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Results for “Systemic Mastocytoses”

103 trials

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Showing 20 of 103 results

Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Not applicableEnded earlyNCT00726830
What this trial is testing

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)WithdrawnNCT03739606
What this trial is testing

Flotetuzumab in Treating Patients With Recurrent or Refractory CD123 Positive Blood Cancer

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center
Not applicableStudy completedNCT02620254
What this trial is testing

Mast Cell Connect: A Registry for Patients With Mastocytosis

Who this might be right for
Mastocytosis
Blueprint Medicines Corporation 743
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT00782067
What this trial is testing

Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

Who this might be right for
Leukemia
Novartis Pharmaceuticals 116
Testing effectiveness (Phase 2)Study completedNCT00831974
What this trial is testing

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Who this might be right for
Mastocytosis
AB Science 23
Early research (Phase 1)Study completedNCT02561988
What this trial is testing

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

Who this might be right for
Aggressive Systemic MastocytosisSystemic Mastocytosis-associated Hematologic Non-mast Cell DiseaseMast Cell Leukemia+1 more
Blueprint Medicines Corporation 86
Not applicableLooking for participantsNCT01137825
What this trial is testing

Registry of Older Patients With Cancer

Who this might be right for
Chronic Myeloproliferative DisordersCognitive/Functional EffectsLeukemia+6 more
UNC Lineberger Comprehensive Cancer Center 3,000
Testing effectiveness (Phase 2)Study completedNCT00109707
What this trial is testing

Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)Hypereosinophilic Syndrome+1 more
Novartis Pharmaceuticals 507
Not applicableStudy completedNCT00897767
What this trial is testing

Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial

Who this might be right for
LeukemiaLymphoma
Eastern Cooperative Oncology Group 1,873
Not applicableUnknownNCT06210698
What this trial is testing

Angioedema Biomarker Research Study

Who this might be right for
AngioedemaAngioedemas, HereditaryUrticaria+5 more
Foundation For Rare Disease Research 600
Not applicableStudy completedNCT01334996
What this trial is testing

Use of Tamoxifen in Systemic Mastocytosis

Who this might be right for
Systemic Mastocytosis
Mayo Clinic 1
Not applicableActive Not RecruitingNCT01199562
What this trial is testing

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

Who this might be right for
Hematopoietic/Lymphoid CancerAccelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated Leukemia+151 more
City of Hope Medical Center 153
Not applicableStudy completedNCT00001760
What this trial is testing

Cytokine Production Patterns in Patients With Systemic Mastocytosis Compared With Atopic Dermatitis and Healthy Individuals

Who this might be right for
Atopic DermatitisHealthyMastocytosis
National Institute of Allergy and Infectious Diseases (NIAID) 40
Not applicableActive Not RecruitingNCT06065007
What this trial is testing

Quality of Life and Disease-related Symptoms in Individuals With Systemic Mastocytosis

Who this might be right for
Mastocytosis, Systemic
Uppsala University 400
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT05186753
What this trial is testing

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Who this might be right for
SSMMastocytosis, IndolentMastocytosis, Systemic+5 more
Cogent Biosciences, Inc. 237
Testing effectiveness (Phase 2)Study completedNCT00233454
What this trial is testing

Phase 2 Midostaurin in Aggressive Systemic Mastocytosis and Mast Cell Leukemia

Who this might be right for
Systemic Mastocytosis, Aggressive (ASM)Leukemia, Mast CellHematological Non-mast Cell Lineage Disease (AHNMD)
Jason Robert Gotlib 26
Testing effectiveness (Phase 2)Study completedNCT00237627
What this trial is testing

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

Who this might be right for
Breast CancerLeukemiaLymphoma+3 more
UNC Lineberger Comprehensive Cancer Center 107
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