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Results for “Transfusion Dependent Iron Overload”

28 trials

Showing 20 of 28 results

Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Testing effectiveness (Phase 2)Study completedNCT00349453
What this trial is testing

Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Who this might be right for
Hemochromatosis
Lipomed 24
Post-approval studies (Phase 4)Ended earlyNCT01818726
What this trial is testing

Safety and Efficacy of Exjade in the Treatment of Transfusion-dependent Iron Overload in Aplastic Anemia Patients

Who this might be right for
Aplastic Anemia
Novartis Pharmaceuticals 15
Not applicableStudy completedNCT01874405
What this trial is testing

Retrospective Evaluation of Adult and Pediatric Transfusion-dependent Patients Treated With Deferasirox Therapy

Who this might be right for
Iron Overload
University of Campania Luigi Vanvitelli 80
Testing effectiveness (Phase 2)Ended earlyNCT03381833
What this trial is testing

A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia

Who this might be right for
Beta-Thalassemia
La Jolla Pharmaceutical Company 84
Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
Testing effectiveness (Phase 2)Study completedNCT02477631
What this trial is testing

Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients

Who this might be right for
Myelodysplastic Syndrome With Low-grade LesionsIron Overload Due to Repeated Red Blood Cell Transfusions
Sheba Medical Center 19
Testing effectiveness (Phase 2)Study completedNCT04614779
What this trial is testing

Long-term Clinical Study of CN128 in Thalassemia Patients

Who this might be right for
ThalassemiaIron Overload
Hangzhou Zede Pharma-Tech Co., Ltd. 18
Testing effectiveness (Phase 2)Ended earlyNCT02943668
What this trial is testing

Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome

Who this might be right for
AnemiaMyelodysplastic Syndrome
Fred Hutchinson Cancer Center 2
Testing effectiveness (Phase 2)WithdrawnNCT03801889
What this trial is testing

SP-420 in Subjects With Transfusion-dependent Beta-Thalassemia or Other Rare Anemias

Who this might be right for
Iron OverloadBeta-Thalassemia
Abfero Pharmaceuticals, Inc
Large-scale testing (Phase 3)Study completedNCT00529152
What this trial is testing

Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients

Who this might be right for
Iron Overload
ApoPharma 100
Post-approval studies (Phase 4)Study completedNCT00481143
What this trial is testing

Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload

Who this might be right for
Myelodysplastic SyndromesTransfusion Dependent Iron Overload
Novartis Pharmaceuticals 63
Testing effectiveness (Phase 2)Study completedNCT05355766
What this trial is testing

Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients

Who this might be right for
ThalassemiaIron Overload
Hangzhou Zede Pharma-Tech Co., Ltd. 16
Testing effectiveness (Phase 2)Looking for participantsNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 95
Not applicableStudy completedNCT00466063
What this trial is testing

ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox

Who this might be right for
Anemia
Novartis Pharmaceuticals 108
Not applicableStudy completedNCT04515680
What this trial is testing

Endocrine Function During Deferasirox Therapy

Who this might be right for
Iron OverloadTransfusion-dependent ThalassemiaEndocrine; Complications
University of Campania Luigi Vanvitelli 426
Testing effectiveness (Phase 2)Study completedNCT01740713
What this trial is testing

Pharmacokinetic Study of Deferiprone in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 23
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Testing effectiveness (Phase 2)Study completedNCT02435212
What this trial is testing

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Who this might be right for
Transfusion-dependent Anemia
Novartis Pharmaceuticals 224
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