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Results for “Systemic Mast Cell Activation”

101 trials

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Showing 20 of 101 results

Testing effectiveness (Phase 2)Study completedNCT00186628
What this trial is testing

Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD

Who this might be right for
Leukemia, Mast-CellMantle-cell Lymphoma
Stanford University 36
Not applicableStudy completedNCT01869777
What this trial is testing

Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia

Who this might be right for
Acute Undifferentiated LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+8 more
Wake Forest University Health Sciences 102
Not applicableStudy completedNCT00001756
What this trial is testing

Study of Mast Cell Precursors

Who this might be right for
MastocytosisHealthy Volunteer
National Institute of Allergy and Infectious Diseases (NIAID) 202
Large-scale testing (Phase 3)UnknownNCT01602939
What this trial is testing

Cladribine Plus Pegylated Interpheron Alfa-2a in Systemic Mastocytosis

Who this might be right for
Systemic Mastocytosis
Hospital Virgen de la Salud 10
Early research (Phase 1)Looking for participantsNCT05362773
What this trial is testing

MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Leukemia, Acute MyeloidMyelodysplastic SyndromesClassical Hodgkin Lymphoma+5 more
MacroGenics 130
Early research (Phase 1)Study completedNCT02571036
What this trial is testing

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Who this might be right for
Gastrointestinal Stromal TumorsAdvanced Systemic MastocytosisAdvanced Cancers
Deciphera Pharmaceuticals, LLC 282
Not applicableActive Not RecruitingNCT01199562
What this trial is testing

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

Who this might be right for
Hematopoietic/Lymphoid CancerAccelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated Leukemia+151 more
City of Hope Medical Center 153
Not applicableAvailableNCT06915766
What this trial is testing

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

Who this might be right for
Systemic Mastocytoses, IndolentSystemic Mastocytoses, Aggressive
Cogent Biosciences, Inc.
Not applicableStudy completedNCT04695431
What this trial is testing

Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM

Who this might be right for
Advanced Systemic MastocytosisAggressive Systemic MastocytosisSystemic Mastocytosis With an Associated Hematological Neoplasm+1 more
Blueprint Medicines Corporation 317
Not applicableStudy completedNCT01053494
What this trial is testing

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+84 more
Wake Forest University Health Sciences 80
Not applicableLooking for participantsNCT07255638
What this trial is testing

A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in Germany

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 80
Not applicableEnded earlyNCT00952185
What this trial is testing

Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+7 more
City of Hope Medical Center 9
Testing effectiveness (Phase 2)UnknownNCT01920204
What this trial is testing

Midostaurin in Indolent Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
University Medical Center Groningen 20
Large-scale testing (Phase 3)Looking for participantsNCT04910685
What this trial is testing

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

Who this might be right for
Indolent Systemic MastocytosisSmoldering Systemic Mastocytosis
Blueprint Medicines Corporation 534
Testing effectiveness (Phase 2)Study completedNCT00171912
What this trial is testing

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Who this might be right for
Hypereosinophilic SyndromeSystemic MastocytosisChronic Myelomonocytic Leukemia+1 more
Novartis Pharmaceuticals 38
Testing effectiveness (Phase 2)Study completedNCT00493129
What this trial is testing

Ontak (Denileukin Diftitox) in Patients With Systemic Mastocytosis (SM)

Who this might be right for
LeukemiaSystemic Mastocytosis
M.D. Anderson Cancer Center 8
Testing effectiveness (Phase 2)Study completedNCT00118352
What this trial is testing

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Who this might be right for
Acute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+61 more
Fred Hutchinson Cancer Center 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03731260
What this trial is testing

(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis

Who this might be right for
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation 251
Not applicableStudy completedNCT00001760
What this trial is testing

Cytokine Production Patterns in Patients With Systemic Mastocytosis Compared With Atopic Dermatitis and Healthy Individuals

Who this might be right for
Atopic DermatitisHealthyMastocytosis
National Institute of Allergy and Infectious Diseases (NIAID) 40
Testing effectiveness (Phase 2)UnknownNCT00979160
What this trial is testing

Evaluation of Response of Dasatinib to Treat Mastocytosis

Who this might be right for
Systemic Mastocytosis
Federico II University 30
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