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Results for “TP53 R175H”

4 trials

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Showing 4 of 4 results

Early research (Phase 1)Looking for participantsNCT05877599
What this trial is testing

NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Who this might be right for
Non-small Cell Lung CancerHead and Neck Squamous Cell CarcinomaColorectal Carcinoma+4 more
AstraZeneca 45
Testing effectiveness (Phase 2)WithdrawnNCT06690281
What this trial is testing

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Who this might be right for
Gastrointestinal CarcinomaPancreatic CancerHepatocellular Cancer+5 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT06778863
What this trial is testing

CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorMetastatic Solid Tumor+8 more
Clasp Therapeutics, Inc. 90
Early research (Phase 1)Looking for participantsNCT05631886
What this trial is testing

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

Who this might be right for
Solid Tumor, AdultLymphomaEphA2 Overexpression+4 more
Chinese PLA General Hospital 10