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Results for “Tirumotecan”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511023
What this trial is testing

Phase 2 Trial Of Sacituzumab Tirumotecan For Treatment Of Refractory Metastatic Or Unresectable Squamous Cell Carcinoma Of The Anus/Rectum

Who this might be right for
Phase 2Sacituzumab TirumotecanRefractory Metastatic+2 more
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07689292
What this trial is testing

Sac-TMT Combined With Fruquintinib as Second-Line Treatment in Patients With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction (GEJ) AdenocarcinomaGastro-esophageal Junction Adenocarcinoma
Tianjin Medical University Cancer Institute and Hospital 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07197008
What this trial is testing

Sacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain Metastasis

Who this might be right for
Lung Cancer
Li-kun Chen 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07823270
What this trial is testing

Neoadjuvant Sacituzumab Tirumotecan Plus Toripalimab in Locally Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 33
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07521670
What this trial is testing

Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP)

Who this might be right for
Recurrent Adenoid Cystic CarcinomaAdenoid Cystic Carcinoma MetastaticPapillary Thyroid Carcinoma
National Cancer Centre, Singapore 68
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07639086
What this trial is testing

Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy

Who this might be right for
Prostate CancerNeuroendocrine Prostate Cancer (NEPC)
Virginia Commonwealth University 20
Testing effectiveness (Phase 2)Looking for participantsNCT07375316
What this trial is testing

A ctDNA-guided Phase II Trial of Osimertinib in Combination With Sacituzumab Tirumotecan in EGFR-mutated Advanced NSCLC Patients With Positive ctDNA After lead-in Osimertinib Monotherapy

Who this might be right for
Non Small Cell Lung Cancer
Guangdong Association of Clinical Trials 120
Large-scale testing (Phase 3)Looking for participantsNCT06393374
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Who this might be right for
Triple-Negative Breast Cancer
Merck Sharp & Dohme LLC 1,530
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07348861
What this trial is testing

A Phase II Study of Neoadjuvant Sacituzumab Tirumotecan in Combination With Iparomlimab and Tuvonralimab in Locally Advanced Cervical Cancer

Who this might be right for
Cervical Cancer
Zheng Min 25
Testing effectiveness (Phase 2)Looking for participantsNCT07324629
What this trial is testing

Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic Carcinoma

Who this might be right for
Thymic Carcinoma
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 30
Large-scale testing (Phase 3)Looking for participantsNCT06841354
What this trial is testing

Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Who this might be right for
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT07371208
What this trial is testing

Multicenter, Phase II Clinical Study of Sacituzumab Tirumotecan (Sac-TMT) in Combination With KL-A167 for Neoadjuvant Treatment of Triple-Negative Breast Cancer

Who this might be right for
Breast Cancer
Shanghai Jiao Tong University School of Medicine 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07388875
What this trial is testing

Sacituzumab Tirumotecan Plus Anlotinib in Previously Treated ES-SCLC

Who this might be right for
Extensive-Stage Small Cell Lung Cancer
China Medical University, China 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07686588
What this trial is testing

Sacituzumab Tirumotecan Plus Immunotherapy for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent or Metastatic Head and Neck Carcinoma
Biying Chen 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07438600
What this trial is testing

Study of Sacituzumab Tirumotecan Combined With Toripalimab for Resectable Stage II-IIIB NSCLC

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Tianjin Medical University Cancer Institute and Hospital 38
Large-scale testing (Phase 3)Looking for participantsNCT06422143
What this trial is testing

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Who this might be right for
Non-small Cell Lung CancerNSCLC
Merck Sharp & Dohme LLC 851
Large-scale testing (Phase 3)Looking for participantsNCT06952504
What this trial is testing

Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Who this might be right for
Endometrial Cancer
Merck Sharp & Dohme LLC 1,123
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07244874
What this trial is testing

Sac-TMT Combined With Toripalimab for First-line Treatment of PD-L1 Positive a/mTNBC

Who this might be right for
TNBC - Triple-Negative Breast CancerPD-L1 Positive
Tianjin Medical University Cancer Institute and Hospital 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07716917
What this trial is testing

Genitourinary Tumors With Sacituzumab Tirumotecan

Who this might be right for
Papillary Renal CarcinomaVariant Histology Urothelial Carcinoma
Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07720258
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) in Patients With Advanced Small Bowel Adenocarcinoma Refractory or Intolerant to Platinum-Based Combination Therapy

Who this might be right for
Advanced Small Bowel Adenocarcinoma
National Cancer Center, Japan 27
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