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Results for “TP53”

205 trials

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Showing 20 of 205 results

Testing effectiveness (Phase 2)Ended earlyNCT02612285
What this trial is testing

Study of SNX-5422 in TP53 Null Cancers

Who this might be right for
Cancer
Esanex Inc. 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT03781986
What this trial is testing

APG-115 in Salivary Gland Cancer Trial

Who this might be right for
Malignant Salivary Gland CancerSalivary Gland Cancer
University of Michigan Rogel Cancer Center 41
Early research (Phase 1)Study completedNCT06054464
What this trial is testing

Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants

Who this might be right for
Healthy Volunteers
PMV Pharmaceuticals, Inc 28
Not applicableNot Yet RecruitingNCT06900582
What this trial is testing

SENTInel Node Mapping Versus Comprehensive Lymphadenectomy in p53-Mutated Endometrial Cancer: A Non-Inferiority Randomized Trial

Who this might be right for
LymphadenectomyEndometrial CancerGene, p53+1 more
University Hospital, Strasbourg, France 374
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07150416
What this trial is testing

Nebulized Inhalation of Recombinant Human p53 Adenovirus Injection for Treatment of Multiple Ground-Glass Lung Nodules: A Single-Arm Clinical Study

Who this might be right for
Multiple Pulmonary Ground-Glass NodulesLung NeoplasmsPrecancerous Conditions
The First Affiliated Hospital of Guangzhou Medical University 38
Early research (Phase 1)Ended earlyNCT03940352
What this trial is testing

HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome (MDS)
Novartis Pharmaceuticals 52
Not applicableActive Not RecruitingNCT07303218
What this trial is testing

The HER Project: HRD in EGFR-mutated NSCLC

Who this might be right for
EGFRNon Small Cell Lung CancerHomologous Recombination Deficiency+1 more
IRCCS San Raffaele 100
Testing effectiveness (Phase 2)UnknownNCT02509169
What this trial is testing

Trans-catheter Arterial Embolization Combined With p53 Gene Therapy for Treatment of Advanced Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular Carcinoma (HCC)
Shenzhen SiBiono GeneTech Co.,Ltd 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT02965950
What this trial is testing

The p53 Breast Cancer Trial

Who this might be right for
Locally Advanced Breast CancerMetastatic Breast Carcinoma
Haukeland University Hospital 190
Testing effectiveness (Phase 2)UnknownNCT04358393
What this trial is testing

APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS

Who this might be right for
AMLAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia+4 more
Ascentage Pharma Group Inc. 69
Early research (Phase 1)Ended earlyNCT02577588
What this trial is testing

Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer

Who this might be right for
Colorectal Carcinoma
National Center for Tumor Diseases, Heidelberg 1
Not applicableUnknownNCT03524677
What this trial is testing

Mutation of K-RAS, CDKN2A, SMAD4 and TP53 in Pancreatic Cancer: Role of Liquid Biopsy in Preoperative Diagnosis

Who this might be right for
Pancreatic Cancer
University of Roma La Sapienza 50
Not applicableStudy completedNCT04872036
What this trial is testing

Prognostic Biomarkers in Patients With Urothelial Carcinoma

Who this might be right for
Bladder Cancer
Hellenic Cooperative Oncology Group 66
Testing effectiveness (Phase 2)Study completedNCT01164995
What this trial is testing

Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer

Who this might be right for
Epithelial Ovarian Cancer
The Netherlands Cancer Institute 24
Not applicableStudy completedNCT02827617
What this trial is testing

Identification of Biomarkers That Are Predictive of Early Ibrutinib Treatment Failure in High Risk TP53 Mutated Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
Oncology Institute of Southern Switzerland 56
Testing effectiveness (Phase 2)UnknownNCT02418988
What this trial is testing

Trans-catheter Chemo-embolization Combined With rAd-p53 Gene Injection in Treatment of Advanced Hepatocellular Carcinoma

Who this might be right for
Advanced Adult Hepatocellular Carcinoma
Shenzhen SiBiono GeneTech Co.,Ltd 120
Not applicableNot Yet RecruitingNCT06521684
What this trial is testing

Translational Study of MSS, TP53 Mutation and Chromosome Instability Relationship in Endometrial Carcinoma

Who this might be right for
Endometrial NeoplasmsTP53 Gene MutationChromosomal Instability+1 more
Peking Union Medical College Hospital 110
Not applicableStudy completedNCT01954134
What this trial is testing

P53 in Differentiated Thyroid Cancer

Who this might be right for
Thyroid Neoplasms
Cumhuriyet University 199
Testing effectiveness (Phase 2)UnknownNCT04533321
What this trial is testing

A Biomarker-implemented Clinical Study Evaluating Mutations in MET and TP53 in a Population of Treatment-refractory Squamous Cell Carcinoma

Who this might be right for
Squamous Cell Carcinoma
National University Hospital, Singapore 20
Large-scale testing (Phase 3)Study completedNCT02756611
What this trial is testing

Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic Leukemia
AbbVie 258
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