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Results for “Transfusion Dependent Iron Overload”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Testing effectiveness (Phase 2)Study completedNCT02435212
What this trial is testing

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Who this might be right for
Transfusion-dependent Anemia
Novartis Pharmaceuticals 224
Testing effectiveness (Phase 2)Study completedNCT02477631
What this trial is testing

Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients

Who this might be right for
Myelodysplastic Syndrome With Low-grade LesionsIron Overload Due to Repeated Red Blood Cell Transfusions
Sheba Medical Center 19
Testing effectiveness (Phase 2)Ended earlyNCT02943668
What this trial is testing

Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome

Who this might be right for
AnemiaMyelodysplastic Syndrome
Fred Hutchinson Cancer Center 2
Post-approval studies (Phase 4)Study completedNCT03591575
What this trial is testing

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children

Who this might be right for
Beta Thalassemia Major AnemiaIron Overload
Chiesi Canada Corp 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT06421636
What this trial is testing

Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Who this might be right for
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Regeneron Pharmaceuticals 19
Testing effectiveness (Phase 2)Study completedNCT00901199
What this trial is testing

Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload

Who this might be right for
ThalassemiaIron Overload
Elliott Vichinsky 22
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Post-approval studies (Phase 4)Study completedNCT00564941
What this trial is testing

Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload

Who this might be right for
Myelodysplastic SyndromesBeta-Thalassemia
Novartis Pharmaceuticals 309
Testing effectiveness (Phase 2)Ended earlyNCT01459718
What this trial is testing

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Who this might be right for
Transfusion-dependent β-thalassemia PatientsCardiac Iron Overload
Novartis Pharmaceuticals 32
Testing effectiveness (Phase 2)Study completedNCT04614779
What this trial is testing

Long-term Clinical Study of CN128 in Thalassemia Patients

Who this might be right for
ThalassemiaIron Overload
Hangzhou Zede Pharma-Tech Co., Ltd. 18
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Large-scale testing (Phase 3)Study completedNCT01033747
What this trial is testing

Safety and Efficacy of Deferasirox in Patients With Transfusion Dependent Iron Overload - a Non-comparative Extension Study

Who this might be right for
Liver Iron Overload
Novartis Pharmaceuticals 70
Testing effectiveness (Phase 2)Ended earlyNCT03381833
What this trial is testing

A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia

Who this might be right for
Beta-Thalassemia
La Jolla Pharmaceutical Company 84
Large-scale testing (Phase 3)Study completedNCT00529152
What this trial is testing

Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients

Who this might be right for
Iron Overload
ApoPharma 100
Not applicableStudy completedNCT00466063
What this trial is testing

ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With Deferasirox

Who this might be right for
Anemia
Novartis Pharmaceuticals 108
Large-scale testing (Phase 3)Study completedNCT00171821
What this trial is testing

A Study Assessing the Efficacy and Safety of Deferasirox in Patients With Transfusion-dependent Iron Overload

Who this might be right for
Transfusion-dependent Iron Overload
Novartis Pharmaceuticals 1,784
Not applicableStudy completedNCT02090699
What this trial is testing

MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias

Who this might be right for
Thalassemia MajorChronic Blood Transfusion Related Iron Overload
University Health Network, Toronto 42
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
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