone SecretionWho this might be right forSyndrome of Inappropriate ADH (SIADH) SecretionHyponatremia Sanofi 35