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Results for “TTR Cardiomyopathy”

122 trials

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Showing 20 of 122 results

Not applicableStudy completedNCT06393465
What this trial is testing

Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 50
Not applicableActive Not RecruitingNCT06257485
What this trial is testing

Bronx Transthyretin Amyloid Cardiomyopathy Database

Who this might be right for
Transthyretin Cardiac AmyloidosisTransthyretin Amyloid Cardiomyopathy
Montefiore Medical Center 476
Testing effectiveness (Phase 2)UnknownNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Not applicableLooking for participantsNCT06291805
What this trial is testing

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloid CardiomyopathyWild-Type Transthyretin-Related (ATTR)Amyloidosis+1 more
Steen Hvitfeldt Poulsen 120
Not applicableLooking for participantsNCT07358078
What this trial is testing

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 2,000
Not applicableNot Yet RecruitingNCT07591038
What this trial is testing

PET/CT Imaging in Carriers of TTR Mutations

Who this might be right for
ATTRATTR Gene MutationCardiomyopathy+1 more
University of Texas Southwestern Medical Center 80
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149
What this trial is testing

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 655
Not applicableLooking for participantsNCT06887283
What this trial is testing

Essen Amyloidosis Registry

Who this might be right for
Amyloidosis; SystemicAmyloidosis Cardiac
University Hospital, Essen 400
Large-scale testing (Phase 3)Study completedNCT01994889
What this trial is testing

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 441
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Very early researchLooking for participantsNCT06082050
What this trial is testing

Efficacy and Safety of Intravenous YOLT-201 for Transthyretin Amyloidosis Cardiomyopathy

Who this might be right for
Transthyroxin Amyloidosis Cardiomyopathy
Zhejiang University 7
Large-scale testing (Phase 3)Looking for participantsNCT06128629
What this trial is testing

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics 1,200
Testing effectiveness (Phase 2)Ended earlyNCT03702829
What this trial is testing

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Who this might be right for
Amyloidosis
Brigham and Women's Hospital 31
Testing effectiveness (Phase 2)Study completedNCT03458130
What this trial is testing

Study of AG10 in Amyloid Cardiomyopathy

Who this might be right for
Familial ATTR-CM (ATTRm-CM, or FAC)Wild-type ATTR-CM (ATTRwt-CM)
Eidos Therapeutics, a BridgeBio company 49
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Testing effectiveness (Phase 2)Looking for participantsNCT06634108
What this trial is testing

Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 20
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
Post-approval studies (Phase 4)Study completedNCT04814186
What this trial is testing

Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Pfizer 53
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Not applicableEnrolling By InvitationNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
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