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Results for “Transfusion Dependent Thalassemia”

131 trials

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Showing 20 of 131 results

Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Testing effectiveness (Phase 2)WithdrawnNCT04938635
What this trial is testing

Efficacy and Safety Study of Multiple Doses of VIT-2763 in Adults With Transfusion-dependent Beta-thalassemia

Who this might be right for
Beta-Thalassemia
Vifor (International) Inc.
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Not applicableLooking for participantsNCT06219239
What this trial is testing

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Post-approval studies (Phase 4)Study completedNCT03591575
What this trial is testing

Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children

Who this might be right for
Beta Thalassemia Major AnemiaIron Overload
Chiesi Canada Corp 64
Testing effectiveness (Phase 2)Study completedNCT07370922
What this trial is testing

Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Ain Shams University 80
Not applicableEnded earlyNCT03329404
What this trial is testing

Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE)

Who this might be right for
Transfusion Dependent Thalassemia
Terumo BCTbio 9
Testing effectiveness (Phase 2)Study completedNCT00390858
What this trial is testing

A 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.

Who this might be right for
Transfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia
Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Looking for participantsNCT06364774
What this trial is testing

ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

Who this might be right for
Beta-Thalassemia
Children's Hospital of Philadelphia 12
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Testing effectiveness (Phase 2)Study completedNCT04614779
What this trial is testing

Long-term Clinical Study of CN128 in Thalassemia Patients

Who this might be right for
ThalassemiaIron Overload
Hangzhou Zede Pharma-Tech Co., Ltd. 18
Not applicableLooking for participantsNCT06314529
What this trial is testing

Long-term Follow-up Study of BHC001 for TDT

Who this might be right for
Thalassemia, Beta
Bioray Laboratories 6
Very early researchNot Yet RecruitingNCT06678165
What this trial is testing

A Pilot Study on the Safety and Efficacy of YOLT-204 for Transfusion-Dependent Beta-Thalassemia

Who this might be right for
Transfusion Dependent Beta Thalassemia
First Affiliated Hospital of Guangxi Medical University 3
Testing effectiveness (Phase 2)Looking for participantsNCT06490627
What this trial is testing

Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia

Who this might be right for
Fetal HemoglobinThalassemia MajorGenetic Disease
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 54
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07721480
What this trial is testing

Gene Therapy for Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
Beta Thalassemia Transfusion Dependent
Prince of Wales Hospital, Shatin, Hong Kong 6
Post-approval studies (Phase 4)Study completedNCT06606886
What this trial is testing

Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

Who this might be right for
Transfusion Dependent Beta-thalassemia
Bahria University 96
Testing effectiveness (Phase 2)Study completedNCT01709032
What this trial is testing

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Who this might be right for
Thalassemia Major With Severe Transfusional Iron Overload
Children's Hospital of Philadelphia 9
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 100
Testing effectiveness (Phase 2)Ended earlyNCT04059406
What this trial is testing

Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)

Who this might be right for
Beta Thalassemia Intermedia
Ionis Pharmaceuticals, Inc. 29
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