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Results for “Transfusion Dependent Beta-Thalassaemia”

93 trials

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Showing 20 of 93 results

Not applicableStudy completedNCT06509581
What this trial is testing

Vitamin E Supplementation for Children With Transfusion Dependent Beta Thalassemia on Different Iron Chelation Regimen

Who this might be right for
Beta-Thalassemia
Ain Shams University 180
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Not applicableEnded earlyNCT00578292
What this trial is testing

Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO

Who this might be right for
Thalassemia
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Post-approval studies (Phase 4)Study completedNCT00749515
What this trial is testing

Pilot Study for Patients With Poor Response to Deferasirox

Who this might be right for
Transfusion-dependent HemachromatosisThalassemia MajorSickle Cell Disease
Boston Children's Hospital 15
Testing effectiveness (Phase 2)Enrolling By InvitationNCT04432623
What this trial is testing

The BENeFiTS Trial in Beta Thalassemia Intermedia

Who this might be right for
Beta Thalassemia IntermediaSickle Cell Disease
Phoenicia BioScience 36
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableStudy completedNCT02198508
What this trial is testing

Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia Patients

Who this might be right for
Beta-thalassemia Major
China Medical University Hospital 13
Testing effectiveness (Phase 2)Study completedNCT03271541
What this trial is testing

Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-Thalassemia

Who this might be right for
Beta-Thalassemia
Hoffmann-La Roche 12
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Not applicableLooking for participantsNCT07207577
What this trial is testing

Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD

Who this might be right for
Beta Thalassemia Transfusion Dependent
Centre Hospitalier Metropole Savoie 36
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Not applicableActive Not RecruitingNCT03275051
What this trial is testing

Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)

Who this might be right for
Beta Thalassaemia
IRCCS San Raffaele 9
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Testing effectiveness (Phase 2)Study completedNCT07370922
What this trial is testing

Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Ain Shams University 80
Not applicableLooking for participantsNCT06314529
What this trial is testing

Long-term Follow-up Study of BHC001 for TDT

Who this might be right for
Thalassemia, Beta
Bioray Laboratories 6
Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
Large-scale testing (Phase 3)Active Not RecruitingNCT04770779
What this trial is testing

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 258
Post-approval studies (Phase 4)Looking for participantsNCT06606886
What this trial is testing

Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

Who this might be right for
Transfusion Dependent Beta-thalassemia
Bahria University 96
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