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Results for “Transfusion Dependent Thalassemia”

122 trials

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Showing 20 of 122 results

Post-approval studies (Phase 4)Study completedNCT03992001
What this trial is testing

Impact of the Preparation Method of Red Cell Concentrates on Transfusion Indices in Thalassemic Patients

Who this might be right for
Thalassemia Major
Università degli Studi di Ferrara 55
Testing effectiveness (Phase 2)Study completedNCT03802201
What this trial is testing

Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia

Who this might be right for
β-thalassemiaIneffective ErythropoiesisChronic Anemia
Protagonist Therapeutics, Inc. 63
Large-scale testing (Phase 3)Study completedNCT01825512
What this trial is testing

Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients

Who this might be right for
Chronic Iron Overload
Consorzio per Valutazioni Biologiche e Farmacologiche 435
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
Testing effectiveness (Phase 2)Study completedNCT00349453
What this trial is testing

Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Who this might be right for
Hemochromatosis
Lipomed 24
Testing effectiveness (Phase 2)Looking for participantsNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 150
Very early researchLooking for participantsNCT05864170
What this trial is testing

The Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
β-thalassemia
Shenzhen Hemogen 3
Post-approval studies (Phase 4)UnknownNCT05462548
What this trial is testing

The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world Study

Who this might be right for
Thalassemia MajorTransfusion-dependent Anemia
Sun Yat-sen University 20
Not applicableActive Not RecruitingNCT03275051
What this trial is testing

Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)

Who this might be right for
Beta Thalassaemia
IRCCS San Raffaele 9
Early research (Phase 1)Looking for participantsNCT05757245
What this trial is testing

A Study Evaluating the Safety and Efficacy of the GMCN-508A Drug Product in Transfusion-dependent α-Thalassemia Participants

Who this might be right for
Transfusion-dependent α-Thalassemia
First Affiliated Hospital of Guangxi Medical University 5
Early research (Phase 1)Study completedNCT02950857
What this trial is testing

EPEG in Beta Thalassemia Patients

Who this might be right for
Beta-Thalassemia
Prolong Pharmaceuticals 6
Testing effectiveness (Phase 2)Looking for participantsNCT03653338
What this trial is testing

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Who this might be right for
Sickle Cell AnemiaBeta-thalassemia MajorDiamond-blackfan Anemia
Paul Szabolcs 5
Testing effectiveness (Phase 2)Enrolling By InvitationNCT05577312
What this trial is testing

Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Who this might be right for
Beta-Thalassemia
Bioray Laboratories 39
Testing effectiveness (Phase 2)Looking for participantsNCT06308159
What this trial is testing

An Open-label Study of a Gene Therapy Product (Vebeglogene Autotemcel) in Transfusion Dependent Beta-Thalassemia

Who this might be right for
Beta-Thalassemia
Lantu Biopharma 6
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Not applicableStudy completedNCT04515680
What this trial is testing

Endocrine Function During Deferasirox Therapy

Who this might be right for
Iron OverloadTransfusion-dependent ThalassemiaEndocrine; Complications
University of Campania Luigi Vanvitelli 426
Testing effectiveness (Phase 2)Looking for participantsNCT06657391
What this trial is testing

Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent Thalassemia

Who this might be right for
Transfusion Dependent Thalassemia
Rongrong Liu 396
Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Post-approval studies (Phase 4)Looking for participantsNCT06299670
What this trial is testing

Efficacy of Combination of Hdroxyurea and Thalidomide Over Either Hydroxyurea or Thalidomide Alone in the Treatment of Transfusion Dependent Thalassemia in Children: A Quasi-Randomised Clinical Trial

Who this might be right for
Transfusion-dependent Thalassemia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 90
Very early researchLooking for participantsNCT05762510
What this trial is testing

A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TDT]

Who this might be right for
Transfusion Dependent Beta-Thalassemia
First Affiliated Hospital of Guangxi Medical University 5
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