Not applicableNot Yet RecruitingNCT06440603What this trial is testingEKLF Gene Expression in β-thalassemiaWho this might be right forβ-thalassemia Rofaida Hassan Ahmed 150
Testing effectiveness (Phase 2)Study completedNCT01709032What this trial is testingCombination Deferasirox and Deferiprone for Severe Iron Overload in ThalassemiaWho this might be right forThalassemia Major With Severe Transfusional Iron Overload Children's Hospital of Philadelphia 9
Early research (Phase 1)Ended earlyNCT02274233What this trial is testingSafety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-ThalassemiaWho this might be right forIron OverloadBeta-Thalassemia Sideris Pharmaceuticals 24
Post-approval studies (Phase 4)Study completedNCT02342145What this trial is testingEfficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia MajorWho this might be right forBeta-Thalassemia MajorGraft-versus-host Disease (GVHD) Zhongming Zhang 205
Early research (Phase 1)Active Not RecruitingNCT03249831What this trial is testingA Blood Stem Cell Transplant for Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell DisorderHemoglobinopathies+2 more City of Hope Medical Center 3
Not applicableUnknownNCT03881917What this trial is testingCystatin c and Beta 2 Microglobulin in Thalassemic Children.Who this might be right forBlood Disease Assiut University 150
Very early researchStudy completedNCT06065189What this trial is testingBase-edited Autologous Hematopoietic Stem Cell Transplantation in Treating Patients With β-thalassemia MajorWho this might be right forBeta-Thalassemia Children's Hospital of Fudan University 2
Testing effectiveness (Phase 2)Study completedNCT07292259What this trial is testingCombination of Thalidomide and Hydroxyuria in Transfusion Dependent ThalasemmiaWho this might be right forTransfusion Dependent Beta Thalassemia Pakistan Blood and Marrow Transplant (PBMT) Group 100
Testing effectiveness (Phase 2)Ended earlyNCT04059406What this trial is testingStudy to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)Who this might be right forBeta Thalassemia Intermedia Ionis Pharmaceuticals, Inc. 29
Not applicableStudy completedNCT01319552What this trial is testingFresh Versus Old Red Blood Cells for TransfusionWho this might be right forIron, Abnormal Blood LevelOther Abnormal Blood Chemistry Columbia University 14
Not applicableStudy completedNCT07486531What this trial is testingIron Accumulation in Erythrocytes in PatientsWho this might be right forBeta Thalassemia Major Ankara City Hospital Bilkent 100
Testing effectiveness (Phase 2)Ended earlyNCT02504619What this trial is testingAllogeneic SCT of CordIn™, in Patients With HemoglobinopathiesWho this might be right forSickle Cell DiseaseThalassemia Gamida Cell ltd 1
Not applicableStudy completedNCT00481039What this trial is testingSickle Cell Anemia in an Arab Bedouin Village in the Northern IsraelWho this might be right forSickle Cell Disease HaEmek Medical Center, Israel 300
Post-approval studies (Phase 4)Looking for participantsNCT07177300What this trial is testingEffectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)Who this might be right forSickle Cell Anemia (HbSS)Sickle-β0-thalassemia (HbSβ0) Children's Hospital Medical Center, Cincinnati 50
Not applicableStudy completedNCT02197845What this trial is testingEnhancing Use of Hydroxyurea In Sickle Cell Disease Using Patient NavigatorsWho this might be right forSickle Cell Disease Virginia Commonwealth University 353
Post-approval studies (Phase 4)Study completedNCT00105495What this trial is testingEfficacy Study in Removing Excess Iron From the HeartWho this might be right forThalassemia MajorHemosiderosis ApoPharma 60
Post-approval studies (Phase 4)Study completedNCT03117192What this trial is testingZinc Supplementation on Cellular Immunity in Thalassemia MajorWho this might be right forThalassemiaSplenectomy; StatusImmunosuppression Fakultas Kedokteran Universitas Indonesia 58
Not applicableStudy completedNCT03161899What this trial is testingEvaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children HospitalWho this might be right forThalassemia Major Assiut University 246
Not applicableUnknownNCT02761395What this trial is testingStudy of The Therapeutic Benefits of Al-hijamah in Children With Beta Thalassemia MajorWho this might be right forAL-Hijama in Thalassmia Major Tanta University 60
Testing effectiveness (Phase 2)Study completedNCT01590628What this trial is testingAllogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With HemoglobinopathiesWho this might be right forSickle Cell Disease & Thalassemia Gamida Cell ltd 16