Testing effectiveness (Phase 2)Ended earlyNCT03993613What this trial is testingApotransferrin in Patients With β-thalassemiaWho this might be right forβ-thalassemia Intermedia Prothya Biosolutions 10
Not applicableActive Not RecruitingNCT05860595What this trial is testingEvaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.Who this might be right forTransfusion-dependent Beta-Thalassemia Institute of Hematology & Blood Diseases Hospital, China 3
Early research (Phase 1)Study completedNCT02712346What this trial is testingThe Role of Endothelin-1 in Sickle Cell DiseaseWho this might be right forSickle Cell Anemia Augusta University 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT06490601What this trial is testingLong Term Beta Thalassemia Treatment: Findings From The Extension PeriodWho this might be right forFetal HemoglobinBeta-ThalassemiaHemoglobinopathies National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 30
Testing effectiveness (Phase 2)Looking for participantsNCT05735717What this trial is testingMT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme MalignanciesWho this might be right forHematologic MalignancyAcute LeukemiaRemission+21 more Masonic Cancer Center, University of Minnesota 70
Not applicableUnknownNCT05105659What this trial is testingAssessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.Who this might be right forB Thalassemia Assiut University 60
Testing effectiveness (Phase 2)Study completedNCT01749540What this trial is testingStudy to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)Who this might be right forB-Thalassemia Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Early research (Phase 1)Looking for participantsNCT06647979What this trial is testingHematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-HemoglobinopathiesWho this might be right forSickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Beta-Thalassemia+1 more Daniel Bauer 10
Not applicableUnknownNCT04962984What this trial is testingThrombin Generation in Beta-thalassemia MajorWho this might be right forBeta Thalassemia Major Anemia Central Hospital, Nancy, France 45
Not applicableNot Yet RecruitingNCT07614217What this trial is testingOral Health Status in Children With β-Thalassemia MajorWho this might be right forB Thalassemia Major Cairo University 45
Testing effectiveness (Phase 2)UnknownNCT03183375What this trial is testingThe Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi PakistanWho this might be right forThalassemia, Beta Dr.Saqib Hussain Ansari 100
Not applicableStudy completedNCT05529550What this trial is testingAssessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in ChildrenWho this might be right forThalassemia Menoufia University 102
Testing effectiveness (Phase 2)Ended earlyNCT01571635What this trial is testingStudy to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.Who this might be right forBeta Thalassemia MajorBeta Thalassemia Intermedia Celgene 46
Testing effectiveness (Phase 2)Looking for participantsNCT04143724What this trial is testingStudy of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-ThalassemiaWho this might be right forBeta-Thalassemia Celgene 99
Not applicableStudy completedNCT04691323What this trial is testingThe Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.Who this might be right forSickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more Ann & Robert H Lurie Children's Hospital of Chicago 68
Not applicableUnknownNCT05133388What this trial is testingThe Prevelence of HBB c.93-21 G-A in β Thalassemia PatientsWho this might be right forBeta-Thalassemia Assiut University 150
Not applicableStudy completedNCT04675645What this trial is testingAdherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go AppWho this might be right forSickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more Ann & Robert H Lurie Children's Hospital of Chicago 33
Not applicableActive Not RecruitingNCT06875219What this trial is testingTo Evaluate Long- Term Safety and Efficacy of LuspaterceptWho this might be right forThalassemia Major Fondazione per la Ricerca sulle Anemie ed Emoglobinopatie in Italia 350
Very early researchEnrolling By InvitationNCT06328764What this trial is testingCS-101 in Patients With β-thalassemiaWho this might be right forBeta-Thalassemia CorrectSequence Therapeutics Co., Ltd 10
Testing effectiveness (Phase 2)Study completedNCT07292259What this trial is testingCombination of Thalidomide and Hydroxyuria in Transfusion Dependent ThalasemmiaWho this might be right forTransfusion Dependent Beta Thalassemia Pakistan Blood and Marrow Transplant (PBMT) Group 100