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Results for “TP53 Y220C Mutation”

6 trials

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Showing 6 of 6 results

Early research (Phase 1)Looking for participantsNCT06908434
What this trial is testing

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation

Who this might be right for
Solid Tumors Harboring a TP53 Y220C Mutation
Changchun GeneScience Pharmaceutical Co., Ltd. 82
Early research (Phase 1)Study completedNCT06054464
What this trial is testing

Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants

Who this might be right for
Healthy Volunteers
PMV Pharmaceuticals, Inc 28
Early research (Phase 1)Looking for participantsNCT07372625
What this trial is testing

Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Who this might be right for
TP53 Y220C MutationAdvanced Solid Tumors
PMV Pharmaceuticals, Inc 14
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07060989
What this trial is testing

Safety, Tolerability and Preliminary Efficacy of NTS071 in Subjects With Advanced Solid Tumors Harboring a TP53 Y220C Mutation

Who this might be right for
Advanced Solid Tumors
Nutshell Therapeutics (Shanghai) Co., LTD. 220
Testing effectiveness (Phase 2)Looking for participantsNCT06386146
What this trial is testing

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Who this might be right for
Solid Tumors
Jacobio Pharmaceuticals Co., Ltd. 144
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300