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Results for “Systemic Sclerosis - Diffuse Cutaneous”

71 trials

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Showing 20 of 71 results

Early research (Phase 1)Ended earlyNCT04478994
What this trial is testing

A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Amgen 3
Testing effectiveness (Phase 2)Study completedNCT03222492
What this trial is testing

Brentuximab Vedotin for Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic SclerosisSclerodermadcSSc
National Institute of Allergy and Infectious Diseases (NIAID) 17
Testing effectiveness (Phase 2)Study completedNCT02503644
What this trial is testing

Proof-of-concept Trial of IVA337 in Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, DiffuseDiffuse Cutaneous Systemic Sclerosis
Inventiva Pharma 145
Not applicableStudy completedNCT01758250
What this trial is testing

Microvascular and Fibrosis Imaging Study

Who this might be right for
Autoimmune DiseasesSickle Cell DiseaseChronic Graft Versus Host Disease
Duke University 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT02682511
What this trial is testing

Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

Who this might be right for
Scleroderma, DiffuseScleroderma, SystemicScleroderma, Limited+5 more
Cumberland Pharmaceuticals 34
Testing effectiveness (Phase 2)Looking for participantsNCT03844061
What this trial is testing

Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Hospital for Special Surgery, New York 30
Not applicableLooking for participantsNCT03276923
What this trial is testing

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

Who this might be right for
Autoimmune DiseasesPregnancy RelatedSystemic Lupus Erythematosus+4 more
Duke University 1,000
Not applicableLooking for participantsNCT06387654
What this trial is testing

Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases

Who this might be right for
Autoimmune Bullous DermatosisDysimmune Dermatological DiseasesAuto-inflammatory Dermatological Diseases+1 more
University Hospital, Toulouse 800
Not applicableAvailableNCT04432545
What this trial is testing

Infusion of Allogeneic Mesenchymal Stem Cells in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement

Who this might be right for
Systemic Sclerosis PulmonaryPulmonary HypertensionPulmonary Fibrosis
Universidad de la Sabana
Post-approval studies (Phase 4)Study completedNCT07472166
What this trial is testing

Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

Who this might be right for
Scleroderma, Systemic
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 34
Early research (Phase 1)Active Not RecruitingNCT06152172
What this trial is testing

CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101

Who this might be right for
Idiopathic Inflammatory MyopathiesDiffuse Cutaneous Systemic SclerosisSLE Nephritis+1 more
David Porter 24
Testing effectiveness (Phase 2)Study completedNCT07542067
What this trial is testing

Infusion of Allogeneic Stromal Mesenchymal Stem Cells From Wharton´s Jelly in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement to Treatment

Who this might be right for
Systemic Sclerosis PulmonaryPulmonary HypertensionPulmonary Fibrosis
Fundación Neumologica Colombiana 1
Large-scale testing (Phase 3)Ended earlyNCT03398837
What this trial is testing

Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Corbus Pharmaceuticals Inc. 365
Not applicableStudy completedNCT00476801
What this trial is testing

UVA1 Light for Treatment of Scleroderma and Similar Conditions

Who this might be right for
SclerodermaKeloidsOther Fibrosing Conditions
University of Michigan 27
Testing effectiveness (Phase 2)Study completedNCT03041025
What this trial is testing

Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Systemic
GlaxoSmithKline 35
Testing effectiveness (Phase 2)Ended earlyNCT04781543
What this trial is testing

Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic SclerosisSclerosis, Systemic
Amgen 301
Early research (Phase 1)Study completedNCT02426229
What this trial is testing

Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma

Who this might be right for
SclerodermaInterstitial Lung Disease
Medical University of South Carolina 15
Large-scale testing (Phase 3)Looking for participantsNCT06716606
What this trial is testing

Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

Who this might be right for
Connective Tissue Diseases
GlaxoSmithKline 514
Testing effectiveness (Phase 2)UnknownNCT00769028
What this trial is testing

AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Daval International Limited 20
Testing effectiveness (Phase 2)Ended earlyNCT04837131
What this trial is testing

Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients

Who this might be right for
Systemic SclerosisSclerodermaDiffuse Systemic Sclerosis+16 more
Michael M. Pham 4
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