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Results for “Transformed Lymphoma / DLBCL”

49 trials

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Showing 20 of 49 results

Testing effectiveness (Phase 2)Ended earlyNCT02572453
What this trial is testing

Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL

Who this might be right for
Recurrent Anaplastic Large Cell LymphomaRecurrent Diffuse Large B-Cell LymphomaRecurrent Mantle Cell Lymphoma+5 more
National Cancer Institute (NCI) 25
Testing effectiveness (Phase 2)Looking for participantsNCT04889716
What this trial is testing

CAR-T Followed by Bispecific Antibodies

Who this might be right for
Large B-cell LymphomaDLBCL - Diffuse Large B Cell Lymphoma
Abramson Cancer Center at Penn Medicine 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT03162536
What this trial is testing

Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

Who this might be right for
Lymphoma, B-CellSmall Lymphocytic LymphomaChronic Lymphocytic Leukemia+6 more
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 190
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583149
What this trial is testing

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Who this might be right for
Refractory Aggressive B-cell LymphomasRefractory B-Cell Non-Hodgkin LymphomaAggressive B-cell NHL+10 more
Patrick C. Johnson, MD 28
Testing effectiveness (Phase 2)Ended earlyNCT02378038
What this trial is testing

PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)

Who this might be right for
Richter's Transformation
Sierra Oncology LLC - a GSK company 5
Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Large-scale testing (Phase 3)Study completedNCT01321541
What this trial is testing

Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant

Who this might be right for
Diffuse Large B-cell Lymphomade Novo DLBCLDLBCL Transformed From Indolent Lymphoma+1 more
CTI BioPharma 312
Testing effectiveness (Phase 2)Study completedNCT00532259
What this trial is testing

CT-011 MAb in DLBCL Patients Following ASCT

Who this might be right for
Lymphoma, Large Cell, DiffuseLymphoma, Mixed Cell, DiffusePrimary Mediastinal Large B-Cell Lymphoma
CureTech Ltd 72
Testing effectiveness (Phase 2)Ended earlyNCT05328102
What this trial is testing

Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large-cell B-cell Lymphoma
Xencor, Inc. 3
Testing effectiveness (Phase 2)Looking for participantsNCT06743945
What this trial is testing

POLA-R-CHP in the First-line Treatment of Transformed DLBCL

Who this might be right for
Transformed Lymphoma
Fudan University 20
Testing effectiveness (Phase 2)UnknownNCT04796857
What this trial is testing

Tislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL

Who this might be right for
Non-GCB/ABC Diffuse Large B-Cell LymphomaHigh-grade B-cell LymphomaFollicular Lymphoma Grade IIIb+3 more
Huiqiang Huang 30
Early research (Phase 1)Active Not RecruitingNCT05828589
What this trial is testing

BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

Who this might be right for
Relapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin LymphomaRelapsed Chronic Lymphocytic Leukemia+11 more
BeiGene 112
Early research (Phase 1)Study completedNCT04450069
What this trial is testing

CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies

Who this might be right for
Relapsed/Refractory B-cell LymphomasDiffuse Large B Cell Lymphoma (DLBCL)Follicular Lymphoma (FL)+9 more
Calibr, a division of Scripps Research 18
Testing effectiveness (Phase 2)Study completedNCT01665768
What this trial is testing

Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma

Who this might be right for
CD20+, B-cell LymphomasMantle Cell LymphomaNon-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL)+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 56
Early research (Phase 1)Ended earlyNCT05169489
What this trial is testing

BbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)
Regeneron Pharmaceuticals 15
Testing effectiveness (Phase 2)UnknownNCT04058470
What this trial is testing

Toripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma

Who this might be right for
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaFollicular Lymphoma Grade IIIb+3 more
Huiqiang Huang 140
Early research (Phase 1)Ended earlyNCT04806035
What this trial is testing

Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia

Who this might be right for
CLLSLLRichter's Transformation+7 more
TG Therapeutics, Inc. 21
Early research (Phase 1)Looking for participantsNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Testing effectiveness (Phase 2)WithdrawnNCT02653989
What this trial is testing

Efficacy and Safety Study of MDV9300 in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
Lymphoma, Large B-Cell, DiffusePrimary Mediastinal Large B-cell LymphomaTransformed Indolent Lymphoma
Medivation, Inc.
Testing effectiveness (Phase 2)Temporarily pausedNCT03704714
What this trial is testing

Nivolumab and Combination Chemotherapy in Treating Participants With Diffuse Large B-Cell Lymphoma

Who this might be right for
Aggressive Non-Hodgkin LymphomaB-Cell Non-Hodgkin LymphomaCD20 Positive+5 more
Northwestern University 30
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