Large-scale testing (Phase 3)Ended earlyNCT01264887What this trial is testingTapentadol in Chronic Malignant Tumour Related PainWho this might be right forCancerChronic PainPain Grünenthal GmbH 31
Large-scale testing (Phase 3)Study completedNCT00983385What this trial is testingEvaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular AnalgesicsWho this might be right forChronic PainLow Back Pain Grünenthal GmbH 208
Large-scale testing (Phase 3)Study completedNCT02604446What this trial is testingDepot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs PlaceboWho this might be right forJoint Diseases St. Olavs Hospital 134
Large-scale testing (Phase 3)Study completedNCT01309386What this trial is testingA Safety and Efficacy Study of Oral Tapentadol Extended-Release in Japanese ParticipantsWho this might be right forNeoplasms Janssen Pharmaceutical K.K. 100
Large-scale testing (Phase 3)Ended earlyNCT01063868What this trial is testingA Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)Who this might be right forDiabetic Neuropathy, PainfulDiabetic Polyneuropathy Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 47
Testing effectiveness (Phase 2)Ended earlyNCT02221674What this trial is testingUse of Tapentadol Oral Solution for Pain After Surgery in Children From Newborn to Less Than 2 Years OldWho this might be right forModerate to Severe Acute Postoperative Pain Grünenthal GmbH 40
Not applicableUnknownNCT04718116What this trial is testingTapentadol Versus Tramadol Analgesia Post Cardiac SurgeryWho this might be right forPostoperative PainSurgeryPain, Postoperative+5 more Aretaieion University Hospital 90
Large-scale testing (Phase 3)Study completedNCT00449176What this trial is testingEvaluate the Effectiveness and Safety of Tapentadol (CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back PainWho this might be right forLow Back Pain Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 981
Large-scale testing (Phase 3)Study completedNCT01041859What this trial is testingEvaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral NeuropathyWho this might be right forDiabetic Peripheral Neuropathy Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 460
Not applicableWithdrawnNCT01719588What this trial is testingA Safety and Effectiveness Study of Prolonged Release Tapentadol Hydrochloride Among Filipino Patients With Moderate to Severe Chronic Non-Cancer PainWho this might be right forModerate to Severe Chronic Non-cancer Pain Janssen Pharmaceutica
Large-scale testing (Phase 3)Study completedNCT00472303What this trial is testingEvaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and MorphineWho this might be right forTumorPain Grünenthal GmbH 622
Not applicableStudy completedNCT07320781What this trial is testingRole of Preoperative Tapentadol in Reduction of Perioperative Analgesic Requirement After Breast Conservative Surgery in Cancer Patients.Who this might be right forBreast Cancer Shaukat Khanum Memorial Cancer Hospital & Research Centre 70
Post-approval studies (Phase 4)Ended earlyNCT01458015What this trial is testingTapentadol Versus Oxycodone - a Mechanism-based Treatment Approach in Neuropathic PainWho this might be right forPeripheral Neuropathy University Hospital Schleswig-Holstein 3
Large-scale testing (Phase 3)Ended earlyNCT00986258What this trial is testingEvaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of TolerabilityWho this might be right forPainChronic PainLow Back Pain+2 more Grünenthal GmbH 136
Large-scale testing (Phase 3)Study completedNCT00478023What this trial is testingEvaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal HysterectomyWho this might be right forHysterectomyPostoperative Grünenthal GmbH 854
Post-approval studies (Phase 4)Study completedNCT03604354What this trial is testingSafety and Efficacy of Pre-emptive Tapentadol vs Pregabalin in Post Operative Pain Following SurgeryWho this might be right forOsteoarthritis, Knee All India Institute of Medical Sciences, Bhubaneswar 95
Post-approval studies (Phase 4)Study completedNCT01352741What this trial is testingComparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and PregabalinWho this might be right forLow Back PainNeuropathic Pain Grünenthal GmbH 622
Large-scale testing (Phase 3)Study completedNCT00983073What this trial is testingEvaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular AnalgesicWho this might be right forChronic PainOsteoarthritis Grünenthal GmbH 224
Early research (Phase 1)Study completedNCT01900587What this trial is testingA Pivotal Study to Evaluate the Bio-equivalence of the Tapentadol Extended-Release (ER) Tamper-resistant Formulation (TRF) Tablet to the Current Tapentadol ER Prolonged-release 2 (PR2) TabletWho this might be right forHealthy Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 64
Post-approval studies (Phase 4)Study completedNCT01838616What this trial is testingTapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.Who this might be right forBack PainLow Back PainNeuropathic Pain Grünenthal GmbH 367