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Results for “TOR Serine-Threonine Kinases”

37 trials

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Showing 20 of 37 results

Testing effectiveness (Phase 2)Study completedNCT02093598
What this trial is testing

POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus

Who this might be right for
Carcinoma, EndometrioidmTOR Protein
MedSIR 10
Post-approval studies (Phase 4)Study completedNCT01046045
What this trial is testing

Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients

Who this might be right for
Chronic Allograft Dysfunction in Renal Transplantation
Chinese University of Hong Kong 17
Large-scale testing (Phase 3)Study completedNCT00790400
What this trial is testing

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous Sclerosis Complex (TSC)Lymphangioleiomyomatosis (LAM)
Novartis Pharmaceuticals 118
Testing effectiveness (Phase 2)Study completedNCT00457964
What this trial is testing

RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM

Who this might be right for
Tuberous SclerosisLymphangioleiomyomatosis
Children's Hospital Medical Center, Cincinnati 36
Post-approval studies (Phase 4)Study completedNCT01935128
What this trial is testing

Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction

Who this might be right for
Renal Transplant
University of Toledo Health Science Campus 55
Testing effectiveness (Phase 2)Ended earlyNCT00877773
What this trial is testing

Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin (PI3K-mTOR) in Advanced Cancer Patients

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 44
Testing effectiveness (Phase 2)Study completedNCT00411619
What this trial is testing

Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

Who this might be right for
Tuberous SclerosisSubependymal Giant Cell Astrocytoma
Children's Hospital Medical Center, Cincinnati 28
Early research (Phase 1)Study completedNCT00731263
What this trial is testing

Tor Kinase Inhibitor in Advanced Tumors

Who this might be right for
Solid Tumors
AstraZeneca 64
Testing effectiveness (Phase 2)WithdrawnNCT01188889
What this trial is testing

RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.

Who this might be right for
Chronic Myeloid Leukemia
University of Michigan Rogel Cancer Center
Not applicableUnknownNCT03486366
What this trial is testing

Application of Novel Diagnostic and Therapeutical Methods in Epilepsy and Neurodevelopmental Abnormalities in Children.

Who this might be right for
Epilepsy
Medical University of Warsaw 120
Testing effectiveness (Phase 2)Study completedNCT00093080
What this trial is testing

Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

Who this might be right for
LeiomyosarcomaLiposarcomaOsteosarcoma+2 more
Merck Sharp & Dohme LLC 216
Testing effectiveness (Phase 2)UnknownNCT01960829
What this trial is testing

Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety Study

Who this might be right for
MelanomaTOR Serine-Threonine KinasesNeoplasm Metastasis
Peking University Cancer Hospital & Institute 60
Not applicableStudy completedNCT01632605
What this trial is testing

The Vienna RAP Pilot Study

Who this might be right for
ADPKD
Medical University of Vienna 8
Early research (Phase 1)Study completedNCT01353625
What this trial is testing

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

Who this might be right for
Glioblastoma MultiformeSquamous Cell Carcinoma of Head and NeckProstate Cancer+3 more
Celgene 118
Testing effectiveness (Phase 2)Study completedNCT02874924
What this trial is testing

Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly

Who this might be right for
Aging
The University of Texas Health Science Center at San Antonio 34
Post-approval studies (Phase 4)Ended earlyNCT01561404
What this trial is testing

Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise

Who this might be right for
Disorder Related to Renal TransplantationExercise, AerobicMuscle Strength
Josep M Cruzado 3
Large-scale testing (Phase 3)UnknownNCT02055079
What this trial is testing

Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease

Who this might be right for
Polycystic Kidney, Type 1 Autosomal Dominant DiseasePolycystic Kidney, Type 2 Autosomal Dominant Disease
Medical University of Vienna 68
Testing effectiveness (Phase 2)Enrolling By InvitationNCT05285878
What this trial is testing

Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

Who this might be right for
Interstitial FibrosisKidney Transplant; ComplicationsKidney Transplant Rejection+4 more
The Methodist Hospital Research Institute 20
Large-scale testing (Phase 3)UnknownNCT03987152
What this trial is testing

Treatment of Congenital Vascular Malformations Using Sirolimus: Improving Quality of Life

Who this might be right for
Vascular Malformations
Radboud University Medical Center 75
Early research (Phase 1)WithdrawnNCT01194193
What this trial is testing

Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours

Who this might be right for
CancerAdvanced Solid TumoursLymphomas
AstraZeneca 63
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